Method for producing d-form or l-form amino acid derivative having thiol group

A manufacturing method, amino acid technology, applied in the preparation of organic compounds, biochemical equipment and methods, preparation of thiols, etc., can solve the problems such as not specifically mentioned manufacturing, not reaching the level of manufacturing, etc.
CN105392891AActive Publication Date: 2016-03-09GLYTECH
7 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
GLYTECH
Publication Date
2016-03-09

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention addresses the problem of providing a simple method for producing, at a high yield, an optically active D-form and / or L-form amino acid derivative having a thiol group in a side chain. Provided are: a method for producing an amino acid derivative having a thiol group in a side chain, said method being characterised by producing an intermediate composition that includes D-forms and L-forms of an amino acid derivative which has a thiol group at the beta-position, causing a D- or L-amino acid selective hydrolase to react, and separating the hydrolysed D- or L-amino acid derivatives; and an intermediate therefor.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The present invention relates to a method for producing D-type or L-body amino acid derivatives with thiol groups in their side chains. Furthermore, the present invention relates to an intermediate used in a method for producing a D-form or L-form amino acid derivative having a thiol group in its side chain. Background technique

[0002] In recent years, with the progress of research and development of biomedicine, examples of analyzing the structure and function of synthetic peptides and proteins, and examples of using peptides and proteins as medicines are increasing. Peptides and proteins are composed of amino acids. Except for the side chain substituents of the α-amino acids that make up proteins are hydrogen atoms, the α carbon atoms are asymmetric atoms, so there are mirror images called D-form and L-body. things exist. Peptides and proteins that exist in vivo are composed of L-amino acids. Therefore, to synthesize peptides and proteins that ex...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More