Medical composite alginate dressing containing analgesic drug and preparation method thereof

A technology of alginate and alginate fiber, which is applied in the fields of alginate rayon, medical science, rayon manufacturing, etc., can solve the problems of destroying growth factors, secondary trauma of wounds, dry wounds, etc. Wound healing and wound pain relief effects

Inactive Publication Date: 2016-08-31
SICHUAN KUIXING MEDICAL POLYMER PROD CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional dressings used on wounds mainly play an isolation and antibacterial role, but often lead to dryness of the wound, damage to healthy growth factors, and easy adhesion to new tissue, which will lead to secondary trauma of the wound when the dressing is removed

Method used

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  • Medical composite alginate dressing containing analgesic drug and preparation method thereof
  • Medical composite alginate dressing containing analgesic drug and preparation method thereof
  • Medical composite alginate dressing containing analgesic drug and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] prescription:

[0062]

[0063]

[0064] The preparation method is:

[0065] (1) Prepare the dressing with the prescribed amount of calcium alginate fiber through the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 150g / m 2 ;

[0066] (2) Dissolve lidocaine hydrochloride, gentamicin, sodium chloride, and Tween 20 of the prescribed amount in an appropriate amount of purified water, then add the prescribed amount of glacial acetic acid, stir the resulting solution in the form of nanometer or micron droplets Spray evenly on the surface of the above dressing;

[0067] (3) placing the dressing obtained in (2) in a ventilated drying equipment to dry;

[0068] (4) Cut the dried dressing into a suitable size, package and sterilize, and obtain the medical composite alginate dressing.

[0069] The prepared medical composite alginate dressing can absorb wound exudate, provide a moist healing environment for the wound, and play an an...

Embodiment 2

[0071] prescription:

[0072]

[0073] The preparation method is:

[0074] (1) Prepare the dressing with the prescribed amount of calcium alginate fiber through the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 200g / m 2 ;

[0075] (2) Lidocaine hydrochloride, polyethylene glycol-15-hydroxystearate, hydrochloric acid, and borax are dissolved in purified water to prepare a solution, and the solution is evenly sprayed on the above-mentioned the surface of the dressing;

[0076] (3) The dressing prepared in step (2) is placed in a ventilated drying equipment to dry;

[0077] (4) Cut the dried dressing into a suitable size, package and sterilize, and obtain the medical composite alginate dressing.

[0078] The prepared medical composite alginate dressing can absorb wound exudate, provide a moist healing environment for the wound, and play an analgesic and pain-relieving effect. Cover the affected area with a dressing, which can be su...

Embodiment 3

[0080] prescription:

[0081] Calcium alginate 93 parts

[0082] Lidocaine hydrochloride 5 parts

[0083] Tween 80 2 servings

[0084] The preparation method is:

[0085] (1) Lidocaine hydrochloride and Tween 80 of prescription quantity are dissolved in appropriate amount of purified water;

[0086] (2) Soak the calcium alginate fibers of suitable length and fineness in the solution prepared in step (1) for 30-60 minutes, and then dry them;

[0087] (3) The dressing is prepared by the non-woven acupuncture process, and the weight per unit area of ​​the dressing is about 170g / m 2 ;

[0088] (4) Cut the dressing into a suitable size, package and sterilize, and obtain the medical composite alginate dressing.

[0089] The prepared medical composite alginate dressing can absorb wound exudate, provide a moist healing environment for the wound, and play an analgesic and pain-relieving effect. When in use, the dressing should be covered on the affected part, which can be supple...

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Abstract

The invention discloses a medical composition alginate dressing containing analgesic drug and a preparation method thereof. The medical composition alginate dressing is prepared from, by weight, 50-99.9 parts of alginate, 0.1-25 parts of analgesic drug and 0.01-15 parts of surfactant. Compared with the prior art, the prepared medical composition alginate dressing containing the analgesic drug can be used for the surface of a wound with tissue defects and can be used for filling and supporting defected tissue, absorbing wound exudate and controlling bleeding in an assisted mode so as to promote wound healing and relieve the pain. The dressing which effectively absorbs wound exudate, provides a wet healing environment for the wound, fills and supports the defected tissue, promotes wound healing and relieves the pain of a patient is provided for the injured patient, and is suitable for being popularized in a large range.

Description

technical field [0001] The invention relates to the technical field of wound dressings, in particular to a medical composite alginate dressing containing analgesic drugs and a preparation method thereof. Background technique [0002] The skin and mucous membranes of the human body are the barriers to maintain the stability of the human body environment and prevent the invasion of microorganisms. Damage to the skin and mucous membranes caused by ulcers, trauma, burns and inflammation will cause a series of problems in the body, such as bacterial infection, increased metabolism, Excessive water and protein loss, endocrine and immune system dysfunction, etc., may be life-threatening in severe cases. When the skin and mucous membrane are injured, a suitable dressing should be selected to cover the wound. It can maintain a moist environment for the wound, absorb secretions, relieve pain and control bleeding, thereby promoting rapid wound healing. [0003] The use of dressings is...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44D01F9/04D01F1/02D04H1/46D04H1/492D04H1/42D06B1/02
CPCA61L15/28A61L15/44A61L2300/204A61L2300/402A61L2300/404D01F1/02D01F9/04D04H1/42D04H1/46D04H1/492D06B1/02
Inventor 莫始奎
Owner SICHUAN KUIXING MEDICAL POLYMER PROD CO LTD
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