Selenous acidized beta-lactoglobulin, preparation method and application

A technology of lactoglobulin and selenium acidification, which is applied in the preparation method of peptides, plasma globulin/lactoglobulin, mammalian protein, etc., can solve the problem of dose dependence of antioxidant effect, narrow range of therapeutic dose and toxic dose of inorganic selenium, etc. problem, to achieve the effect of stable product properties, easy storage, and simple preparation process
CN104479003AInactive Publication Date: 2015-04-01TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
Publication Date
2015-04-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a synthesis and preparation method and an application of selenous acidized beta-lactoglobulin. Beta-lactoglobulin and SeO2 are taken as raw materials, selenous acid groups are introduced into beta-lactoglobulin with an oxidation-reduction method, and a novel organic selenium source is prepared. The preparationmethodcomprises the following steps: preparation of selenous acid; preparation ofa beta-lactoglobulinliquid containing selenous acid; introduction of selenous acid radical; filterationand centrifugation; freeze drying; and obtaining of a pure product selenous acidized beta-lactoglobulin. The obtained selenous acidized beta-lactoglobulin has high nutritive value, stable properties, and anticancer and anti-aging effects, and is an excellent organic selenium source. The method not only has greattheoretical significance on development of organic selenized protein, but also has great social practical significance on healthy aging.
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Description

technical field

[0001] The invention belongs to the interdisciplinary field of food science and technology, organic chemistry, and biopharmaceutical fields, and provides a selenized β-lactoglobulin, a synthesis preparation method and an application. Background technique

[0002] Selenium is an essential trace element for living organisms and an important antioxidant in the body. Selenium affects free radical metabolism, antioxidant function, immune function, reproductive function and cell apoptosis by regulating selenoprotein or selenium enzyme (glutathione peroxidase and phospholipid hydrogen glutathione peroxidase) Wait. A large number of studies at home and abroad have shown that selenium is closely related to the aging of the body. Selenium, as a regulator of brain function, is involved in various neurodegenerations that accompany aging.

[0003] Soil selenium is the main selenium source required by organisms. However, the abundance of selenium in the earth's crust is...

Claims

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