Silver thiosulfate complex or silver-ammonia complex-containing hygroscopic silver-containing product and preparation method thereof

Abstract

The invention relates to a silver thiosulfate complex or silver-ammonia complex-containing hygroscopic silver-containing product and a preparation method thereof. The invention discloses a hygroscopic silver-containing antibacterial product which comprises a silver thiosulfate complex or a silver-ammonia complex as an antibacterial ingredient, the silver thiosulfate complex or the silver-ammonia complex is evenly distributed and combined on the inner side and / or surface, the hygroscopic silver-containing antibacterial product comprises 0.01-10 wt% of silver, and the moisture absorption ability of the hygroscopic silver-containing antibacterial product is 6g / g and above. The invention also provides a preparation method of the hygroscopic silver-containing antibacterial product as well as a silver-containing antibacterial product dressing prepared from the hygroscopic silver-containing antibacterial product. The hygroscopic silver-containing antibacterial product has a very wide antibacterial spectrum, shows strong antibacterial activity to gram-negative bacteria and gram-positive bacteria, is rapid in effect, has light stability, and can be widely applied to chronic infections exudative wounds.

Description

technical field [0001] The invention relates to a hygroscopic silver-containing product, especially a silver-containing product containing silver thiosulfate complex or silver ammonium complex. The article can be used in medical dressings and other antimicrobial fields. Background technique [0002] With the improvement of people's living standards and changes in eating habits, the human disease spectrum presents some new features. Chronic exudative wounds such as venous ulcers, arterial ulcers, diabetic ulcers, traumatic ulcers, and pressure ulcers caused by diabetes, pressure sores, decubitus ulcers, and hypertension have seriously affected people's health. Exudative wounds, as the name suggests, are a type of chronic wounds that secrete a large amount of exudate, and the main components of the exudate are some pus, tissue fluid, and some necrotic tissues and cells. Therefore, in the care of chronic exudative wounds, in addition to fully absorbing wound exudate and provi...

AI Technical Summary

Problems solved by technology

However, most of the silver compounds used in ionic silver-containing dressings are very low in water solubility, such as silver chloride and silver carbonate. , when these small amounts of silver ions are consumed, the insoluble silver compound re-ionizes a small amount of silver ions, and the effect of continuous release of silver ions is achieved through such a dissolution balance

Although the use of ionic silver-containing dressings with low water solubility can continuously release silver ions, the amount of silver ions released after contact with water is relatively small, so a relatively large amount of silver compounds is still required to achieve the desired antibacterial effect

In addition, the silver release performance of this type of wound dressing is average. Based on the calculation of 1% silver content, the 24-hour silver release in 10ml wound simulation fluid is only about 20ppm, which affects its antibacterial effect and function to a certain extent. Time, in addition, most ionic silver-containing dressings are not stable, and the silver-containing dressings will change color after a period of time, which affects their acceptability as a commodity

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