Traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and preparation method of traditional Chinese medicine preparation

A technology for insomnia, forgetfulness, and traditional Chinese medicine preparations, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It can solve problems such as unsatisfactory and incomplete extraction of active ingredients, and achieve low production costs. , Guarantee the content and curative effect of active ingredients, and improve the effect of curative effect

Inactive Publication Date: 2017-11-07
广西大海阳光药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The extraction process of the patent "a traditional Chinese medicine preparation with nourishing blood and calming nerves and its preparation method" (application number 200510003181.4) is as follows: the medicinal materials are extracted with water, concentrated, and then subjected to alcohol precipitation twice to remove impurities. Alcohol removed impurities twice, but the Radix Polygoni Multiflori medicina

Method used

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  • Traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and preparation method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and preparation method of traditional Chinese medicine preparation
  • Traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and preparation method of traditional Chinese medicine preparation

Examples

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Example Embodiment

[0080] Example 1

[0081] A preparation method of dispersible tablets prepared from a traditional Chinese medicine preparation for treating dizziness, palpitations, insomnia and forgetfulness, includes the following steps:

[0082] T1. Take the following components: hydroxypropyl methyl cellulose, pregelatinized starch, crospovidone, sodium carboxymethyl starch, sodium lauryl sulfate, micronized silica gel, crushed through a 100 mesh sieve, and set aside ;

[0083] T2. Weigh the components according to the following parts by weight: Agrimony 800g, Eclipta prostrata 400g, Cortis spatholobi 400g, Rehmannia glutinosa 400g, Rehmannia glutinosa 400g, Albizia julibrissin 400g, Shouwu vine 450g, Sodium alginate 300g, Hypromellose Base cellulose 100g, calcium sulfate 200g, crospovidone 200g, dextran 200g, sodium lauryl sulfate 50g, micronized silica gel 10g;

[0084] T3. Preparation of medicinal material extract dry paste powder: take Shouwu vine, add 3 times the amount of 70% ethanol soluti...

Example Embodiment

[0089] Example 2

[0090] A preparation method of dispersible tablets prepared from a traditional Chinese medicine preparation for treating dizziness, palpitations, insomnia and forgetfulness, includes the following steps:

[0091] T1. Take the following components: hydroxypropyl methyl cellulose, pregelatinized starch, crospovidone, sodium carboxymethyl starch, sodium lauryl sulfate, micronized silica gel, crushed through a 100 mesh sieve, and set aside ;

[0092] T2. Weigh the components according to the following parts by weight: Agrimonia 1200g, Eclipta prostrata 800g, Copris spatholobi 800g, Rehmannia glutinosa 800g, Rehmannia glutinosa 800g, Albizia julibrissin 800g, Shouwu vine 750g, Sodium alginate 500g, Hypromellose Base cellulose 200g, calcium sulfate 400g, crospovidone 300g, dextran 400g, sodium lauryl sulfate 15g, micronized silica gel 3g;

[0093] T3. Preparation of dry powder of medicinal material extract: Take Shouwu vine, add 5 times the amount of 70% ethanol solution...

Example Embodiment

[0098] Example 3

[0099] A preparation method of dispersible tablets prepared from a traditional Chinese medicine preparation for treating dizziness, palpitations, insomnia and forgetfulness, includes the following steps:

[0100] T1. Take the following components: hydroxypropyl methyl cellulose, pregelatinized starch, crospovidone, sodium carboxymethyl starch, sodium lauryl sulfate, micronized silica gel, crushed through a 100 mesh sieve, and set aside ;

[0101] T2. Weigh the components according to the following parts by weight: Agrimonia vulgaris 1000g, Eclipta prostrata 600g, Caulis spatholobi 600g, Rehmannia glutinosa 600g, Rehmannia glutinosa 600g, Albizia julibrissin 600g, Shouwu vine 600g, sodium alginate 400g, hypromellose 150g base cellulose, 300g calcium sulfate, 250g crospovidone, 300g dextran, 10g sodium lauryl sulfate, 2g micronized silica gel;

[0102] T3. Preparation of dry powder of medicinal material extract: Take Shouwu vine, add 4 times the amount of 70% ethanol...

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Abstract

The invention discloses a traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and a preparation method of the traditional Chinese medicine preparation. The preparation is prepared from the following components in parts by weight: 80-120 parts of hairyvein agrimony, 40-80 parts of eclipta, 40-80 parts of caulis spatholobi, 40-80 parts of radix rehmanniae praeparata, 40-80 parts of radix rehmanniae, 40-80 parts of cortex albiziae, 45-75 parts of vine multiflower knotweed, 30-50 parts of sodium alginate, 10-20 parts of hydroxypropyl methyl cellulose, 20-40 parts of calcium sulfate, 20-30 parts of crosslinking polyvingypyrrolidone, 20-40 parts of glucan, 5-15 parts of sodium dodecyl sulfate and 1-3 parts of aerosil. The preparation is a dispersed tablet, and the preparation method comprises the steps of preparing dry paste powder from medicinal materials through extraction; preparing a clathrate compound from the dry paste powder; and further preparing the dispersed table from the clathrate compound. The product is capable of obviously improving the solubleness of an indissolvable drug in the medicinal material extract dry paste powder, shortening the disintegration time limit and improving the bioavailability. The preparation method is simple in process, low in production cost and low in energy consumption, and industrial production is easy to implement.

Description

technical field [0001] The invention belongs to the field of medicines, and relates to a medicine and a preparation method thereof, in particular to a preparation method of a traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and amnesia. Background technique [0002] Yangxue Anshen Tablets are recorded in the sixth volume of the Ministry of Health’s Drug Standards for Traditional Chinese Medicine Prescriptions, the standard number is WS3-B-1199-92, and the prescription is: Agrimony 100g, Eclipta 60g, Millipeda 60g, Rehmannia glutinosa 60g , Rehmannia glutinosa 60g, Albizia juniper peel 60g, Shouwu vine 60g, made into 100 tablets, which are sugar-coated tablets, and the specifications are: the weight of the base tablet is about 0.25g (equivalent to 1.1g of total medicinal materials). It has the effect of nourishing yin and nourishing blood, and is clinically used to treat yin deficiency and blood deficiency, dizziness, palpitations, insomn...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/20A61K47/36A61K47/38A61K47/32A61K47/20A61K47/04A61K47/69A61K47/61A61P1/08A61P9/06A61P25/20A61P25/28
CPCA61K9/2009A61K9/2013A61K9/2027A61K9/2054A61K9/2059A61K36/28A61K36/48A61K36/486A61K36/704A61K36/73A61K36/804A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 黄大权邓春霞唐新
Owner 广西大海阳光药业有限公司
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