Puncturing probe and imaging system and method applying same

Abstract

Provided are a puncturing probe and an imaging system and method applying the same. The puncturing probe includes at least one layer of needle tubes and micro probe heads, partial side walls of the needle tubes in the outer layer are of transparent structures, and the probe heads are integrated in an arbitrary layer of the needle tubes; the puncturing probe further comprises single mode optical fibers used for transmitting detection light beams and micro mirrors, wherein the single mode optical fibers and the micro mirrors are arrayed successively along an optical axis, each micro mirror is of an MEMS structure, can be driven to rotate in the vertical surface of the optical axis by the external and is used for reflecting the detection light beams to make the detection light beams transmit from the transparent structures to a to-be-detected tissue area; the micro mirrors are further used for receiving and reflecting light beams which carry tissue pathology information and are reflected by the to-be-detected tissue area, and then transmitting the light beams to external detection equipment for detecting the tissue pathology information. Thus, sampling only needs to be conducted in a probable lesion area, and therefore sampling frequency of living tissues can be effectively reduced, and meanwhile, the risk of complication is decreased, and the puncturing probe and the imaging system and method applying the same can be applied to real-time cancer detection conducted on a substantive deep organ.

Description

technical field [0001] The invention belongs to the field of optical imaging, and more specifically relates to a puncture probe and an imaging system and method using the same. Background technique [0002] Prostate cancer is the second most common cancer in men worldwide. In the past 20 years, the incidence of prostate cancer in my country has risen sharply, with an average annual growth rate of 12.07%, ranking sixth among male malignant tumors. Prostate cancer has an uneven distribution in the prostate, so prostate biopsy is considered the "gold standard" for prostate cancer diagnosis. Precisely sampled histological examination is a necessary condition for early diagnosis, early treatment and determination of cancer staging of prostate cancer. Currently, the standard diagnostic method of prostate cancer needle biopsy is: under the guidance of rectal ultrasound, transperineal and rectal puncture biopsy (Transrectal ultrasound guided biopsy, TRUS) histological sampling ana...

AI Technical Summary

Problems solved by technology

[0003] At present, the shortcomings of TRUS technology are: (1) the randomness of the sampling puncture point, resulting in an accuracy rate (true positive rate) of only 27-43%; (2) transrectal ultrasound is difficult to identify the tumor area on the image, Especially early lesions, so the randomness is strong; (3) If the number of puncture needles is small, false negatives will increase; if the number of puncture needles is too large, it will cause excessive pain to the patient, and 60-79% of the patients are accompanied by hematuria, Complications of blood semen, bloody stool, or bacterial infection, severe cases can cause massive bleeding

However, the cost of the procedure is substantially higher than that of TRUS

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