Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A bone cement, bio-based technology, applied in tissue regeneration, medical science, prosthesis, etc.
Inactive Publication Date: 2017-02-15
爱本斯南京医疗器械有限公司
View PDF7 Cites 19 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
However, the non-degradability of PMMA itself is destined
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0036] Example 1: Effect of α-Calcium Sulfate Hemihydrate Coated with Different Materials on the Performance of Bone Cement
[0038] (2) Add N,N-dimethyl-p-toluidine (0.75%) and hydroquinone (0.75%) to the pre-mixed MMA (98.5%), dissolve and mix by stirring to obtain bone cement liquid Agent.
[0039] (3) Using a bone cement mixing and mixing system, add the powder first according to the powder-to-liquid mass ratio of 2:1, add the corresponding liquid ingredients, and mix well, the bone cement has 5-8 minutes injection time, and the bone will be obtained after solidification. ...
Embodiment 2
[0044] Example 2: The effect of different initiators in the liquid on the performance of bone cement
[0045] (1) Glutathione-coated α-calcium sulfate hemihydrate (10.6%) and acrylic acid and methyl methacrylate copolymer (70.7%), zirconia (16.7%), and BPO (2%) are mixed uniformly, Obtain bone cement powder.
[0046] (2) Add camphorquinone (1.5%) or N,N-dimethyl-p-toluidine (1.5%) to the premixed MMA (98.5%), dissolve and mix by stirring to obtain a bone cement liquid.
[0047] (3) Using a bone cement mixing and mixing system, add the powder first according to the powder-to-liquid mass ratio of 2:1. After adding the corresponding liquid ingredients and mixing well, the bone cement has 5-8 minutes injection time, and the bone will be obtained after solidification. cement.
[0048] According to the bone cement industry standard, the maximum temperature and curing time of bone cement were measured, the bone cement was injected into a suitable mold and cured for 1 hour, compressive sampl...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention discloses biological bone cement. Calcium sulfate hemihydrate is coated by an absorbable hydrophilic biological material to form micro-spheres, and the micro-spheres are added into acrylic bone cement according to a certain proportion; and in vivo, the calcium sulfate hemihydrate with a surface coated by the absorbable hydrophilic biological material between a tissue and the bone cement is gradually degraded, then a micro-porous structure is formed on the surface of the bone cement, and the biological tissues around continuously fill the micro-pores, so that the contact area between the bone cement and the human body tissue is greatly increased, the fixation strength of the bone cement is enhanced, the incidence of 'bone cement disease' is further reduced, and clinical advantages are obvious.
Description
Technical field [0001] The invention relates to a biological type bone cement. Calcium sulfate hemihydrate is wrapped with absorbable hydrophilic biomaterials to form microspheres, and the microspheres are added to acrylic bone cement in a certain proportion to enhance the biocompatibility of the bone cement. Used in the field of orthopedic materials. Background technique [0002] PMMA bone cement (polymethyl methacrylate) is currently the most clinically used bone cement, which is composed of powder and liquid. The main component of powder is PMMA, and the main component of liquid is MMA (methyl methacrylate) monomer. The current formulations of bone cement on the market are: German one is composed of powder and liquid. Powders include: methyl acrylate-methyl methacrylate polymer, zirconium dioxide, benzoyl peroxide and a small amount of chlorophyll, used for internal fixation of implanted prostheses in joint replacement surgery; liquids include: methyl methacrylate , N, N-Di...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more