Preparation method for injection for treating diabetic wounds and product thereof

A technology of diabetes and injection, which is applied in the field of medicine, can solve the problems of weakened activity, weakened therapeutic effect, poor healing effect of diabetic refractory wounds, etc., and achieve the effect of enhanced effect
CN107929323AActive Publication Date: 2018-04-20THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV
Publication Date
2018-04-20

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Abstract

The invention discloses a preparation method for an injection for treating diabetic wounds and a product thereof. The preparation method comprises the following steps: (1) a solution which contains mesenchymal stem cells is prepared; (2) a mixed solution of type I collagen solution and laminin is prepared; (3) the mixed solution and the solution containing the mesenchymal stem cells are mixed andsufficiently and uniformly dispersed, and thereby the injection for treating diabetic wounds is obtained. According to the invention, the type I collagen and the laminin are mainly utilized to wrap the mesenchymal stem cells, the activity of the mesenchymal stem cells is protected, and thereby the problem that the therapeutic effect is weakened as time goes by in the process of treatment is avoided; moreover, the type I collagen and the laminin can cooperate with the mesenchymal stem cells, and thereby the therapeutic effect is further enhanced.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of an injection for treating diabetic wounds and a product thereof. Background technique

[0002] Wound healing is a complex biological process. It is a complex process in which inflammatory cells, repair cells, extracellular matrix, cytokines and other factors participate in and are highly coordinated and mutually regulated. The skin of diabetic patients is vulnerable to damage. After the damage, it often recurs and persists, forming stubborn and difficult-to-heal ulcers. Glycosylation, causing abnormal function of vascular endothelium and impaired response; abnormal function of macrophages, prolonged and unbalanced inflammatory response; lack or damage of growth factors, reduction of gelatin tissue, disorder of epidermal barrier function, and reduction of granulation tissue, etc. , resulting in ulcers that are difficult to heal. With the impr...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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