Anti-allergic medical pressure-sensitive adhesive and preparation process thereof

A preparation process and pressure-sensitive adhesive technology, which is applied in the field of medical materials, can solve the problems of complex adhesion between pressure-sensitive adhesives and skin, poor air permeability and moisture permeability of pressure-sensitive adhesives, and unfavorable skin perspiration, etc., and achieve the effect of patient experience Excellent, flexible use, high moisture vapor transmission rate effect

Inactive Publication Date: 2017-05-10
SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Pressure sensitive adhesives are used in a variety of applications that need to be bonded to the skin, such as medical tapes, wound or surgical dressings, used to fix instruments or relatively heavy dressings such as indwelling needles, intravenous catheters, etc. on the skin. The flatness of the surface and the existence of hair, secretions, and stratum corneum, the surface properties and mechanical properties of the skin, especially the dynamic mechanical properties, are more different from other materials, which makes the adhesive performance of pressure-sensitive adhesives and skin more complicated.
Usually, in order to increase the bonding ability of the pressure-sensitive adhesive to the skin and reduce warping and shedding, some tackifiers are often added to the pressure-sensitive adhesive. However, the addition of some tackifiers can cause skin allergies. In addition, the commonly used pressure-sensitive The air and moisture permeability of glue is not good, which is not conducive to skin perspiration

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] An anti-allergic medical pressure-sensitive adhesive, prepared from the following raw materials in parts by weight: 34 parts of polyisobutylene, 12 parts of isodecyl acrylate, 6 parts of hydroxy acrylate, 3 parts of glycidyl methacrylate, α-cyano 2 parts of acrylate, 1 part of dithiothreitol, 2 parts of buckwheat flavonoids, 1 part of Tween 80, 1 part of zinc pyrithione, 2 parts of benzyl L-serine, 5 parts of hydrogenated nitrile rubber, 2 parts of mandelic acid , 3 parts of menthol, 5 parts of peach gum, 4 parts of hydroxypropyl-β-cyclodextrin, 1.2 parts of vitamin E, 0.6 parts of initiator, and 1.4 parts of plasticizer.

[0023] Wherein, the initiator is benzoyl peroxide.

[0024] Wherein, the plasticizer is glycerol.

[0025] A preparation process of anti-allergic medical pressure-sensitive adhesive, comprising the following preparation steps:

[0026] Step 1) Mix hydrogenated nitrile rubber, L-serine benzyl ester and a-cyanoacrylate evenly, and then banbury at 110...

Embodiment 2

[0032] An anti-allergic medical pressure-sensitive adhesive, prepared from the following raw materials in parts by weight: 45 parts of polyisobutylene, 22 parts of isodecyl acrylate, 15 parts of hydroxy acrylate, 3-9 parts of glycidyl methacrylate, a- 5 parts of cyanoacrylate, 6 parts of dithiothreitol, 5 parts of buckwheat flavonoids, 3 parts of Tween 80, 4 parts of zinc pyrithione, 6 parts of benzyl L-serine, 9 parts of hydrogenated nitrile rubber, mandelic acid 7 parts, menthol 6 parts, peach gum 12 parts, hydroxypropyl-β-cyclodextrin 8 parts, vitamin E 3 parts, initiator 1.8 parts, plasticizer 2.2 parts.

[0033] Wherein, the initiator is tetramethylethylenediamine.

[0034] Wherein, the plasticizer is sorbitol.

[0035] A preparation process of anti-allergic medical pressure-sensitive adhesive, comprising the following preparation steps:

[0036] Step 1) Mix hydrogenated nitrile rubber, L-serine benzyl ester and a-cyanoacrylate evenly, and then banbury at 140°C for 10 m...

Embodiment 3

[0042] An anti-allergic medical pressure-sensitive adhesive, prepared from the following raw materials in parts by weight: 36 parts of polyisobutylene, 14 parts of isodecyl acrylate, 7.5 parts of hydroxy acrylate, 3.5 parts of glycidyl methacrylate, a-cyano 2.4 parts of acrylate, 1.2 parts of dithiothreitol, 2.4 parts of buckwheat flavonoids, 1.4 parts of Tween 80, 1.8 parts of zinc pyrithione, 2.7 parts of L-serine benzyl ester, 5.2 parts of hydrogenated nitrile rubber, 2.4 parts of mandelic acid , 3.4 parts of menthol, 5.5 parts of peach gum, 4.2 parts of hydroxypropyl-β-cyclodextrin, 1.5 parts of vitamin E, 0.8 parts of initiator, and 1.6 parts of plasticizer.

[0043] Wherein, the initiator is benzoin dimethyl ether.

[0044] Wherein, the plasticizer is mannose.

[0045] A preparation process of anti-allergic medical pressure-sensitive adhesive, comprising the following preparation steps:

[0046] Step 1) Mix hydrogenated nitrile rubber, L-serine benzyl ester and a-cyano...

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PUM

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Abstract

The invention discloses an anti-allergic medical pressure-sensitive adhesive and a preparation process thereof. The pressure-sensitive adhesive is prepared from the following raw materials: polyisobutene, isodecyl acrylate, acrylate-hydroxy ester, glycidyl methacrylate, alpha-cyanoacrylate, dithiothreitol, buckwheat-flavonoids, Tween 80, pyrithione zinc, L-serine benzyl ester, hydrogenated butadiene-acrylonitrile rubber, mandelic acid, menthol, peach gum, hydroxypropyl-beta-cyclodextrin, vitamin E, an initiator and plasticiser. The medical pressure-sensitive adhesive prepared by the invention presents a higher moisture-vapor transmission rate and moderate viscosity, can be used for repeatedly removing a label for more than 5 times, is flexible to use, has good compatibility with the skin, and has no stimulation to the skin and no allergic phenomenon, the experience effect of a patient is better, and the applied range is wide.

Description

technical field [0001] The invention belongs to the technical field of medical materials, and in particular relates to an anti-allergic medical pressure-sensitive adhesive and a preparation process thereof. Background technique [0002] Pressure sensitive adhesives are used in a variety of applications that need to be bonded to the skin, such as medical tapes, wound or surgical dressings, used to fix instruments or relatively heavy dressings such as indwelling needles, intravenous catheters, etc. on the skin. The flatness of the surface and the existence of hair, secretions, cuticle, and the surface properties, mechanical properties, especially the dynamic mechanical properties of the skin are more different from other materials, which makes the adhesive performance of the pressure-sensitive adhesive and the skin more complicated. Usually, in order to increase the bonding ability of the pressure-sensitive adhesive to the skin and reduce warping and shedding, some tackifiers ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C09J123/20C09J133/08C09J11/06C09J11/08
CPCC08L2205/035C09J11/06C09J11/08C09J123/22C09J2301/302C08L33/08C08L15/005C08L5/16C08K5/053
Inventor 李子寅祁帆
Owner SUZHOU AIBOMAIER NEW MATERIAL CO LTD
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