44 results about "Exudate/transudate" patented technology

A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, including a wound dressing dimensioned for positioning relative to a wound bed of a subject and a subatmospheric pressure mechanism dimensioned to be carried or worn by the subject. The subatmospheric pressure mechanism includes a housing having a control unit adapted to draw a vacuum and a canister associated with the housing. The canister has a collection bag disposed therein, which is in fluid communication with the wound dressing to receive exudates from the wound bed. The collection bag is adapted to expand upon receipt of the fluids and has means to release gas from within the collection bag in connection with operation of the control unit. With this arrangement, the canister is attitude independent, i.e., the canister may be positioned on edge, on its side or on its end etc. while still maintaining operation of the control unit. The collection bag may include a hydrophobic vent or material for releasing the gases. In another embodiment, the collection bag comprises a gas permeable material. The collection bag may include one of pleats or bellows.

A system for subatmospheric pressure therapy in connection with the healing of a surgical wound is disclosed. The system may be portable or semi-portable, thereby providing the subject with the ability to be partially or completely ambulatory through the course of the treatment. The system includes a wound dressing dimensioned for positioning relative to a wound bed of a subject and a portable subatmospheric pressure mechanism dimensioned to be carried or worn by the subject. The subatmospheric pressure mechanism includes a housing, a vacuum source at least partially disposed within the housing and in fluid communication with the fluid conduit, a filter in fluid communication with the vacuum source, and a collection canister for collecting exudates from the wound bed removed under subatmospheric pressure. An elevation member is mounted with respect to the housing. The elevation member is adapted to position the housing and canister at a predetermined orientation when positioned relative to a support surface to minimize a potential of at least one of spillage of the exudates from the canister, clogging of the filter or an inappropriate canister full indication.

A wound dressing can include a backing layer, a facing layer which is permeable for wound exudate and blood and which, when in use, is in contact with the wound, and an absorbent core. The backing layer and the facing layer can be joined together in order to form a pouch. The absorbent core can be located within the pouch and can include at least a first layer and a second layer. The first layer can be located closer to the facing layer than the second layer. The first layer can be configured to provide a flow of liquid predominantly in a direction perpendicular to the extension of the facing layer. The second layer can be configured to provide a flow of liquid predominantly in a direction parallel to the extension of the facing layer.

A stand-alone system for assessing wound exudates from the wound of a patient is described. The system contains functionality to detect, process and report various wound parameters. The system also may make treatment determinations based on these findings. The system may detect one or more physiological values of the wound exudates from the wound of the patient. The system may also compare detected physiological values to predetermined physiological values, in order to obtain a comparison result in real time. The system may include a processor (15) which provides an electronic signal based on the comparison result in which the electronic signal may corresponds to guidelines for treating the wound (3). The system described may be an accessory, which may be used on its own, or in conjunction with other wound treatment devices (9).

The invention discloses a method for preparing a bacterial cellulose slow-release analgesia dressing and relates to the technical field of medical apparatus and instruments and preparation thereof. The method comprises the following steps: uniformly dispersing analgesics in a chitosan solution to obtain a solution A, and mixing an organic solution and a surfactant to obtain a solution B; slowly dropping the solution B into the solution A in a water bath, and performing high-speed stirring to obtain stable water-in-oil (W / O) emulsion; washing the emulsion in a shock chilling water bath, and separating to obtain chitosan slow-release microspheres which have uniform particle size and are encapsulated with the analgesics; and uniformly dripping the chitosan slow-release microspheres on a bacterial cellulose film modified by carboxymethyl cellulose, and performing freeze drying to obtain the bacterial cellulose slow-release analgesia dressing. The method is simple and feasible in preparation process, convenient in operation and low in cost; and the prepared slow-release dressing has the multiple effects of slowly releasing the analgesics, sterilizing, moisturizing, ventilating, absorbing wound exudate and the like and can relieve skin injury and postoperative incisional pain and cure various skin wounds.

The invention discloses a negative pressure wound treatment system based on wound exudate management, comprising a liquid collecting bottle for collecting wound exudate, a negative pressure wound treatment device composed of a negative pressure source and a controller, a wound set for filling and sealing a wound, a wound exudate management module and an alarm, wherein the wound set is communicated with the liquid collecting bottle through a connecting pipe; the wound exudate management module detects and displays the physical parameters of wound exudate in the liquid collecting bottle and sends out alarming signals according to a preset alarm condition; and the alarm alarms according to the alarming signals. In the negative pressure wound treatment system based on wound exudate managementof the invention, the arranged wound exudate management module can detect and display the physical parameters of the wound exudate and send out the alarming signals according to the preset alarm condition, and the alarm can alarm according to the alarming signals to promote medical workers to make follow-up treatment, therefore, the system provides greater convenience for the medical workers to manage and research the exudate and the work efficiency is improved.

The invention discloses a three-dimensional nanocomposite adhesive bandage as well as a preparation method and a use method thereof. The three-dimensional wound-protection layer of the adhesive bandage has a curved surface, and the curved surface is complementary to the uneven wound surface and comprises a nanobacterial cellulose frozen-dried membrane and an eletrospun chitosan-containing nanofiber film. The three-dimensional wound-protection layer can carry a part of liquid medicine. When in use, the adhesive bandage fully fits the wound surface, has air permeability, can keep the wound surface wet, has the functions of stop bleeding, inhibiting bacteria, promoting the healing of a wound and preventing the adhesion of the wound surface to the wound dressing and can be used widely. The adhesive bandage can well fit the concave wound surface and the convex wound surface, is applicable to the wet wound surface with many exudates, the dry wound surface which needs to be wetted by the wound dressing and the potential wound surface which needs protection, thereby being an ideal wound dressing.

The invention discloses a method for preparing a functional postoperative anti-adhesion material through 3D printing, relates to a method for preparing an anti-adhesion material, and aims to solve the problems that an existing postoperative anti-adhesion material is prone to suffer from cohesion failure, and application of the existing postoperative anti-adhesion material in complicated wounds is limited. The method comprises the following steps: preparing N, O-carboxymethyl chitosan, preparing aldehyde oxidized cellulose nanofibers, preparing dopamine modified oxidized cellulose nanofibers, dissolving the N, O-carboxymethyl chitosan, epsilon-polylysine and the dopamine modified oxidized cellulose nanofibers in deionized water and performing mixing to obtain printing ink, and performing 3D printing. The hydrogel disclosed by the invention has the characteristics of high wet adhesion, self-repairability, high strength, high toughness, softness, is prone to fit with skin and the like, and has the functions of resisting bacteria, stopping bleeding, controlling degradation, absorbing tissue exudate, keeping a wound surface moist and effectively promoting healing, and the usage amount can be accurately controlled by 3D printing to meet individual requirements of patients. The method is suitable for preparing the postoperative anti-adhesion material.

The invention discloses a medical sponge which comprises a chitosan application cushion layer, a water absorption layer and an anti-bacteria surface layer; the chitosan application cushion layer is composed of a chitosan film layer and gelatin microspheres composited into the chitosan film layer and loaded with fibroblast growth factors, and the anti-bacteria surface layer is a modified activatedcarbon fiber layer; the chitosan application cushion layer has the good histocompatibility and degradability, the fibroblast growth factors can be slowly released, and tissue growth and wound healingare promoted; the water absorption layer has the high absorptivity, percolate of a wound can be rapidly absorbed, and wound surface inflammations are reduced; the anti-bacteria surface layer can adsorb peculiar smell of medicine and the wound, the good anti-bacteria effect is achieved, the phenomenon that the wound is affected by bacteria in the external environment can be avoided, and wound healing is further protected. The medical sponge is convenient to use, medicine does not need to be replaced frequently, no stimulation or toxic or side effect is caused to skin, the wound can be protectedagainst infection, and the wound inflammations can be reduced.

The invention discloses a dressing prepared by using freeze-dried calcium alginate / vaterite calcium carbonate composite microspheres and a preparation method thereof. The dressing comprises compositemicrospheres loaded with a bacteriostatic drug and composite microspheres loaded with a cell growth factor, and the mass ratio of the composite microspheres loaded with the bacteriostatic drug to thecomposite microspheres loaded with the cell growth factor two is 1:1-5. The composite microsphere is prepared by uniformly mixing a uniformly dispersed vaterite calcium carbonate suspension and a sodium alginate solution and then using a microfluidic device. By using the calcium alginate / codbitite calcium carbonate composite microsphere as a release carrier, release period of the loaded drug and cell growth factor exceeds a week, thus avoiding frequent dressing change. In the early stage of wound healing by the use of the dressing, the freeze-dried calcium alginate layer blocks the bleeding site, the wound exudates is effectively absorbed, and the release of the bacteriostatic drug prevents bacteria breeding from infecting the wound. The growth factor is slowly and smoothly released duringthe whole period of wound recovery, thereby achieving the functions of stopping bleeding, inhibiting bacteria and promoting the repair and healing of wounded tissues.

The invention discloses a moist antibacterial hydrogel dressing for curing diabetic foot ulcer, and relates to the technical field of medical instruments and preparation thereof. The dressing is prepared by the following steps: dissolving ionic compounds in sodium alga acid water solution, and obtaining nano-silver sodium alga acid solution through adding reducing agent; adopting the impregnation method, placing the nano-silver sodium alga acid solution in a bacterial cellulose membrane, so as to obtain bacterial cellulose / nano-silver sodium alga acid composite membrane through freeze drying; and immersing the composite membrane in calcium chloride water solution, and obtaining the moist antibacterial hydrogel dressing for curing diabetic foot ulcer. The dressing is a composite hydrogel membrane including bacterial cellulose hydrogel and nano-silver contained calcium alginatehydrogel. The preparation is convenient to operate and low in cost, and the moist antibacterial hydrogel dressing prepared for curing diabetic foot ulcer has the performances of sterilizing, preserving moisture, absorbing wound percolate, quickening wound healing and the like, and is applied to curing wound traumas of diabetic foot ulcer, venous ulcer, pressure sores and donor site wounds at the lower limbs.

The invention relates to an oxygen-rich gel gent for promoting wound healing, a preparation method and applications thereof, wherein the oxygen-rich gel gent contains a Nereidae extracellular hemoglobin extraction solution, and the Nereidae extracellular hemoglobin extraction solution comprises the following components: Nereidae extracellular hemoglobin with a mass fraction of 0.1-10.0%, 5-20 mmol / L Ca<2+>, and 10-100 mmol / L Mg<2+>. According to the present invention, the gel agent prepared by using the Nereidae extracellular hemoglobin extraction solution has functions of sterilizing, moisture retention, wound exudate absorption and the like, and can promote the healing of refractory wounds, burn wounds, and contaminated wounds such as diabetic foot and bedsore wounds.

The invention discloses a negative pressure wound therapy (NPWT) system capable of detecting viscosity of wound exudates, comprising an exudates collecting bottle, an NPWT device, a wound kit and a device for detecting viscosity of wound exudates, wherein the exudates collecting bottle is used for collecting the wound exudates; the NPWT device comprises a negative pressure source and a controller; the wound kit is used for filling and sealing the wounds and is communicated with the exudates collecting bottle by a connecting pipe; and the device for detecting viscosity of wound exudates is used for detecting the viscosity of the wound exudates in the exudates collecting bottle. The system can detect the viscosity of the wound exudates, quantize the viscosity concretely, ensure the medical workers to more accurately know the viscosity of the wound exudates and timely treat the conditions such as higher viscosity and aggravated wounds, and provide convenience for the medical workers to study the wounds.

The invention relates to an article (1) to be applied against the skin, mucous membranes or a wound, in order to absorb a liquid, such as an exudate, said article comprising: a distal absorbent layer (20); one or more visual indicators (50) that change appearance upon contact with the liquid, said visual indicator(s) (50) being in contact with the distal absorbent layer (20); an interface (30) intended to come into contact with the skin or mucous membranes; at least one proximal absorbent layer (10) located adjacent to the interface (30) between the interface (30) and the distal absorbent layer (20); and at least one layer forming a water barrier (40) located between the proximal absorbent layer (10) and the distal absorbent layer (20) and provided with at least one passage (41) through which the liquid that has passed through the proximal absorbent layer (10) can reach the distal absorbent layer (20).

The invention belongs to the field of biological materials, and particularly relates to antibacterial hydrogel with photo-thermal performance and a preparation method and application thereof. A short-sequence antibacterial peptide (AMP) is connected with polypeptide hydrogel RADA16 through a glycine (G) joint, and the antibacterial hydrogel with inherent antibacterial activity is obtained. Then, a photo-thermal agent, namely copper sulfide nanodots (CuS NDs), is wrapped in the hydrogel, and is rapidly heated through irradiation of near-infrared light, so that a synergistic sterilization effect is generated with the antibacterial hydrogel. The antibacterial hydrogel has good biocompatibility, can continuously act on the surface of a wound, and can achieve the effects of ventilating, moisturizing and sucking out tissue exudate while effectively removing pathogenic bacteria, and meanwhile, the biodegradability of the antibacterial hydrogel further avoids secondary damage to new tissues during stripping. The antibacterial hydrogel is convenient to synthesize, high in safety, excellent in antibacterial performance and capable of effectively improving the healing quality of bacterial infected wounds.

The invention belongs to the field of medical instruments, particularly relates to the field of medical biopolymer materials, and provides a marine plant extract induced tissue repair hydrogel wound dressing and a preparation method thereof.The marine plant extract induced tissue repair hydrogel wound dressing is obtained by mixing and crosslinking polyvinyl alcohol, carbomer, undecylamide betaine, medical glycerol and growth factor-loaded alginate microspheres; wherein the growth factor loaded alginate microspheres are prepared by a spray drying method. The marine plant extract induced tissue repair hydrogel wound dressing disclosed by the invention not only has relatively strong imbibition and moisturizing performance and excellent film-forming performance, but also has excellent antibacterial performance, wound dirt removal performance and excellent continuous healing promotion performance; the hydrophilic growth factor-loaded alginate microspheres in the hydrogel wound dressing are swelled along with imbibition of alginate after being in contact with blood or exudate, and the growth factors contained in the alginate microspheres are slowly released, so that the aim of continuously promoting healing is fulfilled.

The invention discloses an electrospinning nanofiber membrane loaded with self-assembled traditional Chinese medicine component vesicles, and a preparation method and application thereof. Through the electrospinning technology, the water-soluble polymer material and the total glucosides of Centella asiatica are spun into the core layer, and the water-insoluble polymer material and the phospholipid are spun into the shell layer to form an electrospinning nanofiber membrane with a core-shell structure. In the early stage of trauma, the water-soluble material absorbs tissue exudate to expose the API, and the phospholipids encapsulate the free drug to form a vesicle structure to promote drug absorption, which ultimately promotes the formation of vascular endothelial cells and collagen fibers, and accelerates wound healing. The invention creatively applies research hotspots in the field of materials to a drug preparation delivery system, the prepared electrospinning nanofiber membrane is used for tissue regeneration and repair, and animal experiments achieve good results. The invention makes up for the defect that the existing trauma field relies on traditional treatment methods, provides a basis for the existing industrial production, and also provides a new choice for clinicians and patients to treat.

The invention relates to the technical field of traditional Chinese medicine compounds, and particularly relates to external cold compress gel for closed soft tissues. The external cold compress gel is prepared from borneol, frankincense, myrrh, radix angelicae dahuricae, dragon's blood and the like. Sodium alginate and collagen are used as carriers, the borneol, the frankincense, the myrrh, the radix angelicae dahuricae, the dragon's blood and some natural polymer substances are matched, and effective ingredients permeate subcutaneously by a transdermal absorption process to achieve a coolingeffect. The gel is applied to burn, scald, knife wound, frostbite, skin ulcer, nasal cavity, bedsore, postoperative parts and the like of a body in an in-vitro application mode, the effective ingredients go round along with meridians and collaterals and are used for wound surfaces to achieve the effects of stopping bleeding, diminishing inflammation, converging and repairing, wound surface inflammation and exudate adsorption drying are quickly achieved, healing and scabbing are repaired, the healing course is shortened, and the gel does not enter the digestive system in the body and has no harm or toxic or side effects. Cooling substances do not contain ingredients playing a pharmacological, immunological or metabolic role.

The invention discloses a medical dressing with antibacterial and high-absorption functions. The medical dressing comprises natural gauze, wherein antibacterial warp strips and antibacterial weft strips are arranged at the bottom end of the natural gauze and are mutually crossed and woven, a fiber layer is adhered to the lower parts of the antibacterial warp strips and the antibacterial weft strips, and a collagen layer is arranged at the bottom end of the fiber layer. The medical dressing has the advantages that the structure is scientific and reasonable, and the safety and convenience in useare realized; by arranging the natural gauze, wound exudate can be quickly absorbed; by mutually weaving the antibacterial warp strips and the antibacterial weft strips, the toughness of the dressingis further improved; by arranging the antibacterial warp strips and the antibacterial weft strips, the further antibacterial property of the medical dressing is guaranteed; by arranging the fiber layer, the sodium carboxymethyl cellulose fiber and the collagen layer are mutually matched, so that the skin tissue anabolism and cell regeneration are promoted, the local temperature and humidity of the skin are improved, and the blood circulation and metabolism of local skin cells are accelerated.

According to the embodiment, the invention provides a wound exudate weight detection method. The negative pressure wound therapy equipment comprises a liquid collection box and a weight detection device which is used for detecting weight information of wound exudates in the liquid collection box; and the wound exudate weight detection method comprises the following steps: measuring the weight of the empty liquid collection box by virtue of a mass sensor on the weight detection device; measuring the weight of the liquid collection box which is filled with the wound exudates of a patient by virtue of the mass sensor; and after therapy, acquiring the total weight of the wound exudates sucked by the negative pressure therapy equipment. According to the embodiment, the invention also correspondingly provides the negative pressure wound therapy equipment. According to the embodiment, by virtue of the wound exudate weight detection method as well as the negative pressure wound therapy equipment and a therapy system provided by the invention, precise measurement on the weight information of the wound exudates in the liquid collection box can be achieved, and manual weighing operation and recording can be avoided.

The invention relates to the field of research model and method for evaluation of an anti-bacterial property of a dressing, and in particular to an in-vitro model for measuring silver ion release of asilver-containing dressing. The in-vitro model includes a test cup and a culture tray; the test cup includes a raised portion and a sunken portion that are fixedly connected; a top surface of the raised portion is higher than a top surface of the sunken portion; a cavity is arranged in the test cup; an opening communicating with the cavity is formed on the top surface of the sunken portion; a liquid feeding port communicating with the cavity is formed on the raised portion; and a groove is formed on the culture tray. The invention further provides a method for measuring the silver ion releaseof the silver-containing dressing. According to the in-vitro model and the method provided by the invention, different types of wounds can be simulated; and through an in-vitro test of measuring silver ion release amount and release curve quantitatively at different time points after measuring a contact of a silver-containing dressing specimen with a percolate of a simulated wound, an effective component and an accumulative ion amount of the silver ion released in a dressing product are reflected scientifically and intuitively, and thus a release amount of the silver ion of the silver-containing dressing in a simulated clinical use state is evaluated dynamically.

The invention provides a chitosan-based multi-layer nanofiber membrane dressing. The dressing comprises a chitosan nanofiber membrane, a chitosan-hydrophilic polymer composite membrane and a hydrophilic polymer membrane which are sequentially stacked, wherein the hydrophilic polymer membrane is loaded with nano bioactive glass, and the chitosan-hydrophilic polymer composite membrane adopts a three-dimensional network structure formed by staggering chitosan nanofibers and hydrophilic polymer nanofibers. The chitosan-based multi-layer nanofiber membrane dressing comprises three layers, the chitosan nanofiber membrane on the bottom layer can stop bleeding and resist bacteria for wounds; the chitosan-hydrophilic polymer composite membrane on the middle layer can absorb tissue exudates and keep the wounds wet; the hydrophilic polymer membrane loaded with nano bioactive glass on the top layer gradually releases growth factors in the swelling process and promotes wound healing. The chitosan-based multi-layer nanofiber membrane dressing can respond to different stages of tissue healing to play different roles. The invention further provides a preparation method and an application of the chitosan-based multi-layer nanofiber membrane dressing.

The invention discloses a drainage device. The drainage device comprises a first draining part and a second draining part, wherein the first draining part is of a cylindrical structure; two ends of the first draining part is respectively provided with a first end face and a second end face; a draining slot is formed in the outer circumference of the first draining part, and is opened in the firstend face; and the second draining part has a hollow tubular structure with two opening ends, and runs through the first draining part in the direction from the first end face to the second end face. The drainage device has a good draining effect and can effectively shorten the recovery cycle after an operation. According to the drainage device, hematodes exudate around an anus wound is guided to enter the draining slot through the first draining part and is drained out; and the second end face is a closed end face, and faeces can only be drained out through the second draining part and cannotenter the draining slot, so that the exudate of the anus wound can be separated from the faeces in rectums due to the first draining part and the second draining part, and the infection probability ofanus wounds can be reduced.

A portable system for subatmospheric pressure therapy in connection with healing a surgical wound, including a wound dressing dimensioned for positioning relative to a wound bed of a subject and a subatmospheric pressure mechanism dimensioned to be carried or worn by the subject. The subatmospheric pressure mechanism includes a housing having a control unit adapted to draw a vacuum and a canister associated with the housing. The canister has a collection bag disposed therein, which is in fluid communication with the wound dressing to receive exudates from the wound bed. The collection bag is adapted to expand upon receipt of the fluids and has means to release gas from within the collection bag in connection with operation of the control unit. With this arrangement, the canister is attitude independent, i.e., the canister may be positioned on edge, on its side or on its end etc. while still maintaining operation of the control unit. The collection bag may include a hydrophobic vent or material for releasing the gases. In another embodiment, the collection bag comprises a gas permeable material. The collection bag may include one of pleats or bellows.

The invention relates to a cold compress infiltrating and sucking composition with the efficacy of clearing away internal heat and toxic materials, diminishing inflammation and relieving swelling forthe skin and a preparation method thereof. The cold compress infiltrating and sucking composition for the skin is prepared from, by weight, 10-15 parts of dried ginger, 10-15 parts of radix angelicaepubescentis, 10-15 parts of peach kernels, 10-15 parts of almonds, 10-15 parts of aloe, 10-15 parts of fructus hippophae, 10-15 parts of radix angelicae sinensis, 10-15 parts of rhizoma ligustici wallichii, 10-15 parts of pepper and 10-15 parts of radix glycyrrhizae. The composition has the effects of dilating blood vessels, promoting blood circulation, improving nutrition of surrounding tissue, increasing exudate, clearing away the internal heat and the toxic materials and relieving inflammation and swelling; the composition irritates and acts on the corresponding skin parts on the acupointsof the body surface, corrects the excessive abundance or excessive deficiency of yin and yang of the viscera and improves the circulation of qi and blood in the meridians and the collaterals through conduction and adjustment of the meridians and collaterals. In this way, a good treatment and adjustment effect is achieved on the physiological functions and pathological state of the viscera in orderto lead the functions of the viscera into balance, and the purpose of eliminating diseases is achieved.

The invention relates to gynecological gel, which is prepared from the following raw materials: aqueous gel and a traditional Chinese medicine extracting solution. The traditional Chinese medicine extracting solution is a mixed traditional Chinese medicine extracting solution which is prepared by mixing the following raw materials: fructus cnidii, radix sophorae flavescentis, radix saposhnikoviae, menthol, coptis chinensis, cynanchum atratum, pseudo-ginseng, dragon's blood, selfheal, honeysuckle, dandelion, fructus kochiae, borneol and water. Compared with the prior art, the gynecological gel has the advantages that the adopted aqueous gel can absorb tissue exudate, does not hinder the normal function of the skin, and has characteristics of small thickness, drug release benefiting, easy spreading, easy washing, no greasy feeling and the like; the gynecological gel is prepared by using the traditional Chinese medicines as the main raw materials and cooperating with the aqueous gel, has characteristics of no stimulation, significant treatment effect, small side effect, significant anti-inflammation, sterilization, pain relieving and itching relieving effects; the growth of pathogenic bacteria such as staphylococcus aureus, escherichia coli, gonococcus, candida albicans, fungi, saccharomycetes and the like can be obviously inhibited.