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Burn dressing applicable to department of burn and having antibacterial effect

A technology of fruit acid and sodium ascorbyl phosphate, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of not being able to inhibit bacteria, wound infection, skin irritation, etc., so as to improve the recovery effect, promote absorption, and accelerate Recovery effect

Inactive Publication Date: 2016-09-07
李明华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] But above-mentioned dressing still has certain stimulation to skin, and can not suppress bacterium preferably, causes wound infection easily

Method used

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  • Burn dressing applicable to department of burn and having antibacterial effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Step 1, in parts by weight, add 15 parts of glycerin to 3 parts of alginate, 4 parts of glycolic acid, 10 parts of vitamin E, 2 parts of sodium ascorbyl phosphate, and 3 parts of sodium polyacrylate, and stir evenly to obtain a mixed solution ;

[0024] Step 2, in parts by weight, take 30 parts of purslane, 30 parts of astragalus, and 20 parts of honeysuckle, mix them, add 200 parts of water, extract at 40°C for 0.5 hours, and filter to obtain the extract;

[0025] The 3rd step, by weight, after pulverizing 1 part of bamboo fiber, mix with 5 parts of 1.0mol / L hydrochloric acid solution, heat and carry out hydrolysis reaction, after reaction finishes, filter out residue, residue is washed with water to pH neutrality, Then the residue, 0.2 parts of polyethylene glycol, and 5 parts of water were mixed evenly, and the temperature was raised to 80°C for reaction to obtain a white slurry, which was spray-dried to obtain modified microcrystalline cellulose;

[0026] Step 4, b...

Embodiment 2

[0029] Step 1, in parts by weight, add 30 parts of glycerin to 5 parts of alginate, 6 parts of glycolic acid, 15 parts of vitamin E, 4 parts of sodium ascorbyl phosphate, and 5 parts of sodium polyacrylate, and stir evenly to obtain a mixed solution ;

[0030] Step 2, in parts by weight, take 50 parts of purslane, 60 parts of astragalus, and 30 parts of honeysuckle, mix them, add 400 parts of water, extract at 60° C. for 1 hour, and filter to obtain the extract;

[0031] The 3rd step, by weight, after pulverizing 2 parts of bamboo fiber, mix with 20 parts of 1.0mol / L hydrochloric acid solution, heat and carry out hydrolysis reaction, after reaction finishes, filter out residue, residue is washed with water to pH neutrality, Then, mix the residue, 0.4 parts of polyethylene glycol, and 8 parts of water evenly, and heat up to 90°C to react to obtain a white slurry, which is spray-dried to obtain modified microcrystalline cellulose;

[0032] Step 4, in parts by weight, dissolve 6...

Embodiment 3

[0035] Step 1, in parts by weight, add 20 parts of glycerin to 4 parts of alginate, 5 parts of glycolic acid, 12 parts of vitamin E, 3 parts of sodium ascorbyl phosphate, and 4 parts of sodium polyacrylate, and stir evenly to obtain a mixed solution ;

[0036] Step 2, in parts by weight, take 40 parts of purslane, 50 parts of astragalus, and 25 parts of honeysuckle, mix them, add 300 parts of water, extract at 50°C for 0.8 hours, and filter to obtain the extract;

[0037] The 3rd step, by weight, after pulverizing 2 parts of bamboo fiber, mix with 12 parts of 1.0mol / L hydrochloric acid solution, heat and carry out hydrolysis reaction, after reaction finishes, filter out residue, wash residue with water to pH neutrality, Then, mix the residue, 0.3 parts of polyethylene glycol, and 7 parts of water evenly, and heat up to 85°C to react to obtain a white slurry, which is spray-dried to obtain modified microcrystalline cellulose;

[0038] Step 4, in parts by weight, dissolve 5 par...

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Abstract

The invention relates to a burn dressing applicable to department of burn and having an antibacterial effect, and belongs to the technical field of medical dressings. The burn dressing is mainly prepared by the following steps: preparing a mixed solution which consists of algin acid, vitamin E, sodium ascorbyl phosphate, sodium polyacrylate and glycerol; preparing extracting solutions of herba portulacae, radix astragali and honeysuckle flower; and conducting a cross-linking reaction by virtue of a water-soluble polymer, starch, modified microcrystalline cellulose, water, an antibacterial agent and a cross-linking agent, so that the dressing is prepared. According to the burn dressing disclosed by the invention, the radix astragali has functions of replenishing qi to strengthen superficial body resistance, inducing diuresis and draining toxins, expelling pus, healing sores and promoting generation of fresh tissue. Astragaloside, as a main active ingredient in the radix astragali, has a certain effect on promoting healing of traumatic wounds; the herba portulacae is effective on promoting wound recovery and enhancing the antibacterial effect; the algin acid is capable of promoting absorption of medicines and improving a recovery effect; and the burn dressing, in the dosage form of a hydrogel, has a good effect on the recovery of burns.

Description

technical field [0001] The invention relates to a burn dressing with antibacterial effect used in a burn department, and belongs to the technical field of medical dressings. Background technique [0002] Burns are injuries caused by factors such as flames, hot water, hot steam, hot oil, hot cement, electric current, chemical substances and radioactive substances acting on human skin, mucous membranes, muscles, etc. The series of local and systemic reactions and the clinical course that occur after thermal skin injury depend on the size, location, and depth of the burn in the patient. [0003] The pathophysiology and clinical stages of burns can be divided into: 1. Acute body fluid exudation stage (shock stage): the immediate reaction after tissue burn is body fluid exudation, and the main threat to the patient's life within 48 hours after injury is shock. 2. Infection period: Once the recovery period of burn edema begins, infection will become the main contradiction. Bur...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/42A61L15/44A61L15/46A61L15/40A61L15/20
CPCA61L15/42A61L15/20A61L15/40A61L15/44A61L15/46A61L2300/30A61L2300/412
Inventor 李明华刘进辉
Owner 李明华
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