Preparation method of carbon quantum dot and application thereof

A technology of carbon quantum dots and carbon sources, which is applied in the field of fluorescent quantum dot preparation, can solve problems such as insufficiently high fluorescence quantum yields of carbon quantum dots, cumbersome synthesis methods, and harsh conditions, and achieve good imaging and tracing effects and application prospects. The effect of low cost and mild reaction conditions
CN104592993AInactive Publication Date: 2015-05-06UNIV OF ELECTRONIC SCI & TECH OF CHINA
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
UNIV OF ELECTRONIC SCI & TECH OF CHINA
Publication Date
2015-05-06
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method of carbon quantum dot by using chitosan through microwave, and application of the carbon quantum dot in biology medicine field. The method comprises the following steps that the high molecular weight chitosan is taken as the raw material, the microwave high temperature one-step synthesis method is adopted for preparing the carbon quantum dot with high quantum yield, and the surface passivation for the hydrophilia polyethylene glycol (PEG) is assisted to obtain the biology / medicine imaging quantum dot with high imaging capability, good water solubility, low cost and light-resistance quenching capability. The raw material is easy to obtain and the preparation process is simple and convenient, the carbon quantum dot has excellent optical property and is specially applied to the biomedical tracking and imaging field.
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Description

technical field

[0001] The invention relates to a method for preparing fluorescent quantum dots for cell imaging, group modification and its application in the field of biomedicine, belonging to the field of nanomaterial preparation and application. Background technique

[0002] Quantum dots refer to semiconductor nanocrystals whose radii are smaller than or close to the laser Bohr radius, and are nanometer-sized particles with unique optical and electrical properties. As a fluorescent material, quantum dots are widely used in the field of biomedicine for fluorescent labeling and imaging of cells and living organisms. In the past, organic chemical dyes (such as FITC, Cy5, Hoechst 33342, etc.) and semiconductor quantum dots based on heavy metals (such as CdTe, CdSe, etc.), which were widely used in the field of biomedicine, gradually exposed insurmountable limitations, mainly reflected in the following Several aspects: (1) Organic reagents or semiconductor quantum dots conta...

Claims

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