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Traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia and preparation method of traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation for preventing and treating hypoxia-induced insomnia, can solve problems such as aggravating hypoxia, dyspnea, etc., achieve accelerated release, avoid side effects, and have high safety Effect

Inactive Publication Date: 2018-06-05
SICHUAN JISHENG BIOPHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] If the patient injects or takes sedative drugs such as chlorpromazine and diazepam (stable) to treat insomnia caused by high altitude hypoxic conditions, since these drugs have the side effect of inhibiting breathing, it is very easy to cause breathing problems due to inaccurate dose control. Difficulty and aggravation of hypoxia, and this kind of sedative drugs also have other adverse reactions, such as eye complications, orthostatic hypotension, constipation, etc.

Method used

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  • Traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia and preparation method of traditional Chinese medicine composition

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Embodiment 1

[0041] A traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia. The traditional Chinese medicine composition includes the following active components in parts by mass: 8 parts of theanine, 3 parts of hawthorn leaf extract, 1 part of Suanzaoren extract, bergamot Extract 1 part.

[0042] Further, the traditional Chinese medicine composition also includes the following excipients in parts by mass: 1 part of silicon dioxide, 5 parts of microcrystalline cellulose, 4 parts of calcium lactate, 2 parts of calcium carbonate, 0.01 part of sucralose, magnesium stearate 0.1 part.

[0043] A method for preparing a traditional Chinese medicine composition for preventing and treating hypoxia-induced insomnia, the steps are as follows:

[0044] 1) Weigh theanine, hawthorn leaf extract, jujube seed extract, bergamot extract and silicon dioxide, put them into a mixer and dry mix for 10 minutes;

[0045]2) Weighing sucralose, microcrystalline cellulose...

Embodiment 2

[0054] A traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia, said Chinese medicine composition comprising the following active components in parts by mass: 8 parts of theanine, 5 parts of hawthorn leaf extract, 2 parts of jujube seed extract, bergamot Extract 2 parts.

[0055] Further, the traditional Chinese medicine composition also includes the following excipients in parts by mass: 2 parts of silicon dioxide, 8 parts of microcrystalline cellulose, 7 parts of calcium lactate, 4 parts of calcium carbonate, 0.05 parts of sucralose, magnesium stearate 0.5 servings.

[0056] A method for preparing a traditional Chinese medicine composition for preventing and treating hypoxia-induced insomnia, the steps are as follows:

[0057] 1) Weigh theanine, hawthorn leaf extract, jujube seed extract, bergamot extract and silicon dioxide, put them into a mixer and dry mix for 10 minutes;

[0058] 2) Weighing sucralose, microcrystalline cellulos...

Embodiment 3

[0067] A traditional Chinese medicine composition for preventing and treating hypoxia-induced insomnia, said Chinese medicine composition comprising the following active components in parts by mass: 8 parts of theanine, 4 parts of hawthorn leaf extract, 1 part of Semen jujube extract, bergamot Extract 1 part.

[0068] Further, the traditional Chinese medicine composition also includes the following excipients in parts by mass: 1.5 parts of silicon dioxide, 6 parts of microcrystalline cellulose, 6 parts of calcium lactate, 3 parts of calcium carbonate, 0.02 parts of sucralose, magnesium stearate 0.3 parts.

[0069] A method for preparing a traditional Chinese medicine composition for preventing and treating hypoxia-induced insomnia, the steps are as follows:

[0070] 1) Weigh theanine, hawthorn leaf extract, jujube seed extract, bergamot extract and silicon dioxide, put them into a mixer and dry mix for 10 minutes;

[0071] 2) Weighing sucralose, microcrystalline cellulose, c...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia and a preparation method of the traditional Chinese medicine composition, relates to the technical field of traditional Chinese medicines and aims at preventing and treating the insomnia caused by the hypoxia. The traditional Chinese medicine composition is prepared from the following active components in parts by mass: 8 parts of theanine, 3-5 parts of a hawthorn leaf extract, 1-2 parts of a semen ziziphi spinosae extract and 1-2 parts of a fructus citri sarcodactylis extract. The preparation method comprises the following steps of 1) weighing the theanine, the hawthorn leaf extract, the semen ziziphi spinosae extract, the fructus citri sarcodactylis extract and silicon dioxide, and performing dry mixing; 2) weighing sucralose, microcrystalline cellulose, calcium carbonate and calcium lactate, and performing dry mixing; 3) uniformly spraying 70 percent ethanol, andperforming stirring to prepare wet particles; 4) performing drying treatment; 5) performing particle separating treatment on dry particles in the step 4); 6) adding magnesium stearate in the particles in the step 5) for mixing; and 7) performing inspection, tabletting, tablet screening and coating on the particles in the step 6) to obtain the traditional Chinese medicine composition. The traditional Chinese medicine composition provided by the invention has very good effects of tranquilizing, soothing nerves and assisting sleeping on the insomnia caused by the hypoxia.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for preventing and treating insomnia caused by hypoxia and a preparation method thereof. Background technique [0002] Altitude sickness is a variety of discomforts caused by the human body rapidly entering the plateau above 3,000 meters above sea level and being exposed to a low-pressure and hypoxic environment. It is a common disease unique to plateau areas. Common symptoms include headache, insomnia, loss of appetite, tiredness, and difficulty breathing. Among them, insomnia refers to poor sleep. Although the sleep time is long, the sleep quality is poor, easy to wake up, and always in a light sleep state. [0003] If the patient injects or takes sedative drugs such as chlorpromazine and diazepam (stable) to treat insomnia caused by high altitude hypoxic conditions, since these drugs have the side effect of inhi...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/28A61K47/04A61K47/38A61K47/12A61K47/02A61K47/26A61P25/20A61P39/00A61K31/198
CPCA61K9/2009A61K9/2013A61K9/2054A61K31/198A61K36/725A61K36/734A61K36/752A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 杨帆费东田安全
Owner SICHUAN JISHENG BIOPHARM CO LTD