Medical absorbable polyglycolic acid (PGA) operation suture line and preparing method

Abstract

The invention discloses a medical absorbable polyglycolic acid (PGA) operation suture line. The medical absorbable polyglycolic acid (PGA) operation suture line is mainly prepared from first components including, by mass, 8-12 parts of decumbent bugle herb, 6-10 parts of ovateleaf holly bark, 7-12 parts of cortex phellodendri, 5-9 parts of fructus forsythiae, 8-12 parts of flos magnoliae, 12-16 parts of chrysanthemum, 9-14 parts of cyrtomium fortunei, 7-12 parts of cacumen biotae, 8-15 parts of honeysuckle, 4-7 parts of lalang grass rhizome, 5-8 parts of coptidis rhizome, 7-10 parts of houttuynia cordata and 11-15 parts of clinopodium polycephalum, second components including, by mass, 8-12 parts of polyglycolic acid and 4-6 parts of carboxymethyl chitosan, and third components including, by mass, an appropriate amount of dicumyl peroxide, an appropriate amount of sodium alginate and an appropriate amount of azone. The operation suture line is prepared from carboxymethyl chitosan and polyglycolic acid which are high in biodegradability and some common Chinese herbal medicine, has high biodegradability and a good blood coagulation effect, has the functions of resisting bacteria and eliminating inflammation, and avoids wound infection to a great extent.

Description

technical field [0001] The invention relates to the field of medical materials, in particular to a medical absorbable polyglycolic acid (PGA) surgical suture and its preparation method. Background technique [0002] China's medical device market has continued to grow at an annual growth rate of 20-27% in the past ten years, much higher than the 7-10% of the international market, but Chinese products account for less than 3% of the world market, which is as high as the international market. Technical biomedical materials and their products account for more than 40% of the medical device market. Compared with China's biomedical material industry is very weak, there is a serious shortage of raw material suppliers and production bases, and the industrial technology structure is unreasonable. With the development of biomedicine and polymer material science, biodegradable medical materials are attracting more and more attention. [0003] Suture is one of the most basic and import...

AI Technical Summary

Problems solved by technology

[0005] Most of the existing sutures are non-absorbable medical sutures. Removing the sutures after surgery will bring great pain to the patients, which is difficult for most consumers to accept.

However, at present, absorbable sutures are not only expensive, but also only have the function of sutures without certain bactericidal and anti-inflammatory effects, and it is easy to cause wound infection after use