Pediatric paracetamol, artificial cow-bezoar and chlorphenamine maleate granules and preparation method thereof
A technology for pediatric paracetamol and composition, which is applied to the field of pediatric paracetamol xanthamine composition granules and their preparation fields, can solve the problems of unstable product quality, inconvenience to take, poor stability and the like, and achieves improved granule solubility and improved stability. The effect of stability and good stability
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0042] A kind of Pediatric paracetamol xanthramine composition granule, it is made by following method:
[0043] The raw materials for configuring active ingredients include: 25 parts by weight of acetaminophen, 1 part by weight of artificial bezoar, 0.095 parts by weight of chlorpheniramine maleate, 779 parts by weight of sucrose, and 1.2 parts by weight of essence.
[0044] Add the sucrose into the pulverizer, grind it into fine powder, pass through an 80-mesh sieve, and divide it into the first part of sucrose and the second part of sucrose. Mix acetaminophen, artificial bezoar, chlorpheniramine maleate and the first part of sucrose to obtain a mixture. Add the second part of the sucrose aqueous solution to the mixture at 3000Pa and 35°C to make soft materials. After granulation, first sieve with a 60-mesh stainless steel screen to recover the material on the sieve, and then pass the obtained under-sieve material through a 10-mesh Sieve through a stainless steel screen to ...
Embodiment 2
[0047] A kind of Pediatric paracetamol xanthramine composition granule, it is made by following method:
[0048] The raw materials for configuring active ingredients include: 25 parts by weight of acetaminophen, 1 part by weight of artificial bezoar, 0.095 parts by weight of chlorpheniramine maleate, 779 parts by weight of sucrose, and 1.2 parts by weight of essence.
[0049] Add the sucrose into the pulverizer, grind it into fine powder, pass through an 80-mesh sieve, and divide it into the first part of sucrose and the second part of sucrose. After mixing acetaminophen, artificial bezoar, and chlorpheniramine maleate, the first part of sucrose was added in 5 times under the condition of 45 r / min to obtain a mixture. Add the second part of the sucrose aqueous solution to the mixture at 3000Pa and 35°C to make soft materials. After granulation, first sieve with a 60-mesh stainless steel screen to recover the material on the sieve, and then pass the obtained under-sieve materia...
Embodiment 3
[0052] A kind of Pediatric paracetamol xanthramine composition granule, it is made by following method:
[0053] Raw materials for configuring active ingredients, which include: 25 parts by weight of acetaminophen, 1 part by weight of artificial bezoar, 0.095 parts by weight of chlorpheniramine maleate, 779 parts by weight of sucrose, and 0.03 parts by weight of a water-soluble shell polysaccharide, and the essence of 1.2 parts by weight. Add the sucrose into the pulverizer, grind it into fine powder, pass through an 80-mesh sieve, and divide it into the first part of sucrose and the second part of sucrose. Mix acetaminophen, artificial bezoar, chlorpheniramine maleate and the first part of sucrose to obtain a mixture. Add the second part of the sucrose aqueous solution to the mixture at 3000Pa and 35°C to make soft materials. After granulation, first sieve with a 60-mesh stainless steel screen to recover the material on the sieve, and then pass the obtained under-sieve mater...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com