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Jiawei Yupingfeng gel, preparation method and purpose thereof

A screen gel and gel technology, applied in the field of flavored jade screen gel and its preparation, can solve chronic UV damage and other problems, achieve reduction of damage, obvious photoaging skin lesions, and improvement of photoaging skin lesions Effect

Active Publication Date: 2015-04-08
TIANJIN NANKAI HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] The present invention explains that in order to solve the problem of chronic UV damage after ultraviolet radiation, it provides a traditional Chinese medicine flavored jade screen gel and its preparation method and use

Method used

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  • Jiawei Yupingfeng gel, preparation method and purpose thereof
  • Jiawei Yupingfeng gel, preparation method and purpose thereof
  • Jiawei Yupingfeng gel, preparation method and purpose thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] A flavored Yupingfeng gel, weigh 60g of Astragalus membranaceus, 20g of Scutellaria baicalensis, 30g of Atractylodes macrocephala and 30g of Fangfeng, mix them, add 80% ethanol to extract twice, and the amount of alcohol added is 10 times the amount of medicinal materials (W / V), 1400mL , were extracted for 2 hours, filtered, the filtrates were combined, and the recovered ethanol was concentrated to extract 68g.

[0057] Add 4.25g of glycerin, 4.25g of propylene glycol, and 0.85g of azone to the above extract, stir, add 0.85g of Carbomer-980, 1mL of ethanol solution containing 0.05g of ethylparaben, stir, and let it stand for more than 24 hours. Add 0.85g of triethanolamine, add purified water to make up to 85g, and stir well and evenly.

Embodiment 2

[0059] A flavored Yupingfeng gel, first weigh 60g of Astragalus membranaceus and 15g of Scutellaria baicalensis, mix them, add 70% ethanol to extract twice, the amount of alcohol added is 8 times the amount of medicinal materials (W / V) 600mL, and extract for 1.5 hours respectively , filtered, the filtrates were combined, and the recovered ethanol was concentrated to extract 38g.

[0060] Another 20g each of Atractylodes macrocephala and Fangfeng, mixed and crushed through No. 1 Pharmacopoeia sieve, added 8 times of water to measure 320mL, extracted volatile oil with volatile oil extractor for 8 hours, collected 0.15mL of volatile oil, diluted to 0.65mL with Tween-80, added to the above in the extract.

[0061] Finally, add 2g of glycerin, 2g of propylene glycol, 0.65g of azone, 0.4mL of ethanol solution containing 0.02g of ethylparaben to the above extract, stir, add 0.7g of Carbomer-980, stir, and let it stand for more than 24 hours , add 0.7g of triethanolamine, add purifie...

Embodiment 3

[0063] A flavored Yupingfeng gel. Weigh 60g of Radix Astragali, 20g of Atractylodes Rhizoma Atractylodes Rhizome, 20g of Fangfeng, and 10g of Scutellaria baicalensis, add water and extract 3 times. Filtrate, combine the filtrates, concentrate to an extract with a specific gravity of 1.25, add 95% ethanol to make the alcohol content reach 70%, make it precipitate, centrifuge or filter, recover ethanol from the supernatant or filtrate, and continue to concentrate to 95g of extract.

[0064] To the above extract, add 3.3g of glycerin, 3.3g of propylene glycol, 1g of azone, 2mL of ethanol solution containing 0.1g of ethylparaben, stir, add 0.66g of Carbomer-980 and stir, let stand for more than 24 hours, add Triethanolamine 1.1g, add purified water to make up to 110g, fully stir evenly.

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Abstract

The invention discloses Jiawei Yupingfeng gel, a preparation method and a purpose thereof and belongs to pharmaceutical products with traditional Chinese herbal medicine. The Jiawei Yupingfeng gel is prepared through weighing milkvetch root, bighead atractylodes rhizome, Chinese parsnip root and baical skullcap root according to weight parts, and extracting and condensing to obtain extract through ethanol; adding pharmaceutic accessories (water-soluble polymer matrix-Carbopol, wetting agent-glycerol, propylene glycol, penetration enhancer-azone, pH regulating agent-triethanolamine, preservative-ethylparaben and pure water) to the extract according to the weight-to-volume ratio, and stirring uniformly. The Jiawei Yupingfeng gel is based on treating an internal illness by external treatment, and effective parts or effective ingredients in the traditional Chinese medicine raw materials are extracted to prepare into the gel according to the external transdermal absorption feature; the gel is directly used for the skin damaged by ultraviolet, and the gel does not need the first pass effect of the liver and reduces the damage of gastrointestinal tract enzyme to the gel; the gel can obviously improve the light aging skin damage; the gel has outstanding curative effect in the light aging treatment aspect.

Description

technical field [0001] The invention relates to a medicine preparation containing traditional Chinese herbal medicine, in particular to a flavored jade screen gel and its preparation method and application. Background technique [0002] The skin, like any other organ, undergoes aging, which intensifies with age. In addition to endogenous factors in skin aging, the influence of exogenous factors on the skin cannot be ignored. With the progress of human society and the rapid development of industry, the destruction of the ozone layer has caused human beings to suffer from excessive ultraviolet radiation, which has become one of the important exogenous factors of aging. People define the changes of skin tissue, physiology and morphology as photoaging after long-term exposure to ultraviolet rays, that is, chronic UV damage. [0003] Clinically, it can be manifested as loose skin at the exposed area, thick and deep wrinkles, nodules, leather-like appearance, increased pigment s...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/06A61K9/70A61P17/18
CPCA61K9/06A61K36/238A61K36/284A61K36/481A61K36/539A61K47/22A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 蒋靖刘俊红夏立君韩旭李定超
Owner TIANJIN NANKAI HOSPITAL
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