48 results about "Exudate/transudate" patented technology

The invention discloses an antibacterial dressing based on gallic acid-copper coated gamma-polyglutamic acid and a preparation method and application thereof, and belongs to the technical field of biomedicines.The preparation method comprises the steps that gallic acid and copper chloride dihydrate are dissolved in pure water according to the mass ratio of 3: 1, and stirring is conducted to form a solution I; stirring and reacting the solution I at 40 DEG C for 24 hours, centrifuging, collecting precipitate, washing with pure water, and freeze-drying to obtain gallic acid-copper nanoparticles; the gallic acid-copper nanoparticles and gamma-polyglutamic acid powder are mixed and dissolved in pure water according to the mass ratio of 3: 20, and after freeze drying, gallic acid-copper coated gamma-polyglutamic acid hydrogel powder is obtained. The gallic acid-copper coated gamma-polyglutamic acid hydrogel powder disclosed by the invention can absorb exudate near a wound and is subjected to in-situ gelation to form a hydration layer, so that damage to newborn tissues caused by frequent dressing replacement is avoided; it is verified that the healing promoting effect of the hydrogel can be remarkably enhanced through blue light adjuvant therapy, and the healing speed of infected wounds is remarkably increased.

The invention discloses a concentrated buffer cleaning solution which mainly comprises the following raw materials: disodium hydrogen phosphate, sodium dihydrogen phosphate, Tween-20, propylene glycol, sodium chloride, trihydroxymethyl aminomethane (Tris) and pure water, and the pH value range of the concentrated buffer cleaning solution is 8.9-9.1. According to the invention, a unique lysis and buffer combination system is adopted, and various types of histological and cytological samples and the like can be compatible. A high (pH value) antigen buffer cleaning solution Buffer can be compatible with various histological and cytological sample types including fresh tissues or frozen cells, hydrothorax and ascites, tissue exudate and the like, and free nucleic acid and nucleic acid binding protein in various histological and cytological samples are rapidly and thoroughly separated under the synergistic effect of protease K; then, the separated free nucleic acid is efficiently combined with the antibody under the high-salt condition provided by the adsorption combination buffer solution, and denatured protein, lipid and other impurities are prevented from blocking a probe of a machine.

The invention discloses a preparation method and application of bacterial cellulose and nano-selenium composite antibacterial hydrogel, and the preparation method comprises the following steps: 1, preparing a seleninic acid solution and a gelatin solution, dissolving seleninic acid in the gelatin solution, adding an ascorbic acid solution, and carrying out oxidation-reduction reaction on the ascorbic acid solution and the seleninic acid solution to generate selenium nanoparticles; 2, adding bacterial cellulose into the solution obtained in the step 1, and fully infiltrating for at least 3 hours to obtain bacterial cellulose and selenium nanoparticle composite hydrogel; the bacterial cellulose gel used in the invention has good mechanical properties, is not easy to damage, can be tightly attached to a wound during use, can effectively absorb tissue exudate at the wound, and provides a moist healing environment for the wound; gelatin is used as an end-capping reagent and a stabilizer for preparing the selenium nanoparticles, so that the stability and biocompatibility of the selenium nanoparticles are greatly improved; the preparation method is simple to operate and low in cost and has universality.

The invention provides a device for collecting and cleaning peripheral seepage of a drainage tube after pancreas debridement, and belongs to the technical field of medical instruments. Comprising a collecting structure, negative pressure extraction equipment and a collecting box, and the collecting structure, the negative pressure extraction equipment and the collecting box are communicated; the collecting structure comprises a disc, and a plurality of sliding grooves are formed in the surface of the disc. The skin is extruded by the rolling roller, the skin around the wound is raised at the wound, the height difference is formed between the wound and the surrounding skin raised part and the initial skin state, the arc-shaped guide ring and the pasting protection film rotate in the movable groove to move towards the wound, and the pasting protection film moves to be tightly attached to the surface of the raised skin; when the drainage tube is used, more exudate seeps from the drainage tube body and the wound, the exudate is guided into the exudate collecting barrel along with the arc-shaped guide ring, the exudate in the exudate collecting barrel is collected through the guide holes, contact between the exudate and the adhesive protective film is reduced, and the service time of the adhesive protective film is prolonged.

The utility model discloses a drainage tube orifice seepage ostomy bag capable of preventing a catheter from slipping, and aims to provide the drainage tube orifice seepage ostomy bag capable of preventing the catheter from slipping, which can be matched with the catheter to collect seepage at a wound. The ostomy bag comprises an ostomy bag body, an adsorption disc and a piston switch, a receiving hole is formed in the rear end face of the ostomy bag body, the adsorption disc is installed on the ostomy bag body and corresponds to the receiving hole, a penetrating hole is formed in the front end face of the ostomy bag body, and the piston switch is installed at the lower end of the ostomy bag body. The utility model has the beneficial effects that the device can be matched with a catheter to collect the exudate at the wound, is convenient to release the exudate, can better correspond to the wound, can reduce the sliding of the catheter, can ensure that the catheter is fixed more firmly, and is convenient to observe the collection amount of the exudate.

The present application relates to the technical field of wound repair material, in particular to a chronic wound dressing and a preparation method thereof, the wound dressing is prepared from a first contact layer, an intermediate transition layer and a backing layer which are in direct contact with the wound, through the unique three-layer structure design, a chronic wound dressing with fast healing speed, strong anti-inflammatory and antibacterial properties, high liquid absorption and effective regulation of the microenvironment of the wound is prepared, the first contact layer is in direct contact with the wound, absorbs the exudate, plays an anti-inflammatory and antioxidant role, the intermediate transition layer guides the exudate from the first contact layer to the backing layer through the asymmetric fiber membrane structure on both sides and does not back permeate, the backing layer has a connected microporous structure, has strong air permeability and can absorb a large amount of exudate, provides a humid environment for the wound, inhibits bacterial growth and promotes wound healing, compared with the prior art, has a wide application prospect.

The present invention discloses an anti-inflammatory and healing-promoting electrospun wound dressing, a preparation method and an application thereof, belonging to the technical field of medical dressings, and comprising a double-layer structure of an inner layer and an outer layer; wherein, the outer layer is a hydrophilic nanofiber membrane prepared by single-nozzle electrospinning, and is used to absorb wound exudate; the inner layer is a nanofiber membrane with a core-shell structure prepared by coaxial electrospinning, and the shell layer of the core-shell structure is a hydrophobic material, and is used to guide the exudate to the outer layer; the core layer of the core-shell structure comprises hydrophilic thermosensitive macromolecules, healing-promoting growth factors and anti-inflammatory drugs; the shell layer is hydrophobic, and guides the wound exudate to the outer hydrophilic nanofiber membrane; the gelatin hydrophilic thermosensitive macromolecules in the core layer, when the wound inflammation causes the local temperature to be ≥37°C, the temperature change causes the drug-loaded thermosensitive phase change macromolecules to undergo different degrees of phase change, thereby achieving timely and controllable release of drugs and ensuring the healing of the wound surface.

The invention discloses an antibacterial hemostatic hydrogel loaded with composite nanoparticles, and the antibacterial hemostatic hydrogel loaded with the composite nanoparticles is prepared by the following method which comprises the following steps: (1) synthesizing the composite nanoparticles; the composite nanoparticles are formed by loading a hydrophobic drug on a mesoporous polydopamine nanosphere; (2) synthesizing blank hydrogel; the blank hydrogel is formed by mixing a solution A and a solution B; (3) synthesizing drug-loaded hydrogel; the drug-loaded hydrogel is formed by mixing blank hydrogel and composite nanoparticles; the antibacterial hemostatic gel is formed by the composite nanoparticles and the blank hydrogel through physical mutual left and right, Schiff base reaction and the like, and the antibacterial hemostatic gel has the properties of adsorbing tissue exudate and resisting bacteria, and is suitable for filling and anti-inflammation of brain injury postoperative parts and nerve repair treatment.

The invention relates to a degradable manganous-manganic oxide-tannic acid-polymer composite modified artificial dura mater and preparation thereof, and belongs to the technical field of biological materials. According to the modified artificial dura mater, a spongy collagen biological membrane scaffold beneficial to cell growth and new dura mater tissue generation is provided for a dura mater defect part, and the modified artificial dura mater with good tissue compatibility and degradability is prepared by introducing carboxymethyl chitosan and manganous-manganic oxide / tannic acid. The novel composite artificial dura mater can effectively reduce intracranial infection and leakage of cerebrospinal fluid. The modified artificial dura mater loaded with the antioxidant manganous-manganic oxide / tannic acid nano-composite can effectively remove free radicals in the brain, and the composite modified artificial dura mater has anti-inflammatory and antibacterial functions and can be adhered to the surface of the dura mater after absorbing tissue exudate, water, buffer solution and the like. And can be tightly attached to the dura mater without suturing, and can exert antibacterial and anti-inflammatory activity for a long time.

The application discloses a self-gel powder with functions of rapid hemostasis and lossless removal, a preparation method and application thereof, and belongs to the technical field of biomedical materials. The self-gel powder is prepared from acrylic acid, 3-sulfonic acid propyl methyl acrylic acid potassium salt, quaternary ammonium salt chitosan, tannic acid, calcium ions and methanesulfonic acid deferoxamine through copolymerization, freeze-drying and grinding. The preparation process is simple, and the material has excellent biocompatibility. The powder can be rapidly self-gelated within 30 seconds after contacting with blood or exudate of a wound, and rapid hemostasis is achieved through the cooperation of positive and negative charge adsorption, calcium ion coagulation promotion and physical barrier plugging. Meanwhile, the powder has multiple biological activities such as broad-spectrum antibacterial activity, anti-inflammatory activity and antioxidant activity. After hemostasis is completed, the powder can be gently washed with normal saline to realize lossless removal, thereby avoiding secondary damage. Animal experiments show that the material can effectively promote the healing of a diabetic wound, and provides an integrated and whole-cycle repair scheme for a chronic and difficult-to-heal wound.

The invention provides a preparation method of a composite dressing for inhibiting scars. The preparation method comprises the following steps: 1) preparing a CMC (sodium carboxymethyl cellulose) sponge layer; 2) respectively preparing a silk fibroin electrostatic spinning solution and a polylactic acid / retinoic acid electrostatic spinning solution; and 3) electrospinning the silk fibroin electrostatic spinning solution to the surface of the CMC sponge layer, and then electrospinning the polylactic acid / retinoic acid electrostatic spinning solution to the CMC sponge layer to obtain the sponge-nanofiber-nanofiber composite dressing. All the layers of the composite dressing jointly achieve the effects of optimization of a wound microenvironment, one-way management of wound exudate, directional growth of cells and drug regulation and control, and therefore the purposes of accelerating wound healing and reducing abnormal scar formation are achieved.

The invention discloses a double-cavity anti-leakage drainage tube which comprises an annular self-adhesion base plate and an eccentric funnel connecting plate arranged below a middle through hole of the annular self-adhesion base plate, a near-end double-cavity drainage tube is connected below a ventage of the eccentric funnel connecting plate, a detachable drainage tube is arranged in a first cavity of the near-end double-cavity drainage tube, and a second cavity of the near-end double-cavity drainage tube is connected with a second cavity of the annular self-adhesion base plate. A plurality of side holes are formed in the side wall of the top of the detachable drainage tube, the bottom of the double-cavity drainage tube is connected with a far-end single-cavity drainage tube, a drainage tube clamp is arranged on the far-end single-cavity drainage tube, and the tail end of the far-end single-cavity drainage tube is connected with a negative-pressure or normal-pressure drainage bag. By means of the near-end double-cavity drainage tube, it is avoided that exudate is excessively accumulated in the eccentric funnel connecting disc when a user sideways, the liquid exudating around a wound flowing down from the outer wall of the detachable drainage tube is collected through the second cavity, pollution to clothes and bedding and wound tissue infection caused by exudation around the drainage tube can be effectively reduced, wound healing is promoted, and the wound healing rate is increased. And the times of dressing change and the pain of patients are reduced.

The invention discloses a wound stoma infection prevention nursing device, and belongs to the technical field of medical instruments. The wound stoma infection prevention nursing device comprises a box body, a through hole is formed in the bottom of the box body, gauze is arranged in the through hole, and dressing used for covering a wound is arranged on the outer surface of the gauze; a cavity for containing water-absorbent resin is formed in the box body, and the water-absorbent resin used for absorbing exudate on a wound is placed in the middle of the cavity. The wound stoma infection prevention nursing device further comprises a bag body containing liquid medicine, the bag body is located on the inner wall of the cavity, a liquid outlet is formed in the bag body, the liquid outlet is communicated with a through hole formed in the bottom wall of the cavity, and the through hole is communicated with an annular groove formed in the bottom wall of the cavity. The wound stoma infection prevention nursing device not only can promote wound healing, but also can adsorb exudate and inhibit bacteria from further infecting a wound, the wound treatment capacity is more comprehensive, and further deterioration of the wound can be effectively avoided.

A cleaning system is provided for cleaning a patient's wounds and / or body cavities, particularly the pericardial cavity (PC) and / or pleural cavity. [Solution] The cleaning system includes a carrier unit configured to be movable, an inflow unit including at least one infusion fluid container for containing an infusion fluid, and a collection unit configured to collect exudate from a patient, wherein the carrier unit is configured to house the inflow unit and the collection unit, the inflow unit further includes at least one first weighing unit for measuring the weight of the infusion fluid delivered to the patient, and the carrier unit includes a second weighing unit for measuring the weight of the exudate collected in the collection device.

1. Name of the product in this design: Leak-proof bag. 2. Purpose of this design: A drainage bag to prevent leakage when draining body fluids or tissue exudate from postoperative patients. 3. The key design feature of this product is the shape of the leak-proof bag. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application discloses a preparation method of a composite hydrogel dressing, and is characterized by comprising the following step A1. raw material preparation: 20-40 parts of Astragalus membranaceus, 10-20 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 5-15 parts of Carthamus tinctorius, 3-10 parts of dragon's blood, and 5-15 parts of Bai Zhi. The prepared composite hydrogel dressing has the characteristics of softness and hydrophilicity, can be closely attached to a wound surface of various shapes, and can well cover a flat wound surface or an irregular wound surface, so that a moist healing environment is provided for the wound surface. The moist environment is favorable for the proliferation and migration of wound cells, promotes wound healing, and can also reduce pain during dressing change. The dried hydrogel can form a porous sponge structure, the structure has strong water absorption, can quickly absorb exudates of the wound surface, keeps the wound surface dry, prevents infection caused by accumulation of the exudates, and is convenient for management of the exudates.

A negative pressure wound therapy device can be configured to monitor motion and determine that the device is falling as well as duration and height of the fall. Flat falls and rotating falls can be accurately detected. The device can provide an indication of the fall, including deactivating therapy. The device can monitor the amount exudate removed from a wound and determine whether transition to a low-exudate rate negative pressure wound therapy and suggest such transition. The device can utilize proportional-inte-gral-derivative (PID) control loop to drive a negative pressure source of the device. The PID control loop can utilize different proportional gain and integral gain for different negative pressure setpoint to achieve target pressure quickly and without any large overshoots.

A flushing system comprises: an infusion liquid outlet to connect to a first tube arrangement having a plurality of infusion liquid lumen guiding a flow of infusion liquid from the system to a wound and / or body cavity; an effusion liquid inlet to connect to a second tube having an effusion liquid lumen guiding the effusion liquid from the wound and / or the body cavity to the system; and a flow rate control system to control the flow rate at the infusion liquid outlet. The flow rate control system comprises: a control unit, and a pump device to pump infusion liquid to the infusion liquid outlet at a flow rate adjustable by control signals of the control unit. Each infusion liquid lumen of the first tube arrangement has openings arranged along the first tube arrangement and spaced from one another for leading the infusion liquid into the wound and / or the body cavity.

A biosensor for detecting a biomarker in body fluids, secretions, or exudates is described. The biosensor essentially comprises a first electrode (100a), a second electrode (100b), an electrode coating (200), and a mechanical electrode stabilizer (300). The biomarker is an enzyme that catalyzes a chemical reaction in which one or more components of the electrode coating (200) are chemically altered by the breaking of covalent bonds upon contact with it. The electrode coating comprises a natural or synthetic substrate of the biomarker. The first and second electrodes are electrically conductive and are maintained at a virtually constant and uniform distance from each other by the mechanical electrode stabilizer (300). The exposed conductive surface of at least one of the electrodes is almost completely covered by the electrode coating (200).The biosensor exists in at least one state from the group of states comprising a high-impedance state, in which the electrode coating (200) remains virtually unchanged by the biomarker, and a low-impedance state, in which the electrode coating (200) is chemically altered by the biomarker. A wound diagnostic dressing system incorporating the biosensor of the invention is also provided.

In some embodiments, a negative pressure wound therapy system can detect and classify one or more operational conditions, including detection of a wound bleeding. The system can react to detection of blood by providing an indication, reducing the intensity or stopping therapy, releasing negative pressure, etc. In certain embodiments, the system can detect one or more additional operational conditions, such as change in vacuum pressure, gas leak rate change, exudate flow rate change, water flow rate change, presence of exudate, presence of water, etc. The system can detect and distinguish between different operational conditions and provide indication or take remedial action.

In a surgical drain system formed with two or more branches, exudate flow from a patient's wound is directed between two branches with the respective filling and emptying times determined in order to identify the presence of a blockage in the drain.

The invention belongs to the technical field of medical instruments, and particularly relates to an anorectal postoperative analgesia and hemostasis device which comprises a base plate, an outer tube is mounted on the base plate, an inner tube is mounted on the inner side of the outer tube, an administration assembly is mounted in the outer tube, a wriggling assembly is mounted in the inner tube, and a transmission assembly is mounted at the bottom of the base plate. The wriggling assembly comprises an elastic inner film, an air exhaust sleeve and a transmission sleeve. When medicine needs to be applied to an affected part, the double-end sliding plate moves towards the liquid supply cavity, the first push plate moves away from the second piston, the second push plate moves close to the second piston, and due to the fact that the double-end sliding plate is in sliding fit with the second piston, the second piston does not move. In the process that the double-end sliding plate moves towards the liquid supply cavity, the double-end sliding plate drives the first piston to move towards the liquid supply cavity, negative pressure is generated in the liquid suction cavity, interstitial fluid and blood exuding from the affected part are sucked into the liquid suction cavity, exudates of the affected part are cleared away in time, and the infection risk of the affected part is reduced.

The utility model discloses a soluble hemostatic gauze bandage, belonging to the technical field of medical supplies. The technical scheme thereof includes a substrate layer, a liquid absorbing layer is arranged on the top of the substrate layer, and a hemostatic layer is arranged on the top of the liquid absorbing layer. The substrate layer includes a bottom base layer, an isolation layer is arranged on the top of the bottom base layer, and a connecting layer is arranged on the top of the isolation layer. The hemostatic layer can be quickly dissolved into a highly adhesive jelly after contacting with a bleeding wound surface, effectively covering and blocking damaged capillaries, and at the same time, the blood is concentrated and coagulation factors are activated, thereby achieving the effect of effectively shortening the coagulation time, thereby reducing the pain of nerve endings, and can also effectively prevent adhesion when replaced. At the same time, the liquid absorbing layer can be used in conjunction with the liquid absorbing layer, and the liquid absorbing layer can absorb a large amount of blood or exudate to avoid wound infection and improve the use effect.

This invention provides compositions and methods of treating subjects with wounds. Compositions include dressings comprising a sheet and an adhesive, wherein the adhesive is adhered to the sheet, and wherein the sheet has channels. In some embodiments, the channels comprise two different classes of channels (e.g. liquid channels and air channels). These dressing can be applied to various kinds of skin injuries and remain affixed, protecting the injury from contaminants and at the same time, allowing exchange of exudates on the proximal (injury) side to the distal side and exchange of topical agents applied from the distal side of the dressing to the wound while also allowing exchange of gasses from the injury to the air and air to the wound.

This invention discloses a negative pressure suction device for purulent secretions and inflammatory exudates, relating to the field of medical device technology. Through the combination of a bifurcated connector and a one-way valve, this invention can accurately deliver irrigation fluid to dilute purulent secretions and inflammatory exudates, while also promptly removing the mixed liquid to prevent secretions from remaining on the wound surface. This achieves simultaneous and coordinated irrigation and suction. Furthermore, the one-way valve effectively blocks backflow, preventing contamination of the irrigation fluid source and ensuring the aseptic nature of the irrigation process. The inclined design of the emergency flushing tube quickly clears blockages, ensuring continuous and smooth negative pressure suction. The suction head reduces scratching or irritation to fragile tissues around the wound, and the combination of breathable dressing and fixing wings prevents suction head displacement, reducing the risk of wound bleeding or secondary injury, and improving patient comfort and treatment safety. The standardized interface and interference fit connection facilitate quick installation and disassembly by medical personnel, saving operation time.

The present invention discloses a drainage device. The drainage device includes a first drainage component and a second drainage component. The first drainage component is a columnar structure. The two ends of the first drainage component respectively have a first end face and a second end face. The outer peripheral surface of the first drainage component has a drainage groove, and the drainage groove is also open to the first end face; the second drainage component is a hollow tubular structure with two ends open. The second drainage component is arranged in the direction from the first end face to the second end face through the first drainage component. The drainage device has a good drainage effect and can effectively shorten the postoperative recovery period. The drainage device of the present invention can guide the bloody exudate around the anal wound into the drainage groove and discharge it through the first drainage component; because the second end face is a closed end face, feces can only be discharged through the second drainage component and will not enter the drainage groove. The first drainage component and the second drainage component realize the separation of the anal wound exudate and the feces in the rectum to reduce the chance of anal wound infection.

The utility model discloses a drainage plug for an extraction operation of embedded impacted teeth, which comprises a main body structure and a drainage plug, the side wall of the main body structure is provided with at least one fixing unit used for anchoring the main body structure to the peripheral tissue of the alveolar fossa; one end of the main body structure is provided with an expandable limiting component which is matched with the inner wall of the alveolar fossa to prevent the main body structure from falling off; the main body structure is composed of multiple layers of degradable materials and comprises an outer functional layer and an inner supporting layer. Continuous exudate diversion is achieved through the drainage channel in the main body structure, effusion in a closed environment is reduced, so that the swelling and infection probability is reduced, through the double retention design of the side wall fixing unit and the expandable limiting component, the fitting performance of the drainage plug and an alveolar fossa is enhanced, intraoperative and postoperative disengagement is prevented, and the drainage effect is improved. The multi-layer degradable material is adopted, the outer functional layer rapidly degrades and drains, and the inner supporting layer slowly degrades and supports, so that the device does not need to be taken out, and new tissues are prevented from being torn.

The application discloses a kind of sodium hyaluronate-polyurethane composite hemostatic anti-adhesion sponges for uterine cavity and its preparation method and application, it is related to medical biological composite material technical field;The composite hemostatic anti-adhesion sponge includes sodium hyaluronate crosslinking gel and polyurethane and its porosity is 70%~95%, water absorption is 8~20 times of its own mass, tensile strength is 0.4~1.2MPa, in vitro degradation period is 20~45 days, crosslinking agent residual amount is less than 0.1ug / g, cytotoxicity is less than or equal to 1 level;Sodium hyaluronate crosslinking gel will form soft and lubricious physical barrier after water absorption and expansion, effectively isolate uterine anterior and posterior wall wound, prevent adhesion, provide environment for wound healing;Polyurethane sponge can quickly reach relatively balanced water absorption, help to quickly absorb uterine cavity exudate, keep wound clean, also can provide mechanical support, prevent uterine cavity contracture deformation;Polyurethane is matched with uterine cavity clinical healing period, and degradation product has no toxicity residue.

The invention relates to an implantable artificial kidney and a use method thereof, and the implantable artificial kidney comprises an implantable micro pump, a suction tube piece, a percolate conveying tube, a flow sensor, a pressure sensor, a creatinine urea online detection module, a control chip, a battery, a charging induction coil, an in-vitro charger and a mobile phone APP or a computer terminal, and continuous or intermittent micro-suction is performed on the outer side of the peritoneum for 24 hours to form negative pressure of the outer side of the peritoneum to the inner side of the peritoneum, so that liquid, water and solute (including toxins) on the inner side of the peritoneum convect to the outer side of the peritoneum to form percolate, and the percolate is guided into the bladder through the percolate conveying pipe and is discharged out of the body through normal urination of the human body. According to the implantable artificial kidney and the use method thereof, the design is reasonable, a more effective treatment effect is brought to a renal failure patient, the life quality of the patient can be obviously improved, the life cycle of the patient can be prolonged, and the treatment cost of the patient can be reduced.

The invention discloses an aspirator with a replaceable head, which comprises a main body provided with an aspiration channel, a detachable adsorption part, a connecting structure and an operating handle, the adsorption part is made of a flexible porous material, rapid replacement is realized through a mortise and tenon structure, and the design has dual functions of tissue traction and blood adsorption; exudate in an operation area can be effectively absorbed while enough operation friction force is kept, the head can be replaced immediately when blocked in the operation due to the modular structural design, the operation efficiency is improved, and the novel surgical instrument is particularly suitable for the fine operation field of neurosurgery, plastic surgery and the like.