Drug composition for preanesthesia operation nursing and application of drug composition

Abstract

The invention relates to a drug composition for preanesthesia operation nursing and application of the drug composition. The drug composition comprises Imidafenacin or medicinal drug thereof, tetrahydropalmatine and/or gentianine. Various components of the drug composition are synergistic after being combined, so that the application dose of a single component in the combination is reduced, the feeling threshold of the operation patient can be effectively improved, the dose of the anaesthetic for the operation can be reduced, the adverse effect caused by the anaesthetic can be effectively alleviated, the anxiety of the patient can be alleviated, saliva and respiratory secretions of the patient can be reduced, and the pulmonary complications in the operation and after the operation can be prevented; and therefore, the drug composition can be widely used for the preanesthesia operation nursing.

Description

technical field [0001] The invention belongs to the field of medicines, and in particular relates to a pharmaceutical composition used for nursing before anesthesia in an operation and its application. Background technique [0002] In today's highly developed medical care, surgery has become a fast, direct and effective treatment for many diseases. Since doctors need to use medical instruments to perform destructive operations such as excision and suture on patients during surgery, patients need to be anesthetized before surgery to Reduce the pain of the patient and ensure the smooth progress of the operation. [0003] On the one hand, the development of anesthesiology ensures the smooth progress of the operation, but the anesthesia itself has serious complications, such as vomiting and regurgitation of the patient under anesthesia, which may cause acute airway obstruction in the patient, and in severe cases will lead to the patient's death. Death, postoperative nausea, vom...

AI Technical Summary

Problems solved by technology

Nursing before surgical anesthesia currently has different methods such as psychological nursing and drug nursing. Among them, drug nursing before surgical anesthesia generally uses certain drugs to relieve the patient's tension and improve the patient's pain threshold before anesthesia. Currently known pre-anesthesia intervention drugs include changtoning, atropine, scopolamine, midazolam, etc. The administration of the above drugs relieves the patient’s tension to a certain extent and reduces the adverse reactions during anesthesia, but the above drugs There are also adverse reactions such as excessive sedation, laryngospasm, and cardiovascular complications, which restrict their use to a certain extent

[0005] In order to overcome the adverse reactions of currently known pre-anesthesia intervention drugs, some literatures have reported the advantages of using traditional Chinese medicines with low side effects, and using them for nursing before surgical anesthesia. For example, patent CN104173883 discloses a pre-anesthesia intervention drug. Alpine ginger, safflower parasites, piercing stones, reed stems, golden buckwheat stems and leaves, motherwort, coix seed, kudzu root, honeysuckle, mulberry, antler gum, scallion white, but traditional Chinese medicine also has defects such as complex ingredients and slow onset of action. There are also reports in the literature that the combination of Chinese and Western medicines is used for nursing before surgical anesthesia. For example, the patent CN105535489 discloses a kind of traditional Chinese medicine that contains the main ingredients of Chinese medicines: brevescarpa fruit, bitter cauliflower, Guanyin bamboo, calf force, and echinacea. , Fushenmu, Myrobalan, Sedum notoginseng, valerian, sandalwood extract, Chrysanthemum chrysanthemum extract; the main ingredients of western medicine are: aminomethylbenzoic acid, lysine, taurine, cefuroxime for surgical anesthesia Pre-care pharmaceutical composition, but the pharmaceutical ingredients used are more complex

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