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Hygroscopic antibacterial hydrocolloid dressing and preparation method thereof

A hydrocolloid and preparation technology, applied in medical science, bandages, etc., can solve the problems of skin barrier loss of integrity, fluid leakage, etc., and achieve the effects of improving mechanical properties, reducing cold flow, and improving integrity

Inactive Publication Date: 2017-05-31
GUANGDONG TAIBAO MEDICAL DEVICE TECH RES INST CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Loss of integrity of the skin barrier, causing fluid leakage, frequent dressing changes, and residual material that is often left on the skin

Method used

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  • Hygroscopic antibacterial hydrocolloid dressing and preparation method thereof
  • Hygroscopic antibacterial hydrocolloid dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] A preparation method of a hygroscopic antibacterial hydrocolloid dressing, the specific preparation process steps of the preparation method are:

[0026] (1) Ingredients: 10 parts by weight of styrene-isoprene-styrene block copolymer elastomer, 5 parts of vitamin C antioxidant, 50 parts of water-soluble hydrocolloid, 20 parts of Dioctyl dioate plasticizer, 10 parts of tackifier and 5 parts of liquid paraffin softener are mixed and added to the extruder in turn; the water-soluble hydrocolloid is carboxymethyl chitosan quaternary The mixture of ammonium salt, sodium alginate, sodium carboxymethyl cellulose, grafted acrylamide and cross-linked hydroxyethyl cellulose grafted acrylamide polymer in a mass ratio of 1:1:1:1:1, said The tackifier is a mixture of disproportionated rosin ester and terpene resin in a mass ratio of 1:1;

[0027] (2) Extrusion: heat and extrude the material prepared in step (1) in the extruder. The extrusion conditions are: the heating range of the ...

Embodiment 2

[0032] A preparation method of a hygroscopic antibacterial hydrocolloid dressing, the specific preparation process steps of the preparation method are:

[0033] (1) Ingredients: 30 parts by weight of polyurethane rubber elastomer, 1 part of vitamin C antioxidant, 10 parts of water-soluble hydrocolloid, 30 parts of tributyl citrate plasticizer, 25 parts of C9 Petroleum resin tackifier and 4 parts of softener are mixed and added to the extruder in turn; the water-soluble hydrocolloids are carboxymethyl chitosan quaternary ammonium salt, sodium alginate, carboxymethyl cellulose A mixture of sodium, grafted acrylamide, and cross-linked hydroxyethyl cellulose grafted acrylamide polymer in a mass ratio of 4:4:2:1:1, and the softener is vegetable oil and white vaseline in a mass ratio of 2 : a mixture of 1;

[0034] (2) Extrusion: heat and extrude the material prepared in step (1) in the extruder. The extrusion conditions are: the heating range of the extrusion area is 150°C, the he...

Embodiment 3

[0039] A preparation method of a hygroscopic antibacterial hydrocolloid dressing, the specific preparation process steps of the preparation method are:

[0040] (1) Ingredients: 15 parts by weight of polyacrylate elastomer, 10 parts of vitamin C antioxidant, 30 parts of water-soluble hydrocolloid, 5 parts of polyisobutyl ester plasticizer, 40 parts of terpene The olefin resin tackifier is mixed and added to the extruder in turn; the water-soluble hydrocolloid is carboxymethyl chitosan quaternary ammonium salt, sodium alginate, sodium carboxymethyl cellulose, grafted acrylamide , a mixture of cross-linked hydroxyethyl cellulose grafted acrylamide polymer in a mass ratio of 2:2:1:1:1;

[0041] (2) Extrusion: heat and extrude the material prepared in step (1) in the extruder. The extrusion conditions are: the heating range of the extrusion area is 120°C, the head temperature is 110°C, and the main engine speed is 50rpm. The feeding speed is 20rpm, and it becomes a block or strip...

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Abstract

The invention belongs to the field of medical biopolymer materials and particularly relates to a hygroscopic antibacterial hydrocolloid dressing and a preparation method thereof. The preparation method comprises the steps of burdening, extruding, secondary extrusion, injection molding and ageing molding in sequence to prepare a hygroscopic antibacterial hydrocolloid dressing product. The preparation technology is simple and easy to process and massive production is easy to implement; the prepared hygroscopic antibacterial hydrocolloid dressing is capable of absorbing a lot of seepage and creating a humid microenvironment for wound healing; meanwhile, the contained sodium alginate and quaternized carboxymethyl chitosan are fully mixed and then form more hydrogen bonds, so that the gelatinization reaction is strengthened, the hydrocolloid dressing is capable of keeping relatively good integrity after absorbing a lot of wound seepage, is not sticky to a wound and has certain elasticity, antibacterial property and autohension; the comfort level of a patient is improved; and healing of the wound is accelerated.

Description

technical field [0001] The invention belongs to the technical field of preparation of medical biopolymer materials, in particular to a hygroscopic antibacterial hydrocolloid dressing and a preparation method thereof. Background technique [0002] A hydrocolloid dressing is a dressing that contains gelatinous substances, such as sodium carboxymethylcellulose (NaCMC) and gelatin (Gelatin). Most products also add elastic polymers and adhesives, which are placed on the carrier (The carrier is usually a polyurethane foam or film), resulting in an absorbent, self-adhesive, waterproof dressing sheet that is opaque or translucent, biodegradable, and has good adhesion, so no additional tape is required for fixation. Available in different thicknesses and shapes for different wounds and anatomical sites. In addition, hydrocolloid dressings are easy to cut and can be tailored to the anatomical site for best results. [0003] Hydrocolloid dressings are one of the most commonly used ad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/008A61L26/0014A61L26/0023A61L26/0061A61L26/0066A61L2300/232A61L2300/404C08L5/08C08L1/286C08L5/04C08L33/26
Inventor 卢亢陈锦涛熊亮
Owner GUANGDONG TAIBAO MEDICAL DEVICE TECH RES INST CO LTD
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