Patella tissue engineering scaffold, and manufacturing material and preparation method thereof

Abstract

The invention provides a patella tissue engineering scaffold. The patella tissue engineering scaffold is formed by magnesium, aluminum, zinc and zirconium in a mass ratio of 85-95: 0-6: 0-4: 0-4. The scaffold has a shape consistent with the patella of a human body and is formed by arrangement of interlacing trabeculae, a plurality of mutually communicating holes are formed among trabeculae, the diameter of each hole is in a range of 0.1 to 0.8 mm, and porosity of the holes is 30 to 80%. The scaffold has the shape consistent with the human patella, can well match with the articular surface of the human patella or the articular surface of the patella of an artificial knee joint and reduces wearing of the patella tissue engineering scaffold, thereby reducing generation of abrasive dust; since the scaffold is prepared from the above-mentioned components, the scaffold is degradable in a human body, metal ions of magnesium ions and the like beneficial to the human body are produced after degradation, so the scaffold does not produce abrasive dust causing harm to the human body. Moreover, the invention further provides a material used for manufacturing the scaffold and a preparation method for the scaffold.

Description

【Technical field】 [0001] The invention relates to the technical field of biomedical tissue engineering, in particular to a material for manufacturing a patella tissue engineering support, a patella tissue engineering support and a preparation method thereof. 【Background technique】 [0002] Patella softening is the degenerative change of the articular cartilage of the patella due to damage, including swelling, fragmentation, detachment and corrosion of the cartilage surface of the patella. An effective treatment for patella softening is patellar replacement surgery. In the existing patella conversion surgery, the patella shell prosthesis is generally used for patella surface replacement. [0003] The material of the patella shell prosthesis is generally non-degradable materials such as polyethylene, and the common patella shell prosthesis includes anatomical type and dome cap type. The contact stress between the anatomical patellar shell prosthesis and the femoral component...

AI Technical Summary

Problems solved by technology

[0004] Due to the low contact stress between the anatomical patella shell prosthesis and the femoral prosthesis, and the high shear stress with the patella, while the dome-shaped patella shell prosthesis is not consistent with the shape of the normal patella, the patellar shell installed in the human body Prosthetics are prone to wear and tear

The patella shell prosthesis is made of non-degradable materials such as polyethylene, and the wear debris formed during the wear process may cause synovitis and metallization, which is harmful to the human body

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