The invention discloses a processing method of an anticancer and tumor eliminating concentrated pill. According to a formula, the anticancer and tumor eliminating concentrated pill is composed of fried toad skin, taxus chinensis, camptotheca acuminate, Yunnan notoginseng, sophora flavescens, fried semen strychni, fried cooked rhubarb with wine, fried cyperus rotundus with vinegar, radix rehmanniae preparata, fried coptis chinensis with ginger, platycodon grandiflorum, pheretima aspergillum, airpotato yam rhizome, gynostemma, paris vietnamensis, fried centipede with wine, fried leech with vinegar, eupolyphaga, gecko, spina gleditsiae, honeysuckle, fried entire angelica sinensis with wine, fried pinellia ternata with ginger, radix codonopsis from wutai county in the xinzhou area, unprocessed astragalus, radix ophiopogonis, lucid ganoderma, Guangxi radix curcumae, fried achyranthes bidentata with yellow rice wine, salvia miltiorrhiza, rhizoma curcumae, Yunnan tuckahoe, radix aconite lateralis preparata, steamed fructus schisandrae with vinegar, radix scrophulariae, polyporus umbellatus, lobelia chinensis, houttuynia cordata, orange peel, unprocessed liquorice, fried common yam rhizome and natural honey. The processing method comprises the following steps: decocting the medicinal materials, concentrating the liquid, smashing raw materials and the like to prepare the concentrated pill. The concentrated pill is suitable for treating various cancers such as liver cancer, lung cancer, stomach cancer, esophageal cancer and lymph cancer, remarkable in curative effect, free of toxic or side effect and capable of realizing anti-metastasis recurrence, prolonging the lifetime of a patient and improving the life quality.