31results about How to "Osteoinductive" patented technology

The invention relates to a magnesium phosphate bone cement. The bone cement includes a powder and a liquid. The liquid-solid ratio of the liquid to the powder is 0.1-0.5ml / g. The powder is composed of the following components: 32-70wt % phosphate, 28-65wt% magnesium oxide and 1-15wt% silicon-containing compound; preferably, the powder also includes ammonium dihydrogen phosphate and degradable adhesion-promoting material, and the ammonium dihydrogen phosphate accounts for phosphate 5‑30% by weight of the total amount. During the degradation process, the bone cement of the present invention will produce a porous gel layer rich in Si-O-Si, which can enhance protein adsorption, promote extracellular response, reduce the freeness of metal ions, thereby improving the bioactivity of bone cement. compatibility. The bone cement of the invention also has early high strength and excellent bonding performance, and can be used for bone bonding, reinforced screw fixation and the like in addition to traditional bone filling.

An artificial bone is prepared from polylactic acid (1.5-2 wt. portions), hydroxy apatite (1-1.5) and decalicified bone matrix (0.5-1) through emulsion mixing method where ethyl acetate and absolute alcohol are used as solvent. Its advantages include no damage to human body and good bone transfer and induction actions. It can be used for treating dysostosis and nonunion.

The invention relates to an ejected aquagel of sodium alginate crosslink dope, with dual-phase calcium-phosphorus particle, wherein it is prepard from aldehyde group sodium alginate, dope, and dual-phase calcium-phosphorus particles; the mass percentages of each material are: aldehyde group sodium alginate at 5-20%; dope at 10-30%; and dual-phase calcium-phosphorus particles at 50-70%. The invention also discloses a relative preparation and application, wherein said inventive product is characterized in that: (1), the materials are safe and innocuous; (2), it can provide best physical chemical environment for regenerating and rebuilding skelton, with better biological compatibility and adjustable physical property and biological degrade function; (3), the material can stuff the skeleton damage in any shape, to contact the around organism, with simple operation.

The invention belongs to the field of bone tissue replacement materials, and in particular relates to a method for preparing a chitosan-graphene-hydroxyapatite composite material as a bone tissue replacement material. The invention provides a method for preparing a bone tissue replacement material. The method comprises sequentially: preparing hydroxyapatite / chitosan slurry, preparing melamine sponge loaded with hydroxyapatite / chitosan slurry, sintering and molding, loading The reduction of graphene oxide and graphene oxide; the method for the preparation of the melamine sponge of the loaded hydroxyapatite / chitosan slurry is: the melamine sponge is immersed in the hydroxyapatite / chitosan slurry by extrusion compaction Amine sponge Fill the pores in the melamine sponge with the slurry, then take it out and vacuum dry it to get the melamine sponge loaded with nano-hydroxyapatite / chitosan; the vacuum temperature is 40-80°C, and the vacuum degree is 60-90KPa . The obtained bone tissue replacement material has a porous structure, has high mechanical strength and porosity, and can meet the requirements of the bone tissue replacement material.

A preparation method of medical pure magnesium surface coupling load inducing bone growth traditional Chinese medicine coating relates to a preparation method of medical pure magnesium surface coating. According to the preparation method provided by the invention, a series of biological problems, such as hemolysis, inflammation and the like, caused by the fact that the existing medical magnesium and magnesium alloy materials are degraded quickly in the physiological environment, and the technical problems that potential hazard is generated on tissue growth and repair are solved. The preparation method comprises the steps: 1, performing surface pretreatment on a pure magnesium test sample; 2, preparing micro-arc oxidation electrolyte; 3, performing ultrasonic micro-arc oxidation treatment; and 4, performing aftertreatment. The coating composite material prepared by the method is formed by compounding pure magnesium and coupling modifying self-assembling traditional Chinese medicine coating on the surface of the pure magnesium, and has the characteristics of metal materials and ceramic materials; an ultrasonic-micro-arc oxidation composition technology and a self-assembling technology of the preparation method are green environmentally-friendly processes, so low production cost can be guaranteed well; furthermore, the prepared material has excellent bone inducing property, corrosion resistance and antibacterial property.

The invention discloses a yttrium-containing amorphous alloy material and a preparation method thereof. The alloy is characterized in that: the alloy structure is amorphous, and is composed of the following components by mass percent: 0.3‑6% Y, 0.5‑6% Y 2% Zn, 0.5-2% Ca, the balance is magnesium and impurity elements introduced during the preparation process in a small amount. Compared with the prior art, the yttrium-containing amorphous magnesium alloy material of the present invention has the advantages that (1) it has superior corrosion resistance, and its corrosion resistance is even 4 times that of some existing magnesium alloys, and can be used in orthopedics The growth recovery cycle provides effective stress support without destructive corrosion degradation; (2) has superior mechanical properties; (3) not only has good biocompatibility, but also has osteoinductivity, which can make the fracture growth recovery cycle shorten.

The invention discloses a bracket material of bone tissue engineering of self-promoting vascularizing strontium-doped calcium polyphosphate and a preparation method. The bracket material mainly consists of strontium polyphosphate and calcium polyphosphate according to mol ratio of strontium and calcium of 0.5-10% and is in a porous block structure. The preparation method comprises the following steps of: proportioning the strontium polyphosphate and calcium polyphosphate according to the mol ratio of strontium and calcium determined by the bracket material of bone tissue engineering, adding 30-50% of a cavity-inducing agent based on the proportional weight of the strontium polyphosphate and calcium polyphosphate, preparing blocks with designed shapes after adequately mixing; sintering for1-3 hours at 820-950 DEG C, and cooling along with the sintering device to environmental temperature, thus, the bracket material having the self-promoting vascularizing function is obtained. The bracket material of the bone tissue engineering disclosed by the invention has favorable self-promoting vascularizing function, good biodegradability, bone conductivity, bone inductivity and biocompatibility, and is reliable for repairing and treating the bone for bone defect patients.

The present invention discloses a method for preparing bone grafting material by using velvet deerhorn and deer's bone as raw material and bone grafting material prepared by adopting said preparation method. It is characterized by that said invention utilizes the extract of velvet deerhorn and deer's cancellous bone to prepare bone-grafting material, its resource is rich and its application is safe, and said bone-grafting material contains several growth factors and velvet deerhorn polypeptide, so that it has obvious bone induction action, and can obtain extensive application.