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Lecithin-containing aqueous emulsifying agent as well as preparation method and application thereof

A technology of lecithin and emulsification tank, which is applied in the field of water-based oil-water emulsion, and can solve the problems of affecting the digestion and absorption of the composition and different bioavailability

Inactive Publication Date: 2015-03-11
FUZHOU QIANZHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The unfavorable effect is that lecithin and the composition with synergistic pharmacological effects with lecithin, its existing state greatly affects the digestion and absorption of the composition in the human body, and is absorbed in the form of passive diffusion in the body; in addition, The bioavailability of different formulation combinations, dosage forms, preparation methods or ways of existence is also significantly different

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0107] Embodiment 1, compound lecithin emulsion and preparation method thereof

[0108] The prescription quantity is calculated by weight percentage and contains:

[0109] Lecithin 0.5%~5.5%, preferably 2.5%,

[0110] Arachidonic acid 0.03%~3%, preferably 1.5%,

[0111] Sucralose 0~0.05%, preferably 0.01%,

[0112] Add purified water to 100%;

[0113] Preparation: (1) Ingredients: Weigh sucralose according to the formula and add it into purified water to make it completely dissolved. Separately weigh lecithin and arachidonic acid, add them into purified water in turn, set the volume to the required production volume, stir, mix and disperse evenly ;

[0114] (2) Emulsification: Put the liquid prepared in (1) in the emulsification tank, and continuously feed 20-30L / min nitrogen or carbon dioxide from the bottom of the emulsification tank, when the liquid temperature is 45-65°C and the stirring speed is greater than 2500r Under the condition of 1 / min, carry out the emulsific...

Embodiment 2

[0119] Embodiment 2, compound phospholipid emulsion preparation and preparation method thereof

[0120] The prescription quantity is calculated by weight percentage and contains:

[0121] Lecithin 0.5%~5%, preferably 4.0%,

[0122] Phosphatidylserine 0.05% to 3%, preferably 0.3%,

[0123] Add purified water to 100%;

[0124] Preparation: (1) Ingredients: Weigh lecithin and phosphatidylserine according to the formula, add them into purified water in turn, set the volume to the required production volume, stir, mix and disperse evenly;

[0125] (2) Emulsification: Put the liquid prepared in (1) in the emulsification tank, and continuously feed 20-30L / min nitrogen or carbon dioxide from the bottom of the emulsification tank, when the liquid temperature is 45-65°C and the stirring speed is greater than 2800r Under the condition of 1 / min, carry out the emulsification operation for 15-30 minutes, and then pass through the interlayer cooling water to cool the emulsion to 25°C with...

Embodiment 3

[0130] Embodiment 3, composite phospholipid emulsion and preparation method thereof

[0131] The prescription quantity is calculated by weight percentage and contains:

[0132] Lecithin 0.5% to 8%, preferably 5.5%,

[0133] Linolenic acid in peony seed oil (linolenic acid content ≥ 38%) 0.5% to 10%, preferably 1.5% (based on linolenic acid content),

[0134] Add purified water to 100%;

[0135] Preparation: (1) Ingredients: Weigh lecithin and peony seed oil linolenic acid according to the formula, add them into purified water in turn, set the volume to the required production volume, stir, mix and disperse evenly;

[0136] (2) Emulsification: Put the liquid prepared in (1) in the emulsification tank, and continuously feed 20-30L / min nitrogen or carbon dioxide from the bottom of the emulsification tank, when the liquid temperature is 45-65°C and the stirring speed is greater than 2800r Under the condition of 1 / min, carry out the emulsification operation for 15-30 minutes, an...

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Abstract

The invention provides an emulsion composition containing lecithin, other liposoluble substances and water. The water content of the emulsion composition in percent by weight is larger than 70%; the other liposoluble substances comprise one or more of arachidonic acid, linolenic acid, linoleic acid, conjugated linoleic acid, conjugated linoleic acid glyceride, phosphatidylserine, polyene phosphatidyl choline, phosphatidyl ethanolamine, phosphatidylinositol, phosphatidyl glycerol, phytosterol, phytosterol ester, plant stanol ester and medium-long-chain fatty acid. The preparation method of the emulsion composition comprises the steps of mixing and emulsifying the lecithin and the other liposoluble substances with the water to obtain the emulsion composition, wherein the water content of the emulsion composition in percent by weight is larger than 70%, and the particle sizes of fat globules in the emulsion are smaller than 5 micrometers. Furthermore, the invention provides a preparation method of the emulsion composition and the application of the emulsion composition in oral phosphatide and unsaturated fatty acid replenishers and protection of heart and cerebral vessels.

Description

technical field [0001] The invention relates to a health food composition, in particular to a water-based oil-water emulsion containing lecithin, a preparation method and application thereof. [0002] The health product composition of the present invention refers to medicine, medical food, health food, nutritional food or cosmetics. Background technique [0003] The general name of lecithin, phosphatidylcholine, is known as the "third nutrient" alongside protein and vitamins. Since the 1990s, phospholipid research has achieved remarkable results in the fields of life science and brain science. Lecithin It has good effects on the nutrition and health of the human body, as shown in: 1. Human nutritional needs: 90% of the exogenous choline required by the human body is provided by lecithin, and lecithin provides choline with two major benefits: first, Unlike free choline, which can be degraded into methylamine due to the action of microorganisms in the intestinal tract; secon...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K9/107A61K31/685A61K45/06A61P3/02A61P9/00A61P1/16A61P9/12A61K8/55A61Q19/00A23L33/00
CPCA23L33/10A23J7/00A23L33/00A23L33/11A23L33/12A23V2002/00A23V2200/30A23V2200/318A23V2200/32A23V2200/326A23V2250/1842A23V2250/1848A23V2250/185A23V2250/1852A23V2250/1862A23V2250/1866A23V2250/1872A23V2250/1874A23V2250/1876A23V2250/1878
Inventor 张耿元王保红白东跃唐湘成俞世宏
Owner FUZHOU QIANZHENG PHARMA
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