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Composition for assistedly decreasing blood sugar, and preparation method and application thereof

A composition and blood sugar-lowering technology, which can be used in application, drug combination, medical preparations containing active ingredients, etc., can solve the problems of side effects and body damage, zero complications, etc.

Active Publication Date: 2017-05-24
YUNNAN DECAITANG BIOMEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Diabetes is a systemic progressive disease caused by blood sugar out of control and higher than the normal level. There are many and serious complications. In addition to insulin injection, the clinical treatment is mainly oral sulfonylurea and biguanide hypoglycemic drugs. There are certain side effects and body damage
At present, there are few health care products that effectively lower blood sugar, assist in the prevention and treatment of diabetes, and are not in line with the national "preventive treatment" health industry policy

Method used

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  • Composition for assistedly decreasing blood sugar, and preparation method and application thereof
  • Composition for assistedly decreasing blood sugar, and preparation method and application thereof
  • Composition for assistedly decreasing blood sugar, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: Preparation of Cyclocarya paliurus extract

[0023] Take Cyclocarya paliurus leaves, remove impurities, dry, crush and pass through a 24-mesh sieve. Weigh 10 kg of Cyclocarya paliurus leaf coarse powder and place it in an extraction tank, add ethanol with a mass volume ratio (g / ml)=1:3, and a concentration of 75% under reflux to extract twice (temperature control 80°C, 3 hours each time), Combine the two extracts and concentrate under reduced pressure to a relative density of 1.05 (measured at 20°C) to obtain a concentrated solution containing flavonoids and saponins; the remaining residue is weighed after the ethanol heat reflux extraction, and the mass volume ratio (g / ml) = 1 : 8 decoctions in purified water for 2 times (temperature control 90°C, each extraction for 2 hours), combine the 2 extracts and concentrate under reduced pressure to a relative contrast of 1.23 (measured at 20°C) to obtain a concentrated solution containing polysaccharides; combine...

Embodiment 2

[0025] Embodiment 2: Preparation of Moringa Leaf Ultrafine Broken Wall Fine Powder

[0026] Start the low-temperature pulverizer (Gaoqiao / M-250 type) with liquid nitrogen flow and pre-cool it to -20°C, weigh 1.5 kg of dried Moringa oleifera leaves (moisture content ≤ 10%), put it in the pulverizer, and pulverize it to 1000 mesh when it is started. Obtain 1.25kg of Moringa oleifera leaf supermicro-broken fine powder.

Embodiment 3

[0027] Embodiment 3: preparation of mulberry leaf extract and bitter melon extract

[0028] Purchase specification is 1.5kg of food grade mulberry leaf extract of 1:10. Self-test flavonoid content 6%, DNJ content 1.8%.

[0029] Purchase 1 kg of Momordica charantia glycosides content ≥ 10% food grade bitter melon extract (Q / HLB031-2013). The content of Momordica glycosides in self-test is 13%.

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Abstract

The invention discloses a composition for efficiently assistedly decreasing blood sugar, and a preparation method and an application thereof. The composition is composed of 400 to 500 parts by weight of a cyclocarya paliurus extract, 200 to 300 parts by weight of a horseradish tree leaf ultramicro wall-broken fine powder, 120 to 240 parts by weight of a mulberry leaf extract and 80 to 160 parts by weight of a bitter gourd extract. The content of cyclocarya paliurus total flavonoids is 8-16% and the content of polysaccharides is 12 to 28%; horseradish tree leaves are subjected to low-temperature airflow crushing to obtain the ultramicro wall-broken powder; the content of total flavonoids of the mulberry leaf extract is 2% to 15%, and the content of DNJ is 1% to 2%; the content of charantin of the bitter gourd extract is 5% to 20%. Tests indicate that the composition can significantly reduce the blood sugar of diabetic mice, can significantly enhance the glucose tolerance of the diabetic mice, and has important significance for research and development of hypoglycemic drugs, health food, functional ordinary food, special medical food and special dietary food.

Description

technical field [0001] The invention relates to a high-efficiency auxiliary hypoglycemic composition. In particular, it relates to a compatible composition of Cyclocarya paliurus extract, ultrafine broken wall fine powder of Moringa leaf, mulberry leaf extract and bitter melon extract, as well as its preparation method and application. [0002] technical background [0003] Due to the continuous improvement of people's living standards, changes in diet structure, increasingly tense pace of life, and a less active and more sedentary lifestyle and many other factors, the incidence of diabetes worldwide has increased very rapidly. According to statistics, diabetes has become the third chronic disease that seriously threatens human health after tumors and cardiovascular and cerebrovascular diseases. Diabetes is a systemic progressive disease caused by blood sugar out of control and higher than the normal level. There are many and serious complications. In addition to insulin inj...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61P3/10A23L33/105
CPCA23V2002/00A61K36/185A61K36/42A61K36/52A61K36/605A61K2236/331A61K2236/333A61K2236/39A61K2300/00A23V2200/328A23V2250/21
Inventor 龙祥潘丽婷卢阳辉洪早梅张伟平
Owner YUNNAN DECAITANG BIOMEDICAL TECH
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