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Traditional Chinese medicine preparation for preventing and treating hypertensive diseases and method for preparing traditional Chinese medicine preparation

A traditional Chinese medicine preparation and a technology for hypertension are applied in the field of traditional Chinese medicine preparations for preventing and treating hypertension and their preparation fields, and can solve the problems of large blood pressure fluctuation, drug resistance, adverse reactions and the like

Inactive Publication Date: 2015-12-02
王清海
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, Western medicine treatment is based on diuretics plus antihypertensive drugs (such as β-blockers, calcium ion antagonists, angiotensin converting enzyme inhibitors, nitrates and α-blockers). Diuretics can affect the metabolism of blood sugar, blood lipids, and blood uric acid, so they should be used with caution. Other antihypertensive drugs also have the following shortcomings: ①. The use of certain antihypertensive drugs may lead to drug resistance; ④, few targets and pathways of action; ⑤ The efficacy of a single drug is not good, and combination drugs are required
That is to say, most traditional Chinese medicines are used to treat the liver-yang hyperactivity type, and there are few Chinese medicines for the qi-deficiency and phlegm-turbid type with a high incidence.

Method used

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  • Traditional Chinese medicine preparation for preventing and treating hypertensive diseases and method for preparing traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for preventing and treating hypertensive diseases and method for preparing traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for preventing and treating hypertensive diseases and method for preparing traditional Chinese medicine preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Example 1 The composition of the active components of the Chinese medicine mixture for preventing and treating hypertension described in this example is as follows: 21 parts of Radix Astragali, 11 parts of Gastrodia elata, 11 parts of Pinellia fragrans, 16 parts of Poria cocos, 16 parts of Alisma, 7 parts of Huajuhong , Chuanxiong 11 parts.

[0041] The preparation method of the Chinese medicine mixture is as follows: decoct the above 7 flavors twice, add 12 times the weight of the medicinal material each time, decoct for 1.5 hours, filter, combine the filtrates, and concentrate to a relative density of 1.25-1.35 (60°C). Clear ointment, standby; Get above-mentioned clear ointment, merge, add antiseptic and sucrose according to the regulation under " Chinese Pharmacopoeia " appendix IJ mixture item, or add other flavoring agents (such as stevioside or aspartame, etc.), add water to Prescribed amount, adjust the pH of the liquid medicine to 4.5~5.5, boil, refrigerate, fil...

Embodiment 2

[0042] Example 2 The composition of the active ingredients of the traditional Chinese medicine granules for preventing and treating hypertension described in this example is as follows: 20 parts of Radix Radix Rhizoma Radix, 10 parts of Gastrodia elata, 10 parts of Pinellia chinensis, 15 parts of Poria cocos, 15 parts of Alisma, Huajuhong 6 parts, 10 parts of Chuanxiong.

[0043] The preparation method of the traditional Chinese medicine granule is as follows: decoct the above 7 flavors three times, add water 8 times the mass of the medicinal materials each time, decoct for 1 hour, filter, combine the filtrates, and concentrate to a relative density of 1.25-1.35 (60°C). Clear the paste, dry it in vacuum (-0.08MPa; 55~70°C), pulverize it, and obtain the dry extract powder by water extraction, and set aside; take the above dry extract powder by water extraction, add appropriate amount of medicinal dextrin, granulate, pack separately, Instantly.

Embodiment 3

[0044] Example 3 The composition of the active ingredients of the Chinese medicine tablet for preventing and treating hypertension described in this example is as follows: 10 parts of Astragalus, 5 parts of Tianma, 5 parts of Pinellia, 8 parts of Poria cocos, 8 parts of Alisma, 3 parts of Huajuhong parts, 5 parts of Chuanxiong.

[0045] The preparation method of the Chinese medicine tablet is as follows: the above 7 flavors, Gastrodia elata are crushed into fine powder, and set aside; the 6 medicinal materials of Astragalus, Pinellia, Poria, Alisma, Huajuhong, and Ligusticum Chuanxiong are decocted twice, adding 12% medicinal materials each time. Double the water, decoct for 1.5 hours, filter, combine the decoctions, concentrate to a clear paste with a relative density of 1.25-1.35 (60°C), vacuum-dry (-0.08MPa; 55-70°C), pulverize, and extract to dryness Extract powder, spare; take the above medicinal material fine powder and extract dry extract powder with water, calculate ac...

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Abstract

The invention discloses a traditional Chinese medicine preparation for preventing and treating hypertensive diseases and a method for preparing the traditional Chinese medicine preparation. The traditional Chinese medicine preparation comprises, by weight, 10-30 parts of astragalus, 5-15 parts of gastrodia elata, 5-15 parts of prepared pinellia tuber, 8-23 parts of poria cocos, 8-23 parts of rhizoma alismatis, 3-9 parts of pummelo peel and 5-15 parts of ligusticum wallichii. The traditional Chinese medicine preparation and the method have the advantages that effects of spleen invigorating, qi replenishing, dampness dispelling and phlegm dispersing can be realized by the traditional Chinese medicine preparation, and the traditional Chinese medicine preparation can be used for preventing and treating symptoms such as dizziness, headache, heavy sensation of the head, chest distress, excessive phlegm, fatigue and weakness, pale and fat tongue or white and slip tongues, slippery pulse or thin and weak pulse and the like due to hypertensive diseases; the traditional Chinese medicine preparation can be in an optional clinically suitable dosage form including a granule form, a mixture form, a capsule form, a pill form and a tablet form.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine preparation for preventing and treating hypertension and a preparation method thereof. Background technique [0002] Hypertension is a clinical syndrome mainly manifested by increased systemic arterial blood pressure. In the "Guidelines for the Prevention and Treatment of Hypertension in China" (2013), the diagnostic criteria for hypertension are systolic blood pressure (SBP) ≥ 140mmHg and / or diastolic blood pressure (DBP) ≥ 90mmHg in adults aged 18, divided into 1, 2, and 3 according to the level of blood pressure increase class. In my country, the prevalence rate of hypertension has exceeded 18.8%, and it is more common in the elderly over 60 years old. In recent years, its incidence has shown a rapid growth trend. [0003] Hypertension is the most common chronic disease and the most important risk f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/16A61K9/48A61K9/20A61P9/12
Inventor 王清海
Owner 王清海
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