Application of a lignan compound

A technology of lignans and compounds, which is applied in the field of application of lignans and can solve problems such as no research reports on lowering blood lipids
CN105030802BActive Publication Date: 2020-07-07HAINAN MEDICAL COLLEGE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
HAINAN MEDICAL COLLEGE
Publication Date
2020-07-07

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Abstract

The invention belongs to the field of biological medicine, and specifically relates to an application of a lignan compound in the preparation of drugs for reducing blood fat. The disclosed triterpene lignan compound is (-)-syringaresinol-4-O-glucoside, and the structural formula of the lignan compound is represented by the formula (I). The provided compound can prominently inhibit lipid accumulation in-vitro, is capable of obviously reducing the cholesterol and triglyceride in the animal blood of a hyperglycemia model, and has a prominent effect on reducing blood fat. The lignan compound can be used as a novel drug for reducing blood fat, and can be used to treat hyperglycemia, and the drug is user-friendly.
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Description

technical field

[0001] The invention belongs to the field of biochemical medicine, and in particular relates to the application of a lignan compound. Background technique

[0002] Due to abnormal fat metabolism or operation, one or more lipids in plasma are higher than normal, which is called hyperlipidemia. Lipids that are insoluble or slightly soluble in water must be combined with proteins to exist in the form of lipoproteins. Therefore, hyperlipidemia is often hyperlipoproteinemia. Hyperlipidemia is generally manifested as an increase in plasma cholesterol (TC) or triglyceride (TG) levels or both, which can directly cause some diseases that seriously endanger human health, such as atherosclerosis, coronary heart disease, etc. Cardiovascular disease. At present, the use of lipid-lowering drugs is an effective measure for the prevention and treatment of hyperlipidemia. There are many chemical drugs on the market, including statins, fibrates, etc. Although these chemical...

Claims

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