Pharmaceutical composition for treating burns and scalds, its preparation method and application

Abstract

The invention provides a pharmaceutical composition for treating burns and scalds as well as a preparation method and application thereof. The pharmaceutical composition is prepared from an effectivecomponent a and an effective component b, <0}{0><}0{>wherein the component a has the effects of clearing away heat and toxic materials as well as diminishing inflammation and relieving pain and is prepared from the following raw materials: 10-40 parts of giant knotweed rhizome, 5-35 parts of dandelion herb, 5-35 parts of lithospermum herb and 1-20 parts of borneol; <0}{0><}0{>and the component b has the effects of promoting blood circulation and removing blood stasis as well as removing necrotic tissue and promoting tissue regeneration and is prepared from the following raw materials: 10-40 parts of radix et rhizoma rhei, 10-40 parts of garden burnet root, 1-20 parts of radix codonopsis, 1-20 parts of radix astragali and 50-200 parts of egg white. <0}{0><}0{>The pharmaceutical compositionhas the advantages that medicines are respectively applied according to different effects of the traditional Chinese medicines, so that synergetic effects of the Chinese traditional medicine components can be fully exerted; compared with single drug prescription administration, the pharmaceutical composition has more obvious and stable curative effects; <0}{0><}0{>the pharmaceutical composition ismainly used for treating diseases caused by red, swollen, hot and painful wounds in preliminary and intermediate stages of burns and scalds and obvious exudation, reducing wound infection, accelerating wound healing and effectively reducing formation of ulcers at burn and scald parts, and is low in cost and free of toxic or side effect; <0}{0><}0{>and the preparation method of the pharmaceuticalcomposition is simple and feasible, all parameters are controllable, and large-scale production is facilitated.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and relates to a traditional Chinese medicine composition for treating burns and scalds, in particular to a medicinal composition for treating burns and scalds, a preparation method and application thereof. Background technique [0002] The records of water and fire burns in ancient medical literature first appeared in the "Wuwei Han Dynasty Medical Bamboo Slips", which is called "Soup and Fire Jelly". The cause of the disease is caused by the internal invasion of heat and toxin. Modern TCM theory thinks that burns and scalds are caused by heat, and there is toxicity in addition to heat, and its etiological mechanism is still heat toxicity. Burns in production and life are not only caused by water and fire, but also chemical burns and radiation burns often occur. [0003] The classification of burns and scalds adopts the three-degree four-point method. 1st degree burns only...

AI Technical Summary

Problems solved by technology

The existing traditional Chinese medicine preparations (such as MEBO) cannot effectively clean and protect the wound when they exert their medicinal effects, and their antibacterial effect is relatively weak. In clinical practice, they mostly rely on the combination of antibiotics to achieve corresponding antibacterial effects. Secondly, the compatibility of traditional Chinese medicine is a relatively complicated issue. The existing traditional Chinese medicine preparations for the treatment of burns and scalds contain at least a dozen or more than a hundred kinds of ingredients. Due to the complexity of the formula, neutralization, Precipitation, complexation, chelation and other chemical changes will reduce the curative effect or cause the drug effect to be lost, and even cause adverse reactions such as toxic reactions and harm to patients, affecting the absorption and efficacy of drugs

[0005] In addition, unlike thermal burns, the severity of chemical and radiation burns depends not only on the contact time with the skin, but also on the physical and chemical properties, injury mechanism and concentration of chemical substances; the mechanism of action includes oxidation, reduction, Corrosion, dehydration, etc., showing the characteristics of local progressive damage, and the burn area and degree are not easy to determine in the early stage

Existing burn preparations cannot effectively protect stasis zone tissue, achieve the purpose of controlling wound development and inhibiting scar hyperplasia

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