A kind of preparation method of absorbable suture
A suture and casing technology, applied in the field of suture, can solve the problems of suture quality influence, mechanical strength decline, material hydrolysis deterioration, etc., to achieve the effect of accelerating wound healing, stabilizing absorption period and avoiding infection
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Embodiment 1
[0021] The present invention is used to prepare a kind of absorbable suture, and its preparation method comprises the following steps:
[0022] (1) Isolate protein chorion: select fresh goat casing, wash the inner wall of the casing, and scrape the intestinal chorion, mucous membrane, serosa, etc. in the casing to make it fall off;
[0023] (2) Purification of collagen fibers: After cleaning the above-mentioned sheep casings, put them in 0.9% sodium chloride solution and soak for 30 minutes. After taking them out, put them directly in 30% sodium chloride solution and soak them for 10 minutes, and then separate and remove them. The fat in the collagen fibers, resulting in relatively pure collagen fibers;
[0024] (3) Degreasing and degreasing: the above-mentioned purified collagen fibers are added to a 0.5% sodium hydroxide solution at a temperature of 40 degrees Celsius and soaked for 15 minutes. The solution is also added with 1% by weight of dodecyl sulfate. Sodium, so that...
Embodiment 2
[0032] The present invention is used to prepare a kind of absorbable suture, and its preparation method comprises the following steps:
[0033] (1) Isolate protein chorion: select fresh goat casing, wash the inner wall of the casing, and scrape the intestinal chorion, mucous membrane, serosa, etc. in the casing to make it fall off;
[0034] (2) Purification of collagen fibers: After cleaning the above-mentioned sheep casings, put them in 0.9% sodium chloride solution and soak for 30 minutes. After taking them out, put them directly in 30% sodium chloride solution and soak them for 10 minutes, and then separate and remove them. The fat in the collagen fibers, resulting in relatively pure collagen fibers;
[0035] (3) Degreasing and degreasing: The above-mentioned purified collagen fibers are added to a 2% sodium hydroxide solution at a temperature of 60 degrees Celsius and soaked for 10 minutes. The solution is also added with 0.5% by weight of dodecylbenzene. Sodium sulfonate...
Embodiment 3
[0043] The present invention is used to prepare a kind of absorbable suture, and its preparation method comprises the following steps:
[0044] (1) Isolate protein chorion: select fresh goat casing, wash the inner wall of the casing, and scrape the intestinal chorion, mucous membrane, serosa, etc. in the casing to make it fall off;
[0045] (2) Purification of collagen fibers: After cleaning the above-mentioned sheep casings, put them in 0.9% sodium chloride solution and soak for 30 minutes. After taking them out, put them directly in 30% sodium chloride solution and soak them for 10 minutes, and then separate and remove them. The fat in the collagen fibers, resulting in relatively pure collagen fibers;
[0046] (3) Degreasing and degreasing: the above-mentioned purified collagen fibers are added to a 1.5% sodium hydroxide solution with a temperature of 55 degrees Celsius and soaked for 12 minutes. The solution is also added with 0.8% sodium stearate by weight. So that the oi...
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