Medicinal composition containing lentinan, and preparation method and use thereof

A technology of lentinan and a composition is applied in the field of pharmaceutical compositions for enhancing immunity of livestock and poultry and the field of preparation thereof, which can solve the problems of increasing the susceptibility to various infectious diseases, reducing the immune reactivity of animals, damaging the immune system of the body, and the like, and achieving Significant immunosuppression and dysfunction, simple clinical administration, and saving manpower and material resources

Inactive Publication Date: 2017-05-24
胡大坤
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, under the background of today's breeding environment, diseases occur from time to time, especially viral diseases of livestock and poultry such as chicken bursal disease, chicken Newcastle disease, swine fever, circovirus disease, etc., which can easily induce immunosuppressive diseases, causing animals Reduced immune reactivity and damage to the body's immune system not only seriously affect productivity, but also increase the sensitivity of animals to bacteria, viruses, parasites, etc., reduce the effect of immunization, increase susceptibility to various infectious diseases, aggravate disease symptoms, and even die
At present, veterinary clinics lack effective drugs against immunosuppressive diseases of livestock and poultry

Method used

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  • Medicinal composition containing lentinan, and preparation method and use thereof
  • Medicinal composition containing lentinan, and preparation method and use thereof
  • Medicinal composition containing lentinan, and preparation method and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1. is used for the preparation of the Chinese medicine composition of enhancing immunity

[0032] Prepare as follows:

[0033] (1) Take lentinan (Jiangsu Nanjing Nongda Animal Pharmaceutical Co., Ltd.), yeast dextran (Zhengzhou Hongxiang Chemical Products Co., Ltd.), and licorice extract (Zhengzhou Kangzhiyuan Chemical Products Co., Ltd.), and ultrafinely pulverize them after drying To 600 orders; Get levamisole hydrochloride (Henan Huijin Pharmaceutical Co., Ltd.), dry and ultrafinely pulverize to 1000 orders; Get anhydrous glucose (Shanxi Xiwang Pharmaceutical Co., Ltd.), dry, pulverize, and cross 80 mesh sieves;

[0034] (2) Accurately weigh 5g of lentinan and mix with 5g of anhydrous glucose, then mix with 10g of yeast dextran, and then mix with 50g of licorice extract to obtain mixture A;

[0035] (3) Accurately weigh 20g of levamisole hydrochloride and mix with 30g of anhydrous glucose to obtain mixture B;

[0036] (4) Mix the mixtures A and B evenly,...

Embodiment 2

[0038] Example 2. Preparation of Chinese medicine composition for enhancing immunity

[0039] Prepare as follows:

[0040] (1) Take lentinan, yeast dextran, and licorice extract, and after drying, ultrafinely pulverize them to 600 mesh respectively; take levamisole hydrochloride, and ultrafinely pulverize them to 1000 mesh after drying; take anhydrous glucose, dry, pulverize, pass 80 mesh sieve;

[0041] (2) Accurately weigh 10g of lentinan and mix with 10g of anhydrous glucose, then mix with 20g of yeast glucan, and then mix with 100g of licorice extract to obtain mixture A;

[0042] (3) Accurately weigh 50g of levamisole hydrochloride and 50g of anhydrous glucose and mix uniformly to obtain mixture B;

[0043] (4) Mix the mixtures A and B evenly, and then mix them evenly with the remaining amount of anhydrous glucose according to the equal volume incremental dilution method to obtain 1000 g of the pharmaceutical composition of the present invention;

[0044] (5) 100g / bag,...

Embodiment 3

[0045] Example 3. Preparation of Chinese medicine composition for enhancing immunity

[0046] Prepare as follows:

[0047] (1) Take lentinan, yeast dextran, and licorice extract, and after drying, ultrafinely pulverize them to 600 mesh respectively; take levamisole hydrochloride, and ultrafinely pulverize them to 1000 mesh after drying; take anhydrous glucose, dry, pulverize, pass 80 mesh sieve;

[0048] (2) Accurately weigh 40g of lentinan and mix with 40g of anhydrous glucose, then mix with 80g of yeast glucan, and then mix with 160g of licorice extract to obtain mixture A;

[0049] (3) Accurately weigh 80g of levamisole hydrochloride and mix with 80g of anhydrous glucose to obtain mixture B;

[0050] (4) Mix the mixtures A and B evenly, and then mix them evenly with the remaining amount of anhydrous glucose according to the equal volume incremental dilution method to obtain 1000 g of the pharmaceutical composition of the present invention;

[0051](5) 100g / bag, packed se...

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Abstract

The invention discloses a medicinal composition containing lentinan. The medicinal composition comprises, by weight, 0.5-5% of lentinan, 1-10% of yeast glucan, 2-10% of levamisole hydrochloride, 5-30% of licorice root extract, and the balance of anhydrous glucose. The invention also discloses a preparation method of the medicinal composition, and a use of the composition in enhancement of the immunity of animals. The medicinal composition which is processed through an ultrafine crushing technology has a high medicine absorption rate, substantially promotes the growth of animal immune organs and enhances the immunity of animal bodies; the medicinal composition has a substantial curative effect on viral disease induced immunosuppression and poor immunity, and substantially reduces the mortality of pathogenetic animals; the medicinal composition substantially increases the antibody tilter of vaccine immunized serum of the animals in order to substantially enhance the vaccine immunization effect; and the composition has the advantages of simple production steps, convenience in clinic use, and convenience in colony administration.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and mainly relates to a pharmaceutical composition containing lentinan for enhancing immunity of livestock and poultry bodies and a preparation method thereof. Background technique [0002] In recent years, with the rapid development of large-scale and intensive farming, the science and technology for the prevention and control of livestock and poultry breeding diseases are also developing rapidly. However, under the background of today's breeding environment, diseases occur from time to time, especially viral diseases of livestock and poultry such as chicken bursal disease, chicken Newcastle disease, swine fever, circovirus disease, etc., which can easily induce immunosuppressive diseases, causing animals Reduced immune reactivity and damage to the body's immune system not only seriously affect productivity, but also increase the sensitivity of animals to bacteria, viruses, parasites, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61P37/04A61P31/14A61K31/715A61K31/429A61K31/716
Inventor 胡大坤
Owner 胡大坤
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