Chinese herbal compound composition for treating lung diseases and preparation method thereof

A technology for lung diseases and compositions, which is applied in the field of traditional Chinese medicine compound compositions for the treatment of lung diseases and its preparation, can solve problems such as many side effects, short drug effect time, and large liver and kidney damage, and achieve reasonable formula and convenient use , quick effect

Active Publication Date: 2016-02-10
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are nifedipine tablets and other drugs for the treatment of COPD with phlegm and blood stagnation in the lung syndrome, but its curative effect on pulmonary arterial hypertension is not very satisfactory
In addition, its drug effect time is short, it has large fluctuations in blood pressure, and it still has negative muscle strength and negative conduction effects, which will also increase the mortality of patients with coronary heart disease.
In addition, the existing western medicines can only cure the symptoms but not the root cause, and these medicines have many side effects, especially serious damage to the liver and kidneys, which only relieve the symptoms and cannot achieve the purpose of a complete cure
[0004] In the prior art, the traditional Chinese medicine composition used to treat chronic obstructive pulmonary disease with phlegm and blood stasis syndrome is disclosed by the specification of Chinese invention patent CN102038841A. The method disclosed in this patent is to extract the raw materials with water, and the astragaloside IV in the raw materials The rate is low, resulting in the loss of active ingredients of traditional Chinese medicine, failing to give full play to the medicinal value of raw materials of traditional Chinese medicine

Method used

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  • Chinese herbal compound composition for treating lung diseases and preparation method thereof
  • Chinese herbal compound composition for treating lung diseases and preparation method thereof
  • Chinese herbal compound composition for treating lung diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, the Chinese medicine compound composition for the treatment of pulmonary diseases

[0028] The traditional Chinese medicine compound composition in this example is made from the following raw materials: 5 parts by weight of raw sun-dried ginseng, 8 parts by weight of Astragalus, 10 parts by weight of Rhizoma Chuanxiong, 3 parts by weight of Scallops, 13 parts by weight of Schisandra chinensis, 4 parts by weight of Tinglizi, and earthworm 20 parts by weight.

[0029] The preparation method of the traditional Chinese medicine compound composition for treating lung diseases comprises the following steps:

[0030] Step 1, add 50% (v / v) ethanol whose weight is 10 times the total weight of the two to raw sun-dried ginseng and Astragalus membranaceus, reflux extraction for 3 times, and reflux extraction for 3 hours each time to obtain the first extract and medicinal residues ; before the decompression recovery, the first extract is filtered; then the ethanol in ...

Embodiment 2

[0034] Embodiment 2, the compound Chinese medicine composition for the treatment of pulmonary diseases

[0035] The traditional Chinese medicine compound composition in this example is made from the following raw materials: 3 parts by weight of raw sun-dried ginseng, 16 parts by weight of Astragalus membranaceus, 4 parts by weight of Rhizoma Chuanxiong, 5 parts by weight of Scallops, 12 parts by weight of Schisandra chinensis, 6 parts by weight of Tinglizi, earthworm 15 parts by weight.

[0036] The preparation method of the traditional Chinese medicine compound composition for treating lung diseases comprises the following steps:

[0037] Step 1, add 70% (v / v) ethanol whose weight is 5 times the total weight of the two to raw sun-dried ginseng and Astragalus membranaceus, reflux extraction once, and reflux extraction for 4 hours each time to obtain the first extract and medicinal residues ; before the decompression recovery, the first extract is filtered; then the ethanol in...

Embodiment 3

[0041] Embodiment 3, the Chinese medicine compound composition for the treatment of pulmonary diseases

[0042] The traditional Chinese medicine compound composition in this example is made from the following raw materials: 10 parts by weight of raw sun-dried ginseng, 5 parts by weight of Astragalus membranaceus, 12 parts by weight of Rhizoma Chuanxiong, 2 parts by weight of Scallops, 15 parts by weight of Schisandra chinensis, 2 parts by weight of Tinglizi, earthworm 30 parts by weight.

[0043] The preparation method of the traditional Chinese medicine compound composition for treating lung diseases comprises the following steps:

[0044]Step 1, add 90% (v / v) ethanol whose weight is 3 times of the total weight of the two to raw sun-dried ginseng and Astragalus membranaceus, reflux extraction 3 times, each time reflux extraction is carried out for 1 hour, and obtain the first extract and medicinal dregs ; before the decompression recovery, the first extract is filtered; then...

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Abstract

The invention discloses a Chinese herbal compound composition for treating lung diseases and a preparation method thereof. The Chinese herbal compound composition is prepared from, by weight, 3-10 parts of sun-dried ginseng, 5-16 parts of astragalus membranaceus, 4-12 parts of rhizoma chuanxiong, 1-20 parts of allium macrostemon, 12-15 parts of schisandra chinensis, 1-35 parts of semen lepidii and 15-30 parts of lumbricus. The preparation method of the Chinese herbal compound composition includes the steps of obtaining a first raw material by extracting sun-dried ginseng and astragalus membranaceus to obtain first thick paste and conducting pressure reduction band drying and smashing on the first thick paste, obtaining a second raw material by mixing decoction dregs with rhizoma chuanxiong, lumbricusm semen lepidii, schisandra chinensis and allium macrostemon to obtain second thick paste and conducting pressure reduction band drying and smashing on the second thick paste, mixing the first raw material, the second raw material and acceptable auxiliaries on pharmacy, and preparing the Chinese herbal compound composition for treating lung diseases. The Chinese herbal compound composition has the advantages that the transfer rate of astragaloside in the raw materials is high, the utilization rate of effective components in traditional Chinese medicine is high, and medical value of traditional Chinese medicine raw materials can be brought into full play.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound traditional Chinese medicine composition for treating lung diseases, and the lung diseases are chronic obstructive pulmonary disease syndrome of lung-kidney qi deficiency and phlegm-stasis obstruction of the lungs. Background technique [0002] Chronic Obstructive Pulmonary Disease (COPD), referred to as COPD, is a disease with high morbidity, disability and mortality. Due to long-term airway obstruction, chronic obstructive pulmonary disease causes alveolar hypoxia and carbon dioxide retention, which promotes pulmonary vasoconstriction, thereby causing pulmonary hypertension (COPD syndrome of phlegm and stasis obstructing the lung). With the increase of pulmonary hypertension, the The burden on the right heart eventually leads to hypertrophy and enlargement of the right heart, eventually forming cor pulmonale. [0003] At present, th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P11/00A61K35/62
Inventor 萧伟李雪峰常秀娟孙晓萍徐振秋米慧娟孙永成吴云丁岗王振中
Owner JIANGSU KANION PHARMA CO LTD
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