Bionic gynecological lotion and preparing method thereof
A gynecological lotion and biomimetic technology, which can be used in pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc., can solve the problems of short residence time, poor vaginal compatibility, and reduced biological activity of antimicrobial peptides. and other problems, to achieve the effect of vaginal acidity repair, simple preparation method and balance of vaginal flora
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Embodiment 1
[0031] Embodiment 1, a kind of bionic gynecological lotion
[0032] The present embodiment 1 bionic gynecological lotion is composed of the following components: housefly antimicrobial peptide 0.1g, xylooligosaccharide 6.0g, xanthan gum 0.1g, NaCl 8.0g, KCl 0.45g, CaCl 2 0.15g, NaHCO 3 0.4g, MgCl 2 ·6H 2 O 0.015g, MgSO 4 ·7H 2 O 0.05g, KH 2 PO 4 0.06g, Na 2 PHO 4 12H 2 0.06g, glucose 1.0g, urea 1.5g, Gram-positive bacterial cell fragments 0.002g, be settled to 1L with deionized water, wherein, described growth factor is made of recombinant human epidermal growth factor and recombinant human basic fibroblast The cell growth factor is composed at a weight ratio of 1:1, and the Gram-positive bacterial cell fragments are composed of bifidobacterium cell fragments and lactobacillus cell fragments at a weight ratio of 1:1.
[0033] Preparation:
[0034] A) NaCl, KCl, CaCl 2 , NaHCO 3 , MgCl 2 ·6H 2 O, MgSO 4 ·7H 2 O. KH 2 PO 4 、Na 2 PHO 4 12H 2 O, urea, Gram...
Embodiment 2
[0037] Embodiment 2, a kind of bionic gynecological lotion
[0038] The bionic gynecological lotion of Example 2 is composed of the following components: 0.1 g of housefly antimicrobial peptide, 6.0 g of xylooligosaccharide, 0.1 g of xanthan gum, 8.0 g of NaCl, 0.45 g of KCl, and 0.45 g of CaCl 2 0.15g, NaHCO 3 0.4g, MgCl 2 ·6H 2 O 0.015g, MgSO 4 ·7H 2 O 0.05g, KH 2 PO 4 0.06g, Na 2 PHO 4 12H 2 O0.06g, glucose 1.0g, urea 1.5g, Gram-positive bacterial cell fragments 0.002g, water-soluble VE0.4g, natural moisturizing factor 0.2g and free amino acid 0.4g, be fixed to 1L with deionized water, wherein, The growth factor is composed of recombinant human epidermal growth factor and recombinant human basic fibroblast growth factor in a weight ratio of 1:1, and the free amino acid is composed of glycine, alanine, aspartic acid and serine in a 1:1 ratio. : 1:1 weight ratio, the Gram-positive bacterial cell fragments are composed of bifidobacterium cell fragments and lactoba...
Embodiment 3
[0040] Embodiment 3, a kind of bionic gynecological lotion
[0041] The bionic gynecological lotion of Example 3 is composed of the following components: 0.2 g of housefly antimicrobial peptide, 5.0 g of xylooligosaccharide, 0.1 g of xanthan gum, 8.0 g of NaCl, 0.45 g of KCl, and 0.45 g of CaCl 2 0.15g, NaHCO 3 0.4g, MgCl 2 ·6H 2 O 0.015g, MgSO 4 ·7H 2 O 0.05g, KH 2 PO 4 0.06g, Na 2 PHO 4 12H 2 O0.06g, glucose 1.0g, urea 1.5g, Gram-positive bacterial cell fragments 0.001g, water-soluble VE 0.4g, natural moisturizing factor 0.2g and free amino acid 0.4g, use deionized water to make up to 1L, wherein, The growth factor is composed of recombinant human epidermal growth factor and recombinant human basic fibroblast growth factor in a weight ratio of 1:1, and the free amino acid is composed of glycine, alanine, aspartic acid and serine in a 1:1 ratio. : 1:1 weight ratio, the Gram-positive bacterial cell fragments are composed of bifidobacterium cell fragments and lacto...
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