The invention discloses durable highway guardrail paint. The durable highway guardrail paint is prepared from the following raw materials in parts by weight: 6-11 parts of a thickening agent, 3-6 parts of a light stabilizer, 4-8 parts of a dispersing agent, 5-7 parts of a mildew-proof anti-algae agent, 6-11 parts of dipropylene glycol, 3-8 parts of phthalic anhydride, 6-14 parts of organosilicone acrylate, 4-8 parts of hydrogenated castor oil, 6-10 parts of di-tert-butyl peroxy-phthalate, 1-3 parts of a defoaming agent, 4-9 parts of polyvinyl alcohol methyl ester, 5-7 parts of 2-chloroethanesulfonic acid, 1-5 parts of methyl alcohol, 2-6 parts of purified bentonite and 5-10 parts of hydrated alumina. The durable highway guardrail paint has the beneficial effects of high acid and alkali resistance, high corrosion resistance, light stability and small possibility of light deterioration.