Absorbable intraosseous fixing device with biological activity and plasticity and forming method

A bioactive, fixation device technology, applied in the direction of internal fixator, fixator, internal bone synthesis, etc., can solve the problems of prone to secondary fractures, delayed bone healing process, uneven stress distribution, etc., to reduce sterility. Sexual inflammation, reduce patient pain, improve the effect of mechanical strength

A bioactive, fixation device technology, applied in the direction of internal fixator, fixator, internal bone synthesis, etc., can solve the problems of prone to secondary fractures, delayed bone healing process, uneven stress distribution, etc., to reduce sterility. Sexual inflammation, reduce patient pain, improve the effect of mechanical strength

CN104546103AInactive Publication Date: 2015-04-29深圳市博立生物材料有限公司
6 Cites 8 Cited by

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Absorbable intraosseous fixing device with biological activity and plasticity and forming method
  • Absorbable intraosseous fixing device with biological activity and plasticity and forming method
  • Absorbable intraosseous fixing device with biological activity and plasticity and forming method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0099] A bioactive and plastic absorbable bone internal fixation device for clavicle fractures, comprising: an arc-shaped bone plate and bone screws matched with the bone plate, the bone plate is provided with a fixing hole; A protective layer is sprayed on the surface, and the thickness of the protective layer is 0.02 μm.

[0100] The bone plate is made by compounding polylactic acid (PLA) and hydroxyapatite (HA). The molecular weight of polylactic acid (PLA) is 100,000-200,000, and the particle size of hydroxyapatite (HA) is 0.5 μm. In terms of percentage, the total amount of polylactic acid (PLA) accounts for 90% of the total weight of the composite material, and hydroxyapatite (HA) accounts for 10% of the total weight of the composite material.

[0101] The above-mentioned molding method of the bioactive and plastic absorbable bone internal fixation device for clavicular fractures comprises the following steps:

[0102] (1) Take an appropriate amount of polylactic acid (P...

Embodiment 2

[0112] A bioactive and plastic absorbable bone internal fixation device for long bone shaft fractures, including: T-shaped bone plate and bone screws used in conjunction with the bone plate, intramedullary nails, fracture dislocation fixation equipment and bone pins, the bone set Fixing holes are arranged on the plate; bone screws, intramedullary nails, bone needles and fracture and dislocation fixing devices are all fixed through the fixing holes. A protective layer is provided on the surface of the bone plate, and the thickness of the protective layer is 30 μm.

[0113] The bone plate is made of polylactic-co-glycolic acid (PLGA), polyglycolic acid (PGA), and β-tricalcium phosphate porous ceramics (β-TCP). Poly-lactic-co-glycolic acid (PLGA) 1. The molecular weight of polyglycolic acid (PGA) is 80-1.5 million, and the particle size of β-tricalcium phosphate porous ceramics (β-TCP) is 10-13 μm. According to weight percentage, polylactic acid-glycolic acid copolymer (PLGA), T...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Particle sizeaaaaaaaaaa
Thicknessaaaaaaaaaa
Login to View More

Abstract

The invention relates to the field of biological medical apparatus and instruments, and particularly relates to an absorbable intraosseous fixing device with biological activity and plasticity and a forming method. The absorbable intraosseous fixing device comprises a bone fracture plate and bone screws, wherein the bone fracture plate is provided with fixing holes and is made by a biologically absorbable high polymer material and biologically active ceramics or biologically active glass; the biologically absorbable high polymer material is 70-95% of the total weight of a composite material in parts by weight, and the biologically active ceramics or biologically active glass takes up 5-30% of the total weight of the composite material; the biologically absorbable high polymer material is selected from one or more of polylactic acid, polycaprolactone, polylactic acid-glycolic acid copolymer, polyglycolic acid, polyhydroxyalkanoate and polyhydroxybutyrate, and the molecular weight is 100,000 to 2,000,000. The absorbable intraosseous fixing device is good in biocompatibility, and can be degraded after the device is implanted in the body; meanwhile, aseptic inflammation caused in the course of material degradation can be reduced, and the pain of a patient can be alleviated; in addition, the personalized customization can be realized.

Description

technical field [0001] The invention relates to the field of biomedical devices, in particular to a bioactive and plastic absorbable bone internal fixation device and a molding method. Background technique [0002] Metal fracture internal fixation materials (stainless steel, cobalt-based alloys, titanium alloys, etc.) have achieved great success in the treatment of fractures. In terms of treatment, metal internal fixation is still the most widely used internal fixation material. The reasons are that it has high strength, mature technology, low cost, can be easily changed in shape to adapt to the outline of bone, and is easy to preserve. However, there are significant defects in rigid metal internal fixation: ①The mechanical compatibility between metal material and bone tissue is not good. This mismatch of mechanical properties will lead to uneven stress distribution, causing relative movement between the implant and the bone under load, which directly leads to loosening or...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
29 Apr 2015
Publication
CN104546103A
IPC
A61B17/80; A61B17/86; A61B17/72; A61L31/12; A61L31/16; A61L31/14
CPC
A61B17/8052; A61B17/72; A61B17/808; A61B17/86; A61B17/8625; A61B17/866; A61B2017/00526; A61B2017/00831
Inventors
张平; 宋小文