Traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and preparation method of traditional Chinese medicine preparation

Abstract

The invention discloses a traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and forgetfulness and a preparation method of the traditional Chinese medicine preparation. The preparation is prepared from the following components in parts by weight: 80-120 parts of hairyvein agrimony, 40-80 parts of eclipta, 40-80 parts of caulis spatholobi, 40-80 parts of radix rehmanniae praeparata, 40-80 parts of radix rehmanniae, 40-80 parts of cortex albiziae, 45-75 parts of vine multiflower knotweed, 30-50 parts of sodium alginate, 10-20 parts of hydroxypropyl methyl cellulose, 20-40 parts of calcium sulfate, 20-30 parts of crosslinking polyvingypyrrolidone, 20-40 parts of glucan, 5-15 parts of sodium dodecyl sulfate and 1-3 parts of aerosil. The preparation is a dispersed tablet, and the preparation method comprises the steps of preparing dry paste powder from medicinal materials through extraction; preparing a clathrate compound from the dry paste powder; and further preparing the dispersed table from the clathrate compound. The product is capable of obviously improving the solubleness of an indissolvable drug in the medicinal material extract dry paste powder, shortening the disintegration time limit and improving the bioavailability. The preparation method is simple in process, low in production cost and low in energy consumption, and industrial production is easy to implement.

Description

technical field [0001] The invention belongs to the field of medicines, and relates to a medicine and a preparation method thereof, in particular to a preparation method of a traditional Chinese medicine preparation for treating dizziness, palpitation, insomnia and amnesia. Background technique [0002] Yangxue Anshen Tablets are recorded in the sixth volume of the Ministry of Health’s Drug Standards for Traditional Chinese Medicine Prescriptions, the standard number is WS3-B-1199-92, and the prescription is: Agrimony 100g, Eclipta 60g, Millipeda 60g, Rehmannia glutinosa 60g , Rehmannia glutinosa 60g, Albizia juniper peel 60g, Shouwu vine 60g, made into 100 tablets, which are sugar-coated tablets, and the specifications are: the weight of the base tablet is about 0.25g (equivalent to 1.1g of total medicinal materials). It has the effect of nourishing yin and nourishing blood, and is clinically used to treat yin deficiency and blood deficiency, dizziness, palpitations, insomn...

AI Technical Summary

Problems solved by technology

The extraction process of the patent "a traditional Chinese medicine preparation with nourishing blood and calming nerves and its preparation method" (application number 200510003181.4) is as follows: the medicinal materials are extracted with water, concentrated, and then subjected to alcohol precipitation twice to remove impurities. Alcohol removed impurities twice, but the Radix Polygoni Multiflori medicinal material was only extracted with water, and the active ingredients were not extracted completely

None of the above extraction methods can meet the requirement that the impurities in the extract of traditional Chinese medicine should be as little as possible during the preparation of dispersible tablets, so as to ensure the content of active ingredients in the preparation and the requirements of drug efficacy.

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