Chinese herbal medicine compound preparation for preventing and treating chthyophthirius multifilis for fish as well as preparation and application of Chinese herbal medicine compound preparation

Abstract

The invention discloses a Chinese herbal medicine compound preparation for preventing and treating chthyophthirius multifilis for fish as well as preparation and application of the Chinese herbal medicine compound preparation, and belongs to the technical field of fish parasite killing medicines. The compound preparation is prepared from the following raw material medicines by weight percentage: 20-40% of radix sophorae flavescentis and 60-80% of radix cynanchi atrati, wherein a preparation method of the compound preparation comprises the following steps: respectively drying and crushing the raw material medicines; screening to obtain dry powder of each raw material medicine; mixing the obtained dry powder of the raw material medicines by weight percentage; adding 95% of ethanol; soaking and extracting for twice to obtain a total extract; decompressing and concentrating the obtained total extract; and drying the obtained extract until the weight is constant, to obtain the Chinese herbal medicine compound preparation for preventing and treating chthyophthirius multifilis for fish. The Chinese herbal medicine compound preparation provided by the invention is easy to decompose, free of residues and safe to environment and people, reduces toxicity of a coarse extract of radix cynanchi atrati, improves efficacy of radix sophorae flavescentis to resist ichthyophthiriasis, greatly reduces cost, is easy to industrial production and promotion, and has broad application prospects in aquatic product.

Description

technical field [0001] The invention belongs to the technical field of drugs for killing fish parasites, and in particular relates to a compound Chinese herbal medicine preparation for preventing and treating the disease of many-child melon worms, a preparation method and an application thereof. Background technique [0002] Ichthyophthirius multifiliis is a globally distributed parasitic ciliate, which mainly parasitizes the skin, gills and fins of freshwater fish, causing Ichthyophthirius multifiliis, also known as "white spot disease", causing serious damage to the aquaculture industry. Huge economic loss. At present, chemical drugs are mainly used to prevent and control melon worm disease, but chemical drugs have the risk of polluting the environment and endangering human health, especially after malachite green is banned, there is a lack of effective drugs for the prevention and treatment of small melon worm disease on the market. Chinese herbal medicine plants have th...

AI Technical Summary

Problems solved by technology

At present, some plant species resistant to melon worms have been found. Among them, the active compound Erectin C with the best killing effect on melon worms and high safety has been isolated and identified from Baiwei. However, this active compound is in the The content in Bai Wei is only 0.0031%, the cost is too high, it is difficult to commercialize, and the alcohol crude extract of Bai Wei can greatly reduce the cost, and also has good activity of killing small melon insects, but the toxicity of Bai Wei alcohol crude extract Higher, the grass carp suffering from small melon worm disease was treated with the crude extract of Baiwei which was lower than the minimum concentration (8mg / L) to kill small melon worms for 7 days, and all the fish were poisoned and died

Another traditional Chinese medicine, Sophora flavescens, also has the effect of resisting multiseed melon insects. Although the toxicity of its crude extract is low, the activity of killing small melon insects is also low.