Detection method for musk Xintongning preparation

A musk heart Tongning and detection method technology, applied in the direction of measuring devices, instruments, scientific instruments, etc., can solve the problems of poor layering, no corydalis, long operation time, etc., to achieve enhanced quality control means, more color spots , good separation effect

Active Publication Date: 2015-09-09
山东宏济堂制药集团股份有限公司
View PDF2 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] (3) Identification of ginseng: the process is complicated, the process of washing with n-butanol sodium hydroxide and washing with water emulsifies seriously, and it cannot be separated well after being left overnight, and the operation time is very long;
[0015] (4) There is no identification of Yanhusuo
[0017] (1) Poor detection and poor resolution of other components except tetrahydropalmatine

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Detection method for musk Xintongning preparation
  • Detection method for musk Xintongning preparation
  • Detection method for musk Xintongning preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1 A kind of detection method of Shexiang Xintongning preparation

[0062] 1. Identification

[0063] (1) Identification of artificial musk: Take 2.5g of Shexiang Xintongning preparation, grind it finely, add 20ml of ether, ultrasonicate for 15 minutes, filter, and add 1mL of 2,4-dinitrate to the residue left after the filtered filtrate evaporates to dryness Base phenylhydrazine test solution, put it aside for 30 minutes, add acetonitrile to dissolve and transfer it to a volumetric flask, shake, filter, and the filtrate is used as the test solution; in addition, take muscone hydrazone reference substance, add acetonitrile and configure it to contain The solution of muscone hydrazone 0.2mg, as the reference substance solution, according to high performance liquid chromatography, octadecylsilane bonded silica gel is used as filler; methanol-0.1% phosphoric acid is used as mobile phase, and the detection wavelength is 365nm;

[0064] Get need testing solution an...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
Login to view more

Abstract

The invention relates to a detection method for a musk Xintongning preparation. The detection method comprises identification for artificial musk, identification for storax, ligusticum wallichii and borneol, identification for ginseng, identification for corydalis tuber, detection for tetrahydropalmatine, and analysis for characteristic fingerprints and mass spectrum of the musk Xintongning preparation. According to the invention, all the herbal medicines of the musk Xintongning preparation are identified, and the characteristic fingerprints of the musk Xintongning taking tetrahydropalmatine as the reference substance are determined. The detection method provided by the invention is good in stability, easy to operate, small in loss and high in accuracy; the shape of the chromatographic peak meets the detection requirements well, and is symmetrical; ligusticum wallichii, storax and borneol are identified by using the same thin layer plate, and are identified at the same time, so that the specificity is strong; the identification for ginseng can meet the conventional detection standard; meanwhile, the preparation time of a test sample is greatly shortened, and the detection efficiency is improved; the developing spots during identification for corydalis tuber are abundant, so that environment protection purpose is achieved; the mass spectrum identification adopted in the invention is special technology for the musk Xintongning preparation.

Description

technical field [0001] The invention relates to a detection method of Shexiang Xintongning preparation, which belongs to the field of traditional Chinese medicine detection. Background technique [0002] In the prior art, the identification and detection methods of Shexiang Xintongning preparation are: [0003] Identification: (1) Identification of artificial musk: extraction with ether, silica gel G thin-layer plate, development with toluene, and color development with dinitrophenylhydrazine test solution; [0004] (2) Styrax identification: ether extraction, silica gel G 254 TLC plate petroleum ether-n-hexane-ethyl formate-formic acid development, UV light inspection; [0005] (3) Identification of Rhizoma Chuanxiong: extract with ether, expand with n-hexane-ethyl acetate on a silica gel G thin-layer plate, and inspect under ultraviolet light; [0006] (4) Borneol identification: ethyl acetate extraction, PEG-20W is the gas chromatography identification of stationary ph...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/90G01N30/06
Inventor 张桥张京华宋骁毕丽娟李海燕李樱武勇李秀凤
Owner 山东宏济堂制药集团股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap