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Traditional Chinese medicinal preparation for treating wind phlegm blood stasis in collaterals type brain infarction and preparation method thereof

A technology of traditional Chinese medicine preparations and cerebral infarction, which is applied in the field of traditional Chinese medicine preparations, can solve the problems of easy tolerability, many adverse reactions, and multiple side effects, etc., and achieve the effect of quick onset, short course of treatment, and definite curative effect

Inactive Publication Date: 2014-11-19
HANGZHOU JINPEI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Western medicine treatment of cerebral infarction has a wide range of drugs to choose from, and different diagnosis and treatment plans can be formulated according to the condition. Synthetic drugs are prone to drug resistance and have many side effects. For example, vasodilator drugs can sometimes aggravate severe patients with increased intracranial pressure, have many adverse reactions, and easily lead to tolerance

Method used

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0069] Wherein, when the dosage form of described Chinese medicine is tablet, its preparation method comprises the following steps:

[0070] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, heat and reflux for 4 to 6 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol with an alcohol concentration of 90% to 95% relative to the quality of the medicinal dregs 2 to 4 times, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0071] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 3 hours, pulverized, and s...

Embodiment 1

[0084] Example 1 tablet

[0085] The preparation process of the oral tablet of the present invention is: get Epimedium 220g, Curcuma 180g, Xia Tianwu 260g, Caulis Spatholobus 170g, Vaccaria 210g, Sappan 260g, Liu Jinu 280g, Lingxiaohua 320g, Rose 330g , Passepartout 340g, Citrus aurantium 250g, Trichosanthes peel 220g, Albizia juniper peel 320g, Amber 240g, Morinda officinalis 300g, Chuanxiong 210g, Salvia miltiorrhiza 260g, Ruliancao 240g, Safflower 180g, Kidney fern 260g, Peach kernel 160g, Horsewhip 120g grass, 170g wulingzhi, 220g southern alfalfa, 190g rose, 240g saponins, 220g white mustard and 270g geranium;

[0086] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is 5 times the mass of the mixture, heat and reflux for 5 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the ...

Embodiment 2

[0090] Example 2 Capsules

[0091] The manufacture process of the capsule of the present invention is: get Epimedium 160g, Curcuma 230g, Xia Tian Wu 250g, Caulis Spatholobus 140g, Wangbuliuxing 210g, Sappan 270g, Liu Jinu 220g, Lingxiaohua 250g, Rose 210g, Passepartout 320g, Citrus aurantium 200g, Trichosanthes peel 170g, Albizia juniper 180g, Amber 260g, Morinda officinalis 310g, Chuanxiong 150g, Salvia miltiorrhiza 180g, Ruliancao 190g, Safflower 220g, Kidney fern 260g, Peach kernel 180g, Verbena 200g, 120g wulingzhi, 160g southern alfalfa, 220g Chinese rose, 240g saponins, 180g white mustard and 240g geranium;

[0092] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the qu...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating wind phlegm blood stasis in collaterals type brain infarction and a preparation method thereof. The traditional Chinese medicinal preparation is prepared from the following raw medicinal materials: epimedium, radix curcumae, corydalis decumben, caulis spatholobi, cowherb seed, hematoxylon, artemisia anomala, trumpet creeper, rose, liquidambar formosana hance, immature bitter orange, snakegourd fruit peel, cortex albiziae, amber, medicinal indianmulberry root, rhizoma ligustici wallichii, salvia miltiorrhiza, aster subulatus, safflower carthamus, tuber fern, peach kernel, verbena, trogopterus dung, toothed burclover, Chinese rose, honeylocust, sinapsis alba and tabasheer. The traditional Chinese medicinal preparation disclosed by the invention has the beneficial effects that the preparation can achieve the effects of promoting blood circulation to remove blood stasis, eliminating phlegm and freeing channels, can be used for treating the wind phlegm blood stasis in collaterals type brain infarction, adopts the traditional Chinese medicinal theories as guidance, conducts syndrome differentiation and treatment based on the holistic view, is free of toxic and side effect, can dilate blood vessels, carry out thrombolysis, anticoagulation and dilution to the blood, and improve the microcirculation, and has the advantages of fast effectiveness, high efficiency, definite curative effect, short treatment course, non-toxic non-side effects, low price and the like.

Description

[0001] Technical field [0002] The present invention involves the technology field of traditional Chinese medicine preparations, and specially involves a traditional Chinese medicine preparation and preparation method for treating wind and sputum blood stasis and blood stasis, and the preparation of the vein collateral cerebral infarction. [0003] Background technique [0004] Cerebral infarction (cerebral infarction, ischemia stroke) refers to the limited necrotic necrosis or brain softening caused by blood supply disorders, ischemia, and hypoxia caused by brain blood supply, and the clinical types of cerebral infarction are cerebral thrombosisFormed, cavity infarction and cerebral embolism, cerebral infarction accounts for 80%of all strokes. [0005] The cause of cerebral infarction is mainly in the following aspects: 1. Heartogenicity: 60-75%, common diseases due to chronic atrial fibrillation, the main source of embolism is rheumatoid heart valve disease, endometritis remov...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10A61K35/10
Inventor 苏琳
Owner HANGZHOU JINPEI TECH