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Medicine composition for treating pancreatitis and application thereof

A composition and technology of pancreatitis, applied in the field of medicine, can solve the problems of high manufacturing cost and achieve the effect of low cost, significant curative effect, safety and no side effects

Inactive Publication Date: 2015-11-18
QINGDAO JINZHI HIGH NEW TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drug is more expensive to manufacture

Method used

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  • Medicine composition for treating pancreatitis and application thereof
  • Medicine composition for treating pancreatitis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] The preparation of embodiment 1 Chinese medicine capsule

[0015] Herbal medicine prescription: Guangdilong 1.9kg, Anemarrhena 2.1kg, Dangpi ginseng 2.1kg, Albizia juniper 2.2kg, Trichosanthes 1.5kg, Baiweiye 1.5kg, Xuanming powder 0.6kg, oyster 2.6kg, green fruit 1.3kg.

[0016] Preparation process: Weigh the raw materials of the above-mentioned Chinese medicinal materials of the prescribed amount, add 12 times the amount of water, soak for 15 hours, and then decoct three times, decoct for 2 hours for the first time, filter out the medicinal liquid for later use; add 8 times the amount of water for the second time , decocted for 1.5 hours, filtered out the medicinal solution for later use; added 8 times the amount of water for the third time, decocted for 1 hour, and filtered the medicinal solution for later use; combined three decoctions, filtered, and collected the filtrate; the filtrate was concentrated to a thick paste, Baking at low temperature for 7 hours, pulver...

Embodiment 2

[0017] The preparation of embodiment 2 Chinese medicine capsules

[0018] Herbal medicine prescription: Guangdilong 2.3kg, Anemarrhena 2.3kg, Dangpi ginseng 2.3kg, Albizia juniper 2.3kg, Trichosanthes 1.5kg, Baiweiye 1.5kg, Xuanming powder 0.6kg, oyster 3.0kg, green fruit 1.0kg.

[0019] Preparation process: Weigh the raw materials of the above-mentioned Chinese medicinal materials of the prescribed amount, add 10 times the amount of water, soak for 16 hours, then decoct three times, decoct for 2 hours for the first time, filter out the medicinal liquid for later use; add 9 times the amount of water for the second time , decocted for 1.5 hours, filtered out the medicinal solution for later use; added 8 times the amount of water for the third time, decocted for 1 hour, and filtered the medicinal solution for later use; combined three decoctions, filtered, and collected the filtrate; the filtrate was concentrated to a thick paste, Baking at low temperature for 8 hours, pulverizi...

Embodiment 3

[0020] Example 3 Study on the Curative Effect of Chinese Medicine Extracts on Acute Pancreatitis Model Rats

[0021] Clean-grade male SD rats with a body weight of 180-200 g were given free access to food and water, and were used for experiments after adaptive feeding for 2 weeks. All rats were fasted for 12 h before the experiment and had free access to water. 8 rats were randomly selected as the normal control group; other rats were divided into model control group and Chinese medicine high-dose and low-dose groups, with 8 rats in each group, and the acute pancreatitis model was replicated as follows: Intraperitoneal injection of L -Arginine (20% L arginine solution prepared with deionized water when used), each dose is 2.5g / kg, with an interval of 1 hour, to induce acute pancreatitis model. 6 hours after the second injection of L-arginine, drug therapy was started, and the dry paste powder prepared in Example 1 was administered into the stomachs of the high and low dose gr...

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Abstract

The invention discloses a medicine composition for treating pancreatitis and an application thereof. The composition is prepared from, by weight, 16-23 parts of pheretima aspergillum, 18-25 parts of rhizoma anemarrhenae, 18-25 parts of holothuria leucospilota, 18-25 parts of cortex albiziae, 11-20 parts of snakegourd fruits, 11-20 parts of bay leaves, 4-8 parts of compounds of glauber-salt and liquorice, 22-30 parts of oysters and 9-18 parts of Chinese lives. The selected medicinal materials are proper in compatibility, the remarkable curative effect is achieved for treating pancreatitis, the treatment course is short, effect taking is quick, and no relapse is caused after pancreatitis is cured. The medicine composition is safe, free of toxic and side effects, easy to take and low in cost, and can achieve the purpose of treating both symptoms and root causes.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating pancreatitis and its application. Background technique [0002] Pancreatitis is a disease of the pancreas caused by the autodigestion of trypsin. Under normal circumstances, pancreatic juice contains inactive pancreatic zymogen in its glandular tissue, and pancreatic juice continuously flows into the duodenum through the common bile duct through the Oddi's sphincter along the pancreatic duct. The mucous membrane of the upper duodenum secretes a kind of enterokinase. Under the action of the two, the pancreatic zymogen begins to transform into a highly active digestive enzyme. If the outflow tract is blocked and the excretion is not smooth, pancreatitis can be caused. Manifestations: pancreatic edema, hyperemia, or hemorrhage, necrosis. Clinically, symptoms such as abdominal pain, abdominal distension, nausea, vomiting, and f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P1/18A61K35/62A61K35/618A61K33/04
Inventor 不公告发明人
Owner QINGDAO JINZHI HIGH NEW TECH
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