Ointment preparation as well as preparation method and application thereof

An ointment and preparation technology, applied in the directions of ointment delivery, anesthetics, anti-inflammatory agents, etc., can solve the problems of slowing down or stopping, unable to take into account hemostasis, pain relief and infection prevention, etc., to reduce pain, not easily induce drug resistance, and antibacterial effect. Enhanced effect

Inactive Publication Date: 2016-11-09
ZHEJIANG REACHALL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, there are several types of medicines for the treatment of skin trauma in China: Western medicine, traditional Chinese medicine, dressing spray, and injection. They have been adopted by hospitals and skin trauma research institutions all over the country.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] An ointment preparation, each gram of the ointment preparation contains: 5000 units of polymyxin B sulfate, 3500 units of neomycin sulfate, 500 units of bacitracin, 2% chitosan (the following are weight percentages), 1% zinc oxide, hydrochloric acid Lidocaine 4%, liquid paraffin 5%, propylene glycol 5%, methyl p-hydroxybenzoate 0.02%, and white petrolatum were added to the prescription amount.

Embodiment 2

[0027] An ointment preparation, each gram of the ointment preparation contains: 5000 units of polymyxin B sulfate, 4000 units of neomycin sulfate, 430 units of bacitracin, 5% chitosan (the following are weight percentages), 3% zinc oxide, hydrochloric acid Procaine 4%, liquid paraffin 7.5%, propylene glycol 4%, methyl p-hydroxybenzoate 0.03%, and white petrolatum were added to the prescription amount.

Embodiment 3

[0029] An ointment preparation, each gram of the ointment preparation contains: 8000 units of polymyxin B sulfate, 3500 units of neomycin sulfate, 400 units of bacitracin, 2% chitosan (the following are weight percentages), 2% zinc oxide, hydrochloric acid Lidocaine 3%, liquid paraffin 6%, propylene glycol 2%, methyl p-hydroxybenzoate 0.01%, and white petrolatum were added to the prescription amount.

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PUM

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Abstract

The invention provides an ointment preparation as well as a preparation method and application thereof, belongs to the technical field of medicine preparations, and is used for solving the problem that a conventional skin injury medicine cannot have take effects of bleeding stopping, pain relieving, infection prevention and the like into account all generally. The ointment preparation comprises a matrix, polymyxin B sulfate, neomycin sulfate, bacitracin and hemostatic, wherein the polymyxin B sulfate, the neomycin sulfate, the bacitracin and the hemostatic are uniformly dispersed in the matrix. Due to synergism of multiple antibiotics in the ointment preparation, not only is a complementary antibacterial spectrum provided, but also the antibacterial range is widened, most skin bacterial infection pathogenic bacteria are covered, and moreover, due to the synergistic and overlapping effect of the antibiotics, the antibacterial function can be enhanced, and induced drug resistance can be avoided. In addition, the ointment preparation comprises local anesthetic and hemostatic, so that a prevention and treatment effect on partial skin bacterial infection can be achieved, functions of pain relieving and bleeding stopping of partial skin wound can be achieved, and patients can be greatly relieved from pain.

Description

technical field [0001] The invention belongs to the technical field of pharmaceutical preparations, and relates to an ointment preparation, a preparation method and an application thereof. Background technique [0002] At present, there are several types of medicines for the treatment of skin trauma in China: Western medicine, traditional Chinese medicine, dressing spray, and injection. They have been adopted by hospitals and skin trauma research institutions all over the country. Clinical data show that the curative effect is average. Wound healing is affected by bacteria, fungi or viruses To slow down or stop, the existing skin trauma medicines generally cannot take into account the effects of hemostasis, pain relief and infection prevention. Contents of the invention [0003] The first object of the present invention is to propose a kind of ointment preparation that takes antibacterial, hemostatic and analgesic effects into consideration for the above-mentioned problems...

Claims

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Application Information

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IPC IPC(8): A61K38/12A61K9/06A61K9/70A61K47/06A61P17/02A61P31/02A61P31/04A61P7/04A61P29/00A61P23/02A61K31/7036A61K31/722A61K33/30A61K33/10A61K33/06A61K31/167A61K31/245
CPCA61K9/06A61K9/7023A61K31/167A61K31/245A61K31/7036A61K31/722A61K33/06A61K33/10A61K33/30A61K38/12A61K47/06A61K2300/00
Inventor 傅龙云张涛铸王富军单含文
Owner ZHEJIANG REACHALL PHARMA
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