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Pharmaceutical preparation for treating cerebral thrombosis

A technology of pharmaceutical preparations and raw materials, which is applied in the field of traditional Chinese medicine, can solve the problem of no therapeutic drugs for cerebral thrombosis, and achieve the effects of no toxic side effects, high therapeutic effect, and safe medication

Inactive Publication Date: 2014-12-24
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine has no effective therapeutic drugs in the treatment of cerebral thrombosis. In the treatment of cerebral thrombosis, Western medicine focuses on the application of anticoagulant drugs, trophic nerve cells and other drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0055] The present invention also provides the preparation method of above-mentioned pharmaceutical preparation, specifically:

[0056] The first step is to combine Puhuang, peach kernel, Chuanxiong, leech, Tianzhuhuang, Acanthopanax, Astragalus, Millae, Sappan, Salvia, Gorgon, Huajuhong, Eucommia, nutmeg, rhubarb, blue cloth and heterophylla Pulverize respectively, cross 20 mesh sieves, put into a blender and stir, mix, dissolve the mixed mixture in ethanol with an alcohol concentration of 80% to 90%, the amount of added ethanol is 2% of the quality of the mixture obtained in this step ~4 times, reflux extraction 2~4 times, filter, combine the filtrates, concentrate under reduced pressure to remove ethanol, obtain a dry paste, then dry, pulverize, add 3~5 times the amount of powder relative to its mass Dissolve in water, filter, add 10% hydrochloric acid to adjust the pH to 3-4, stand still for 2-4 hours, filter, extract the filtrate with ethanol, concentrate the extract unde...

Embodiment 1

[0060] The preparation of embodiment 1 injection 1

[0061]Puhuang 25g, peach kernel 35g, Chuanxiong 40g, leech 20g, Tianzhuhuang 40g, Acanthopanax 55g, Astragalus 50g, Milletus 35g, Sappan 35g, Salvia 30g, Gorgon 30g, Huajuhong 25g, Eucommia 35g, nutmeg 30g, 25g of rhubarb, 35g of blue cloth and 40g of Radix Pseudostellariae were crushed separately, passed through a 20-mesh sieve, put into a blender and stirred, mixed, and the mixed mixture was dissolved in 1.8kg of ethanol with an alcohol concentration of 90%, and extracted by reflux 3 times, filter, combine the filtrates, concentrate under reduced pressure to remove ethanol, obtain a dry paste, then dry, pulverize, dissolve the pulverized powder in water relative to 2.3kg, filter, and add 10% hydrochloric acid to adjust the pH The value is 4, stand still for 4 hours, filter, the filtrate is extracted with ethanol, the extract is concentrated under reduced pressure into a dry paste, then dried, and crushed into a fine powder...

Embodiment 2

[0062] Example 2 Preparation of Injection 2

[0063] Puhuang 23g, peach kernel 33g, Chuanxiong 38g, leech 18g, Tianzhu Huang 38g, Acanthopanax 53g, Astragalus 48g, Milletus 33g, Sappan 33g, Salvia 28g, Gorgon 28g, Huajuhong 23g, Eucommia 33g, nutmeg 28g, 23g of rhubarb, 33g of blue cloth and 38g of Radix Pseudostellariae were crushed separately, passed through a 20-mesh sieve, put into a blender and stirred, mixed, and the mixed mixture was dissolved in 1.5kg of ethanol with an alcohol concentration of 90%, and extracted by reflux 3 times, filter, combine the filtrates, concentrate under reduced pressure to remove ethanol, obtain a dry paste, then dry, pulverize, dissolve the pulverized powder in 2 kg of water, filter, add 10% hydrochloric acid to adjust the pH value 4, stand still for 4 hours, filter, the filtrate is extracted with ethanol, the extract is concentrated under reduced pressure into a dry paste, then dried, and crushed into a fine powder of 100 meshes, 48g of Des...

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PUM

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Abstract

The invention provides a pharmaceutical preparation for treating the cerebral thrombosis. The pharmaceutical preparation comprises bulk drugs such as christina loosestrife, pollen typhae, rhizoma alismatis, peach kernels, ligusticum wallichii, siegesbeckiae Herba, haws, hirudo, xanthii fructus, tabasheer, coicis semen, acanthopanacis senticosi radix et rhizoma seu caulis, astragali radix, spatholobi caulis, sappanlignum, salvia miltiorrhiza, acori calami rhizoma, gordon euryale, cochinchinese asparagus roots, mongolian snakegourd, angelica roots, pummelo peels, encomia bark, myristicae semen, conyza japonica, salvia, Chinese taxillus herb, radix et rhizome rhei franzenbachii, herba gei and heterophylly falsestarwort roots. The pharmaceutical preparation is superior to the western medicine in treatment effect and is convenient and safe to take, free of toxic and side effects, cheap and worthy of popularization and application.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical preparation for treating cerebral thrombosis. Background technique [0002] Cerebral thrombosis belongs to the type of ischemia in cerebrovascular diseases. After the internal cerebral artery wall is damaged, the blood viscosity of the body increases and the flow velocity slows down, which leads to thrombosis, which leads to the occurrence of brain tissue in the blood supply area of ​​the diseased blood vessel. Degeneration and necrosis after ischemia and hypoxia, and clinical symptoms such as hemisensory disturbance, hemiplegia, and slurred speech. Cerebral thrombosis is a common cerebrovascular disease, which occurs frequently in middle-aged and elderly people, with high mortality and disability rates and poor prognosis. Cerebral thrombosis is more common in elderly people with arteriosclerosis between 50 and 70 years old. Men outnumber wo...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P7/02A61P9/10
Inventor 不公告发明人
Owner QINGDAO HUAREN TECH INCUBATOR
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