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Essence containing recombinant human metallothionein fermentation product extract and application of essence in cosmetic

A technology of metallothionein and fermented products, applied in cosmetics, cosmetic preparations, cosmetic preparations, etc., can solve the problems of high price of metallothionein and increased production cost of cosmetics, etc.

Inactive Publication Date: 2017-05-31
GUANGZHOUJIDABIOLOGICAL TECH CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, metallothionein is expensive, which greatly increases the production cost of this type of cosmetics

Method used

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  • Essence containing recombinant human metallothionein fermentation product extract and application of essence in cosmetic
  • Essence containing recombinant human metallothionein fermentation product extract and application of essence in cosmetic
  • Essence containing recombinant human metallothionein fermentation product extract and application of essence in cosmetic

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Example 1. Preparation of a yeast fermentation product extract essence comprising recombinant human metallothionein

[0072] The present invention provides a method for preparing a yeast fermentation product extract essence comprising recombinant human metallothionein, and the mass percentage of each component is as follows:

[0073] Table 1

[0074]

[0075] Add tranexamic acid, amino acid moisturizer, Usnea barbadensis extract, and Pepper fruit extract to an appropriate amount of ultrapure water according to the prescribed amount, mix well to make solution A; add the amounts shown in Table 1 to solution A in turn D-panthenol, yeast fermentation product extract of recombinant human metallothionein, oligopeptide-1, supplemented with water and stirred evenly.

[0076] Among them, recombinant human metallothionein yeast fermentation product extract and oligopeptide-1 were prepared or synthesized by the Medical Biotechnology Research and Development Center of Jinan Uni...

Embodiment 2

[0077] Example 2. Preparation of a liquid crystal essence containing recombinant human metallothionein yeast fermentation product extract

[0078] The present invention provides a method for preparing a liquid crystal essence containing recombinant human metallothionein yeast fermentation product extract, and the mass percentage of each component is as follows:

[0079] Table 2

[0080]

[0081] Step 1, 3% by weight of cetyl alcohol, 3% by weight of stearyl alcohol, 2% by weight of glyceryl monostearate, and 2% by weight of cetearyl glucoside are mixed and heated to 70-75 °C to completely dissolve and maintain at 75 °C to obtain phase A;

[0082] Step 2: Mix 5% by weight of white oil and 2% by weight of caprylic acid glycerin, heat to 70-75°C to completely dissolve and maintain at 75°C to obtain Phase B;

[0083] Step 3: Mix phase A and phase B uniformly at a volume ratio of 1.4:1, and maintain the temperature at 75°C to obtain phase C;

[0084] Step 4, 20% by weight of ...

Embodiment 3

[0088] Example 3. A lotion comprising an essence containing recombinant human metallothionein

[0089] The present invention provides a lotion containing an essence containing recombinant human metallothionein yeast fermentation product extract, the mass percentage of each component is as follows:

[0090] table 3

[0091]

[0092] Dissolve nicotinamide, hyaluronic acid, glycerin, and licorice extract in ultrapure water according to the prescription amount and mix them evenly, then add the essence prepared in Example 1 containing recombinant human metallothionein yeast fermentation product extract to adjust the pH When the value reaches 7.0-7.4, add the remaining ultrapure water and stir evenly.

[0093] Among them, tea polyphenols and licorice extract were purchased from Shaanxi Senfu Natural Products Co., Ltd.; nicotinamide, hyaluronic acid, glycerin, and phenoxyethanol were purchased from Hunan Erkang Pharmaceutical Co., Ltd.

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Abstract

The invention relates to a composition employing a recombinant human metallothionein fermentation product extract as a core active ingredient and different preparation forms of the composition. The composition is characterized by comprising the recombinant human metallothionein fermentation product extract, oligopeptide-1, a freeze drying agent employing tranexamic acid as a main ingredient, a solution and a liquid crystal essence, wherein the amino acid sequence of recombinant human metallothionein is as shown in SEQ ID No.1; and the amino acid sequence of the oligopeptide-1 is as shown in SEQ ID No.1. The essence has the effects of reducing wrinkles, whitening the skin, moisturizing the skin and preventing ultraviolet radiation; microelements of Zn, Fe, Cu and the like can be supplemented at the same time by removing free radicals of the skin to adjust local microcirculation of the skin and to promote skin repairing and healing, thereby achieving the target of whitening the skin. In addition, the metallothionein has a special function of combining heavy metals; and the essence has a particular effect on makeup people with skin injuries of stains and wrinkles caused by cosmetic pigments containing the heavy metals.

Description

technical field [0001] The invention belongs to the field of cosmetics. Specifically, the present invention relates to an essence containing metallothionein fermented product extract and its cosmetic composition. The protein has a special function of binding heavy metals. This essence has a special effect on the makeup crowd who have skin damage such as spots and wrinkles caused by heavy metal makeup pigments. Background technique [0002] With age, a series of chronic, progressive and degenerative changes appear in the tissues, organs and cell functional structures of the body, which have adverse effects on the body, resulting in a gradual decline in its adaptability and reserve capacity. This process of change continues Occurrence and development is aging. [0003] The obvious sign of aging is skin aging, which is typically manifested by the appearance of age spots, itching, dryness, roughness or dermatitis. Studies have found that the existence of free radicals in the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/64A61K8/44A61Q19/08A61Q19/02A61Q19/00A61Q17/04
CPCA61Q17/04A61Q19/00A61Q19/02A61Q19/08A61K8/44A61K8/64A61K2800/85Y02A50/30
Inventor 黄亚东项琪肖巧学薛来武
Owner GUANGZHOUJIDABIOLOGICAL TECH CO LTD
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