29 results about "Exudate/transudate" patented technology

The invention discloses an antibacterial dressing based on gallic acid-copper coated gamma-polyglutamic acid and a preparation method and application thereof, and belongs to the technical field of biomedicines.The preparation method comprises the steps that gallic acid and copper chloride dihydrate are dissolved in pure water according to the mass ratio of 3: 1, and stirring is conducted to form a solution I; stirring and reacting the solution I at 40 DEG C for 24 hours, centrifuging, collecting precipitate, washing with pure water, and freeze-drying to obtain gallic acid-copper nanoparticles; the gallic acid-copper nanoparticles and gamma-polyglutamic acid powder are mixed and dissolved in pure water according to the mass ratio of 3: 20, and after freeze drying, gallic acid-copper coated gamma-polyglutamic acid hydrogel powder is obtained. The gallic acid-copper coated gamma-polyglutamic acid hydrogel powder disclosed by the invention can absorb exudate near a wound and is subjected to in-situ gelation to form a hydration layer, so that damage to newborn tissues caused by frequent dressing replacement is avoided; it is verified that the healing promoting effect of the hydrogel can be remarkably enhanced through blue light adjuvant therapy, and the healing speed of infected wounds is remarkably increased.

The utility model discloses a drainage tube orifice seepage ostomy bag capable of preventing a catheter from slipping, and aims to provide the drainage tube orifice seepage ostomy bag capable of preventing the catheter from slipping, which can be matched with the catheter to collect seepage at a wound. The ostomy bag comprises an ostomy bag body, an adsorption disc and a piston switch, a receiving hole is formed in the rear end face of the ostomy bag body, the adsorption disc is installed on the ostomy bag body and corresponds to the receiving hole, a penetrating hole is formed in the front end face of the ostomy bag body, and the piston switch is installed at the lower end of the ostomy bag body. The utility model has the beneficial effects that the device can be matched with a catheter to collect the exudate at the wound, is convenient to release the exudate, can better correspond to the wound, can reduce the sliding of the catheter, can ensure that the catheter is fixed more firmly, and is convenient to observe the collection amount of the exudate.

The present application relates to the technical field of wound repair material, in particular to a chronic wound dressing and a preparation method thereof, the wound dressing is prepared from a first contact layer, an intermediate transition layer and a backing layer which are in direct contact with the wound, through the unique three-layer structure design, a chronic wound dressing with fast healing speed, strong anti-inflammatory and antibacterial properties, high liquid absorption and effective regulation of the microenvironment of the wound is prepared, the first contact layer is in direct contact with the wound, absorbs the exudate, plays an anti-inflammatory and antioxidant role, the intermediate transition layer guides the exudate from the first contact layer to the backing layer through the asymmetric fiber membrane structure on both sides and does not back permeate, the backing layer has a connected microporous structure, has strong air permeability and can absorb a large amount of exudate, provides a humid environment for the wound, inhibits bacterial growth and promotes wound healing, compared with the prior art, has a wide application prospect.

The present invention discloses an anti-inflammatory and healing-promoting electrospun wound dressing, a preparation method and an application thereof, belonging to the technical field of medical dressings, and comprising a double-layer structure of an inner layer and an outer layer; wherein, the outer layer is a hydrophilic nanofiber membrane prepared by single-nozzle electrospinning, and is used to absorb wound exudate; the inner layer is a nanofiber membrane with a core-shell structure prepared by coaxial electrospinning, and the shell layer of the core-shell structure is a hydrophobic material, and is used to guide the exudate to the outer layer; the core layer of the core-shell structure comprises hydrophilic thermosensitive macromolecules, healing-promoting growth factors and anti-inflammatory drugs; the shell layer is hydrophobic, and guides the wound exudate to the outer hydrophilic nanofiber membrane; the gelatin hydrophilic thermosensitive macromolecules in the core layer, when the wound inflammation causes the local temperature to be ≥37°C, the temperature change causes the drug-loaded thermosensitive phase change macromolecules to undergo different degrees of phase change, thereby achieving timely and controllable release of drugs and ensuring the healing of the wound surface.

The invention relates to a degradable manganous-manganic oxide-tannic acid-polymer composite modified artificial dura mater and preparation thereof, and belongs to the technical field of biological materials. According to the modified artificial dura mater, a spongy collagen biological membrane scaffold beneficial to cell growth and new dura mater tissue generation is provided for a dura mater defect part, and the modified artificial dura mater with good tissue compatibility and degradability is prepared by introducing carboxymethyl chitosan and manganous-manganic oxide / tannic acid. The novel composite artificial dura mater can effectively reduce intracranial infection and leakage of cerebrospinal fluid. The modified artificial dura mater loaded with the antioxidant manganous-manganic oxide / tannic acid nano-composite can effectively remove free radicals in the brain, and the composite modified artificial dura mater has anti-inflammatory and antibacterial functions and can be adhered to the surface of the dura mater after absorbing tissue exudate, water, buffer solution and the like. And can be tightly attached to the dura mater without suturing, and can exert antibacterial and anti-inflammatory activity for a long time.

The application discloses a self-gel powder with functions of rapid hemostasis and lossless removal, a preparation method and application thereof, and belongs to the technical field of biomedical materials. The self-gel powder is prepared from acrylic acid, 3-sulfonic acid propyl methyl acrylic acid potassium salt, quaternary ammonium salt chitosan, tannic acid, calcium ions and methanesulfonic acid deferoxamine through copolymerization, freeze-drying and grinding. The preparation process is simple, and the material has excellent biocompatibility. The powder can be rapidly self-gelated within 30 seconds after contacting with blood or exudate of a wound, and rapid hemostasis is achieved through the cooperation of positive and negative charge adsorption, calcium ion coagulation promotion and physical barrier plugging. Meanwhile, the powder has multiple biological activities such as broad-spectrum antibacterial activity, anti-inflammatory activity and antioxidant activity. After hemostasis is completed, the powder can be gently washed with normal saline to realize lossless removal, thereby avoiding secondary damage. Animal experiments show that the material can effectively promote the healing of a diabetic wound, and provides an integrated and whole-cycle repair scheme for a chronic and difficult-to-heal wound.

The invention discloses a double-cavity anti-leakage drainage tube which comprises an annular self-adhesion base plate and an eccentric funnel connecting plate arranged below a middle through hole of the annular self-adhesion base plate, a near-end double-cavity drainage tube is connected below a ventage of the eccentric funnel connecting plate, a detachable drainage tube is arranged in a first cavity of the near-end double-cavity drainage tube, and a second cavity of the near-end double-cavity drainage tube is connected with a second cavity of the annular self-adhesion base plate. A plurality of side holes are formed in the side wall of the top of the detachable drainage tube, the bottom of the double-cavity drainage tube is connected with a far-end single-cavity drainage tube, a drainage tube clamp is arranged on the far-end single-cavity drainage tube, and the tail end of the far-end single-cavity drainage tube is connected with a negative-pressure or normal-pressure drainage bag. By means of the near-end double-cavity drainage tube, it is avoided that exudate is excessively accumulated in the eccentric funnel connecting disc when a user sideways, the liquid exudating around a wound flowing down from the outer wall of the detachable drainage tube is collected through the second cavity, pollution to clothes and bedding and wound tissue infection caused by exudation around the drainage tube can be effectively reduced, wound healing is promoted, and the wound healing rate is increased. And the times of dressing change and the pain of patients are reduced.

A cleaning system is provided for cleaning a patient's wounds and / or body cavities, particularly the pericardial cavity (PC) and / or pleural cavity. [Solution] The cleaning system includes a carrier unit configured to be movable, an inflow unit including at least one infusion fluid container for containing an infusion fluid, and a collection unit configured to collect exudate from a patient, wherein the carrier unit is configured to house the inflow unit and the collection unit, the inflow unit further includes at least one first weighing unit for measuring the weight of the infusion fluid delivered to the patient, and the carrier unit includes a second weighing unit for measuring the weight of the exudate collected in the collection device.

1. Name of the product in this design: Leak-proof bag. 2. Purpose of this design: A drainage bag to prevent leakage when draining body fluids or tissue exudate from postoperative patients. 3. The key design feature of this product is the shape of the leak-proof bag. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The application discloses a preparation method of a composite hydrogel dressing, and is characterized by comprising the following step A1. raw material preparation: 20-40 parts of Astragalus membranaceus, 10-20 parts of Atractylodes macrocephala, 10-20 parts of Angelica sinensis, 5-15 parts of Carthamus tinctorius, 3-10 parts of dragon's blood, and 5-15 parts of Bai Zhi. The prepared composite hydrogel dressing has the characteristics of softness and hydrophilicity, can be closely attached to a wound surface of various shapes, and can well cover a flat wound surface or an irregular wound surface, so that a moist healing environment is provided for the wound surface. The moist environment is favorable for the proliferation and migration of wound cells, promotes wound healing, and can also reduce pain during dressing change. The dried hydrogel can form a porous sponge structure, the structure has strong water absorption, can quickly absorb exudates of the wound surface, keeps the wound surface dry, prevents infection caused by accumulation of the exudates, and is convenient for management of the exudates.

A flushing system comprises: an infusion liquid outlet to connect to a first tube arrangement having a plurality of infusion liquid lumen guiding a flow of infusion liquid from the system to a wound and / or body cavity; an effusion liquid inlet to connect to a second tube having an effusion liquid lumen guiding the effusion liquid from the wound and / or the body cavity to the system; and a flow rate control system to control the flow rate at the infusion liquid outlet. The flow rate control system comprises: a control unit, and a pump device to pump infusion liquid to the infusion liquid outlet at a flow rate adjustable by control signals of the control unit. Each infusion liquid lumen of the first tube arrangement has openings arranged along the first tube arrangement and spaced from one another for leading the infusion liquid into the wound and / or the body cavity.

A biosensor for detecting a biomarker in body fluids, secretions, or exudates is described. The biosensor essentially comprises a first electrode (100a), a second electrode (100b), an electrode coating (200), and a mechanical electrode stabilizer (300). The biomarker is an enzyme that catalyzes a chemical reaction in which one or more components of the electrode coating (200) are chemically altered by the breaking of covalent bonds upon contact with it. The electrode coating comprises a natural or synthetic substrate of the biomarker. The first and second electrodes are electrically conductive and are maintained at a virtually constant and uniform distance from each other by the mechanical electrode stabilizer (300). The exposed conductive surface of at least one of the electrodes is almost completely covered by the electrode coating (200).The biosensor exists in at least one state from the group of states comprising a high-impedance state, in which the electrode coating (200) remains virtually unchanged by the biomarker, and a low-impedance state, in which the electrode coating (200) is chemically altered by the biomarker. A wound diagnostic dressing system incorporating the biosensor of the invention is also provided.

In some embodiments, a negative pressure wound therapy system can detect and classify one or more operational conditions, including detection of a wound bleeding. The system can react to detection of blood by providing an indication, reducing the intensity or stopping therapy, releasing negative pressure, etc. In certain embodiments, the system can detect one or more additional operational conditions, such as change in vacuum pressure, gas leak rate change, exudate flow rate change, water flow rate change, presence of exudate, presence of water, etc. The system can detect and distinguish between different operational conditions and provide indication or take remedial action.

The invention belongs to the technical field of medical instruments, and particularly relates to an anorectal postoperative analgesia and hemostasis device which comprises a base plate, an outer tube is mounted on the base plate, an inner tube is mounted on the inner side of the outer tube, an administration assembly is mounted in the outer tube, a wriggling assembly is mounted in the inner tube, and a transmission assembly is mounted at the bottom of the base plate. The wriggling assembly comprises an elastic inner film, an air exhaust sleeve and a transmission sleeve. When medicine needs to be applied to an affected part, the double-end sliding plate moves towards the liquid supply cavity, the first push plate moves away from the second piston, the second push plate moves close to the second piston, and due to the fact that the double-end sliding plate is in sliding fit with the second piston, the second piston does not move. In the process that the double-end sliding plate moves towards the liquid supply cavity, the double-end sliding plate drives the first piston to move towards the liquid supply cavity, negative pressure is generated in the liquid suction cavity, interstitial fluid and blood exuding from the affected part are sucked into the liquid suction cavity, exudates of the affected part are cleared away in time, and the infection risk of the affected part is reduced.

This invention discloses a negative pressure suction device for purulent secretions and inflammatory exudates, relating to the field of medical device technology. Through the combination of a bifurcated connector and a one-way valve, this invention can accurately deliver irrigation fluid to dilute purulent secretions and inflammatory exudates, while also promptly removing the mixed liquid to prevent secretions from remaining on the wound surface. This achieves simultaneous and coordinated irrigation and suction. Furthermore, the one-way valve effectively blocks backflow, preventing contamination of the irrigation fluid source and ensuring the aseptic nature of the irrigation process. The inclined design of the emergency flushing tube quickly clears blockages, ensuring continuous and smooth negative pressure suction. The suction head reduces scratching or irritation to fragile tissues around the wound, and the combination of breathable dressing and fixing wings prevents suction head displacement, reducing the risk of wound bleeding or secondary injury, and improving patient comfort and treatment safety. The standardized interface and interference fit connection facilitate quick installation and disassembly by medical personnel, saving operation time.

The present invention discloses a drainage device. The drainage device includes a first drainage component and a second drainage component. The first drainage component is a columnar structure. The two ends of the first drainage component respectively have a first end face and a second end face. The outer peripheral surface of the first drainage component has a drainage groove, and the drainage groove is also open to the first end face; the second drainage component is a hollow tubular structure with two ends open. The second drainage component is arranged in the direction from the first end face to the second end face through the first drainage component. The drainage device has a good drainage effect and can effectively shorten the postoperative recovery period. The drainage device of the present invention can guide the bloody exudate around the anal wound into the drainage groove and discharge it through the first drainage component; because the second end face is a closed end face, feces can only be discharged through the second drainage component and will not enter the drainage groove. The first drainage component and the second drainage component realize the separation of the anal wound exudate and the feces in the rectum to reduce the chance of anal wound infection.

The utility model discloses a drainage plug for an extraction operation of embedded impacted teeth, which comprises a main body structure and a drainage plug, the side wall of the main body structure is provided with at least one fixing unit used for anchoring the main body structure to the peripheral tissue of the alveolar fossa; one end of the main body structure is provided with an expandable limiting component which is matched with the inner wall of the alveolar fossa to prevent the main body structure from falling off; the main body structure is composed of multiple layers of degradable materials and comprises an outer functional layer and an inner supporting layer. Continuous exudate diversion is achieved through the drainage channel in the main body structure, effusion in a closed environment is reduced, so that the swelling and infection probability is reduced, through the double retention design of the side wall fixing unit and the expandable limiting component, the fitting performance of the drainage plug and an alveolar fossa is enhanced, intraoperative and postoperative disengagement is prevented, and the drainage effect is improved. The multi-layer degradable material is adopted, the outer functional layer rapidly degrades and drains, and the inner supporting layer slowly degrades and supports, so that the device does not need to be taken out, and new tissues are prevented from being torn.

The application discloses a kind of sodium hyaluronate-polyurethane composite hemostatic anti-adhesion sponges for uterine cavity and its preparation method and application, it is related to medical biological composite material technical field;The composite hemostatic anti-adhesion sponge includes sodium hyaluronate crosslinking gel and polyurethane and its porosity is 70%~95%, water absorption is 8~20 times of its own mass, tensile strength is 0.4~1.2MPa, in vitro degradation period is 20~45 days, crosslinking agent residual amount is less than 0.1ug / g, cytotoxicity is less than or equal to 1 level;Sodium hyaluronate crosslinking gel will form soft and lubricious physical barrier after water absorption and expansion, effectively isolate uterine anterior and posterior wall wound, prevent adhesion, provide environment for wound healing;Polyurethane sponge can quickly reach relatively balanced water absorption, help to quickly absorb uterine cavity exudate, keep wound clean, also can provide mechanical support, prevent uterine cavity contracture deformation;Polyurethane is matched with uterine cavity clinical healing period, and degradation product has no toxicity residue.

The invention discloses an aspirator with a replaceable head, which comprises a main body provided with an aspiration channel, a detachable adsorption part, a connecting structure and an operating handle, the adsorption part is made of a flexible porous material, rapid replacement is realized through a mortise and tenon structure, and the design has dual functions of tissue traction and blood adsorption; exudate in an operation area can be effectively absorbed while enough operation friction force is kept, the head can be replaced immediately when blocked in the operation due to the modular structural design, the operation efficiency is improved, and the novel surgical instrument is particularly suitable for the fine operation field of neurosurgery, plastic surgery and the like.

Apparatus, systems, and methods for purging exudate from a fluid container suitable for use with negative pressure therapy. A canister assembly configured to purge exudate can include a primary container, a first one-way valve, and a second one-way valve. The primary container can include an internal volume, a pressure inlet port, an exudate inlet port, and an exudate outlet port each in fluid communication with the internal volume. The first one-way valve can be in fluid communication with the exudate inlet port and the internal volume and configured to permit fluid flow into the internal volume and to restrict fluid flow out of the internal volume. The second one-way valve can be in fluid communication with the exudate outlet port and the internal volume and configured to permit fluid flow out of the internal volume and to restrict fluid flow into the internal volume.

A dressing for negative pressure wound therapy (NPWT) of a wound is provided. The dressing includes a dressing. The dressing includes a manifold adapted to be positioned adjacent to the wound for receiving negative pressure. The dressing further includes a base foam disposed on the manifold. The dressing further includes an accumulation chamber defined in the base foam and configured to be disposed in fluid communication with an outlet of a negative pressure source. The dressing further includes a top foam disposed on the base foam. The dressing further includes a pre-canister defined in the top foam and configured to be disposed in fluid communication with the manifold and the accumulation chamber. The pre-canister is configured to receive pressurized air from the accumulation chamber when the negative pressure source is in an off state, thereby purging the pre-canister by allowing exudate flow from the pre-canister to a final canister.

In some embodiments, a negative pressure wound therapy system can detect and classify one or more operational conditions, including detection of a wound bleeding. The system can react to detection of blood by providing an indication, reducing the intensity or stopping therapy, releasing negative pressure, etc. In certain embodiments, the system can detect one or more additional operational conditions, such as change in vacuum pressure, gas leak rate change, exudate flow rate change, water flow rate change, presence of exudate, presence of water, etc. The system can detect and distinguish between different operational conditions and provide indication or take remedial action.

1. The name of the design product: portable negative pressure drainage instrument. 2. The use of the design product: for using negative pressure to suck out the liquid such as exudate, pus, blood and the like from the wound, body cavity and the like. 3. The design points of the design product: in shape. 4. The picture or photo best indicating the design points: perspective view.

A method for measuring the conformability of a dressing (D) to a wound bed comprising: - a step of preparing a physical model (16) which simulates the irregular surface of a skin lesion, for example a skin ulcer, wherein the model defines a cavity (17), - a step of filling the cavity (17) with a liquid (L) which simulates the presence of exudate, - a step of positioning the dressing (D) on the model (16) so that the dressing (D) covers the cavity (17), - a step of detecting and processing images of the model (16) to determine a numerical value representative of the conformability.

The invention discloses an efficient antibacterial composition containing marine oligosaccharide and application of the efficient antibacterial composition, and belongs to the technical field of biology. According to the antibacterial composition, the synergistic effect of the natural lysozyme and the polyguluronic acid is fully utilized, the antibacterial activity of the composition is improved, and especially the inhibiting effect on gram-negative bacteria is improved. The composition forms a gel matrix under a low pH condition, lysozyme can be well protected, when the pH is increased, the composition dissolves and releases the lysozyme, in addition, polyguluronic acid can competitively combine with a microbial extracellular biological membrane to form necessary calcium ions, so that the formation of the microbial extracellular biological membrane is hindered, the drug resistance of bacteria is reduced, and the lysozyme can be effectively protected. The composition disclosed by the invention can treat various pathogenic bacteria such as gram-positive bacteria, gram-negative bacteria and fungi which cause skin trauma, and meanwhile, the composition can be crosslinked with calcium ions of tissue exudate to form a gel barrier to promote wound healing.

The invention relates to the technical field of medical dressings, and discloses a biological amniotic membrane dressing and a preparation method thereof. The biological amniotic membrane dressing is composed of an alginate non-woven fabric bottom layer, a polyacrylamide temperature-sensitive gel amniotic membrane copolymerization middle layer and an amniotic membrane surface layer. Acrylic acid grafting is initiated through ceric ammonium nitrate, the hydrophilicity of the alginate non-woven fabric is combined with the ion exchange capacity, a bottom layer supporting and exudate management system is constructed, exudate can be absorbed and discharged in time in the repairing process, and therefore the phenomenon of effusion is avoided. The biological amniotic membrane dressing prepared from amniotic membrane sol obtained by enzymolysis of amniotic membrane has a better effect of promoting wound healing, is tightly attached to a wound, reduces infection and is suitable for covering acute and chronic wound surfaces.

The present application relates to the technical field of medical dressings, and discloses a biological amniotic membrane dressing and a preparation method thereof. The biological amniotic membrane dressing is composed of an alginate non-woven fabric bottom layer, a polyacrylamide temperature-sensitive gel amniotic membrane copolymerization intermediate layer and an amniotic membrane surface layer. The biological amniotic membrane dressing is helpful for the adhesion and slow release of drugs and wounds, and the hydrophilicity and ion exchange capacity of the alginate non-woven fabric are combined by grafting acrylic acid initiated by cerium ammonium nitrate to construct a bottom layer support and exudate management system, which is beneficial to timely absorption of exudate and discharge in the repair process, thereby avoiding the phenomenon of fluid accumulation. The biological amniotic membrane dressing prepared by subjecting the amniotic membrane to enzymolysis to obtain an amniotic membrane sol has a better effect of promoting wound healing, closely fits the wound, reduces infection, and is suitable for covering acute and chronic wounds.

This invention relates to the field of dressings, specifically to a medical wound dressing. The medical wound dressing includes a membrane dressing comprising an outer surface layer and an intermediate layer. The outer surface layer is an overlaid matrix layer, and the intermediate layer includes at least a lyophilized matrix layer. The overlaid matrix layer and the lyophilized matrix layer are decellularized matrix materials of the same species and from the same tissue. The medical wound dressing obtained by this method has excellent tear resistance and handling feel, is not easily curled, deformed, or delaminated, and can be designed as either non-porous or perforated. It can be used for both dry / low-exudate wounds and highly fluidized wounds that produce large amounts of exudate. The non-porous membrane dressing is used for dry / low-exudate wounds, while the perforated membrane dressing is used for highly fluidized wounds that produce large amounts of exudate.

The utility model discloses an aspirator with a replaceable head, which comprises a main body provided with an aspiration channel, a detachable adsorption part, a connecting structure and an operating handle, the adsorption part is made of flexible porous materials and can be quickly replaced through a mortise and tenon structure, and the design has dual functions of tissue traction and blood adsorption. Exudate in an operation area can be effectively absorbed while enough operation friction force is kept, the head can be replaced immediately when blocked in the operation due to the modular structural design, the operation efficiency is improved, and the novel surgical instrument is particularly suitable for the fine operation field of neurosurgery, plastic surgery and the like.