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A traditional Chinese medicine composition for preventing and treating rainbow trout hepatobiliary syndrome and its preparation method

A technology for hepatobiliary syndrome and composition, which is applied in the field of aquatic veterinary medicine, can solve the problems of insufficient nutrient composition of feeding bait, difficult discharge of ammonia metabolites, damage to liver function, etc., so as to improve the survival rate and quality, improve the bioavailability, The effect of enhancing pharmacodynamic activity

Inactive Publication Date: 2020-10-13
SOUTHWEST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

my country's rainbow trout farming is mainly distributed in Beijing, Heilongjiang, Shandong, Shanxi, Liaoning, Jilin, Shaanxi and other places. In recent years, the industry has developed rapidly. However, due to the lagging research on its nutrition and disease control, the breeding process is often prone to nutrient components in the feeding bait. Hepatic steatosis, vitamin deficiency and other diseases caused by deficiency
[0004] There are many factors causing rainbow trout hepatobiliary syndrome, such as nutritional causes: such as lack of choline, V E , Biotin, Inositol, V B etc., causing fat metabolism disorder in the fish, leading to fat accumulation in the liver and inducing pathological changes; or unreasonable nutritional ratio of feed, high protein content, high carbohydrate content in feed, or long-term use of animal fat and highly saturated fatty acid Etc., resulting in high energy-protein ratio of feed, easy to induce liver fat accumulation, damage liver function, and lead to the occurrence of hepatobiliary syndrome; caused by poor management: if the feed is moldy and deteriorated, the toxic substances produced will directly harm the liver of fish
In addition, the deterioration of the water quality environment makes it difficult to excrete the ammonia metabolites in the fish, which can also easily cause the metabolic imbalance of the fish and lead to the occurrence of liver and gallbladder diseases
At the same time, adding low-dose chemical drugs to the feed for a long time or using fish medicines with large side effects and high residues will also cause damage to the liver and gallbladder of fish and induce liver diseases.
[0005] At present, the conventional prevention and control method in the market is to add vitamins and choline to the feed to prevent and control, but the effect is not particularly ideal. However, the compound preparations of Chinese veterinary medicines such as Gandan Likang San and Chaihuang Yigan San are due to the process and the mechanism of the digestive tract of fish. Therefore, it is the focus of current research to find a safe, efficient and non-resistant treatment method.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The traditional Chinese medicine composition for preventing and treating hepatobiliary syndrome of rainbow trout: 10 parts of capillary, 5 parts of turmeric, 5 parts of Eucommia, 5 parts of isatidis, 5 parts of mango leaves, and 3 parts of neem root.

[0022] The preparation method of Chinese medicine composition is:

[0023] 1) Dry and pulverize the above-mentioned mango leaves, use 9 times the amount of ethanol to reflux extract twice, each time for 3 hours, combine the extracts obtained each time, recover the solvent, and dry in a vacuum drying oven at 50°C to obtain the mango leaf extract;

[0024] 2) crush the above-mentioned neem root, extract by cold soaking with 95% methanol for 3 times, each time for 4-5 hours, combine the extracts obtained each time, concentrate under reduced pressure until no methanol is evaporated, and obtain the neem root extract;

[0025] 3) Weigh capillary, turmeric, Eucommia, and Radix Radix, mix, crush and sieve into 40-mesh powder, put...

Embodiment 2

[0029] The traditional Chinese medicine composition for preventing and treating hepatobiliary syndrome of rainbow trout has the following components: 15 parts of capillary, 7 parts of turmeric, 10 parts of Eucommia, 8 parts of isatidis, 10 parts of mango leaves, and 5 parts of neem root.

[0030] Its preparation method is identical with embodiment 1.

Embodiment 3

[0032] A traditional Chinese medicine composition for preventing and treating rainbow trout hepatobiliary syndrome,

[0033] 20 parts of capillary, 10 parts of turmeric, 15 parts of Eucommia, 15 parts of Radix Isatidis, 15 parts of mango leaves, and 10 parts of neem root. Its preparation method is identical with embodiment 1.

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PUM

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Abstract

The invention provides a traditional Chinese medicinal composition for preventing and treating hepatobiliary syndromes in oncorhynchus mykiss. The traditional Chinese medicinal composition consists of the following traditional Chinese medicinal components in parts by weight: 10-20 parts of herba artemisiae scopariae, 5-10 parts of radix curcumae, 5-15 parts of cortex eucommiae, 5-15 parts of radix isatidis, 5-15 parts of folium mangiferae and 3-10 parts of azadirachta indica root. The traditional Chinese medicinal composition for preventing and treating the hepatobiliary syndromes in oncorhynchus mykiss provided by the invention, through compatibility of the raw materials, is efficient, safe, green and environment-friendly; and the traditional Chinese medicinal composition is especially suitable for preventing and treating such hepatobiliary syndromes as pathological change in liver and gallbladder, nutritional fatty liver, liver and gallbladder enlargement and the like caused by bacteria.

Description

technical field [0001] The invention belongs to the field of aquatic veterinary medicine, and in particular relates to a traditional Chinese medicine composition for preventing and treating rainbow trout hepatobiliary syndrome. Background technique [0002] Rainbow trout, commonly known as trout, is native to western North America and is an imported species in China. Because there are no thorns in the meat, it is easy to digest, rich in vitamin D, iron content, highly unsaturated fatty acids, especially 22 carbon 6 enoic acid and 20 carbon 5 enoic acid. The former can help brain development and growth, activate brain cells, delay The effect of brain aging, the latter has the effect of lowering blood fat, preventing arteriosclerosis, myocardial infarction and cerebral apoplexy, fish skin is rich in protein, has the effect of beautifying and strengthening muscles and bones, besides, it also contains essential amino acids and minerals that can supply the human body , vitamin A...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P1/16A61P31/04
CPCA61K36/195A61K36/22A61K36/282A61K36/315A61K36/46A61K36/58A61K36/9066A61K2236/33A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 周朝伟朱成科郑宗林曾本和雷骆王宵周燕
Owner SOUTHWEST UNIV
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