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Pharmaceutical composition for treating wound infection after pediatric fracture

A composition and medicine technology, applied in the field of medicine, can solve the problems that antibiotics are easy to produce drug resistance, high cost, great pain for patients, etc., and achieve the effects of promoting wound healing, safe and reliable effect, and infection control.

Active Publication Date: 2015-04-22
邳州市润宏实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, debridement surgery and dressing replacement are often used, which causes great pain for patients, long hospital stay, high cost, and long-term use of antibiotics is easy to produce drug resistance, and the curative effect is slow.

Method used

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  • Pharmaceutical composition for treating wound infection after pediatric fracture

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1 Preparation of the pharmaceutical composition of the present invention

[0015] Taking ointment as an example, the preparation process steps of the pharmaceutical composition of the present invention are as follows:

[0016] (1) Weigh 80 grams of frankincense, 50 grams of centella asiatica, 150 grams of calabash vine, 120 grams of Eucommia ulmoides, 80 grams of licorice, 50 grams of argyi, 100 grams of sardine grass, 120 grams of burnet, and 80 grams of rose leaves , 150 grams of honeysuckle, 50 grams of quince, 100 grams of Panax notoginseng, 100 grams of betel, 150 grams of agave, 100 grams of coriander root, 50 grams of sheep ear garlic, 120 grams of safflower, 100 grams of silkworm, 150 grams of turban 100 grams of strong gluten grass, 100 grams of Buddha belly flower, 80 grams of dried blood;

[0017] (2) Crumble frankincense and dried blood into fine powder, pass through a 120-mesh sieve, and set aside;

[0018] (3) Put calabash vine, Eucommia ulmoi...

experiment example

[0021] Experimental example Effect of the pharmaceutical composition of the present invention

[0022] 1. General information In this group, 100 children with infected wounds after fracture surgery were divided into an observation group of 60 cases and a control group of 40 cases. The children in the observation group were between 3 and 8 years old, with an average of 6.5 years old; the infected wound area ranged from 0.4cm×2.2cm to 3.0cm×8.5cm, and 10 cases had skin and soft tissue defects with purulent secretions; no bone, Tendons and nerves are exposed. The age of the control group was between 2.5 and 9 years old, with an average of 6.2 years old; the infected wound area ranged from 0.3cm×2.0cm to 3.7cm×9.5cm, including 9 cases of skin and soft tissue defects with purulent secretions; no bone, tendon, Nerve exposure. All children suffered from infection after fracture operation. There was no significant difference in the general data of the two groups of patients (P>0.05...

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating wound infection after pediatric fracture. The pharmaceutical composition is prepared from the following substances in parts by weight: 1-10 parts of olibanum, 1-10 parts of centella asiatica, 10-20 parts of calabash gourd, 5-15 parts of eucommia ulmoides, 1-10 parts of liquorice, 1-10 parts of folium artemisiae argyi, 5-15 parts of siberian walking fern, 5-15 parts of sanguisorba officinalis, 1-10 parts of rosa cymosa leaves, 10-20 parts of honeysuckle, 1-10 parts of field horsetail, 5-15 parts of pseudo-ginseng, 5-15 parts of piper hancei, 10-20 parts of ottelia alismoides, 1-10 parts of rhizoma imperatae, 1-10 parts of liparis japonica, 5-15 parts of flos carthami, 1-10 parts of bombyx batryticatus, 10-20 parts of sculellaria barbata, 5-15 parts of Chinese clovershrub root, 5-15 parts of chien briggsia herb and 1-10 parts of resina draconis. The pharmaceutical composition disclosed by the invention has a significant effect on treatment of the wound infection after pediatric fracture, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a pharmaceutical composition for treating postoperative wound infection in children. Background technique [0002] Young children are prone to fractures due to hyperactivity and immature motor skills. Fracture surgery resulted in an infected wound. Delayed union or nonunion of the original fracture wound is one of the difficult problems in orthopedic clinical treatment. Moreover, infected wounds make the patient's body resistance low, the skin repair ability declines, and the tissue regeneration ability is poor. If the wound surface does not heal for a long time or is not treated in time, it will bring about adverse consequences such as pain, infection, and progressive necrosis. In particular, the development of various systems of young children is immature, their immunity and resistance are far lower than those of adults, and their recovery speed is slower. Therefore, it is urgent to...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P17/02A61P31/00A61P29/00A61K35/64
CPCA61K9/0014A61K9/06A61K36/11A61K36/185A61K36/23A61K36/258A61K36/282A61K36/286A61K36/324A61K36/355A61K36/46A61K36/48A61K36/484A61K36/539A61K36/67A61K36/738A61K36/739A61K36/88A61K36/888A61K36/889A61K36/896A61K36/898A61K36/899A61K47/44A61K2300/00
Inventor 赫文波
Owner 邳州市润宏实业有限公司
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