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Ointment for treating knee osteoarthritis

A technology for knee osteoarthritis and ointment, applied in the field of ointment for treating knee osteoarthritis, can solve the problems of unsatisfactory use and curative effect, and achieve the effects of abundant raw materials, scientific and reasonable formulation, and easy production

Inactive Publication Date: 2018-07-13
史兰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are a variety of traditional Chinese medicines for the treatment of knee osteoarthritis, their use and efficacy are not satisfactory due to various reasons. Therefore, improvement and innovation in the treatment of knee osteoarthritis drugs is imperative

Method used

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  • Ointment for treating knee osteoarthritis
  • Ointment for treating knee osteoarthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1: An ointment for treating knee osteoarthritis, made of the following raw materials in percentage by weight: Aconitum aconitum 0.68-0.74%, Herba Asarum 1.04-1.10%, Panworm 1.04-1.10%, Garcinia cambogia 1.40 -1.46%, Hedyotis 1.40-1.46%, Scutellaria barbata 1.40-1.46%, Papaya 1.40-1.46%, Sichuan Pepper 1.40-1.46%, Dried Ginger 1.40-1.46%, Zanthoxylum bungeanum 1.40-1.46%, Scutellaria 1.40-1.46%, Qingfengteng 1.40-1.46%, Sappan 1.40-1.46%, Chuan Achyranthes 2.2-2.8%, Centipede 0.33-0.39%, Sodium polyacrylate 4.5-5.5%, Cross-linked polyacrylate 2.5-3.5% %, aluminum glycinate 0.07-0.13%, sodium hydroxide 0.05-0.11%, glacial acetic acid 0.17-0.23%, citric acid 0.07-0.13%, pentanediol 1.7-2.3%, hexanediol 1.7-2.3%, glycerin 9- 11%, 0.7-1.3% p-hydroxyacetophenone and 53-59% water; wherein, the above-mentioned glacial acetic acid, citric acid, p-hydroxyacetophenone, and hexanediol are added to water, and stirred evenly to obtain phase A; Add the above-mentioned sodi...

Embodiment 2

[0012] Embodiment 2: An ointment for treating knee osteoarthritis, made of the following raw materials in percentage by weight: Aconitum aconitum 0.71%, Herba Asarum 1.07%, Panworm 1.07%, Garcinia cambogia 1.43%, and Hedyotis baicalensis 1.43%, Banzhilian 1.43%, Papaya 1.43%, Sichuan Pepper 1.43%, Dried Ginger 1.43%, Zanthoxylum bungeanum 1.43%, Speranium 1.43%, Qingfengteng 1.43%, Sappan 1.43%, Sichuan Achyranthes bidentata 2.50%, Centipede 0.36%, Sodium Polyacrylate 5%, Cross-linked Polyacrylate 3%, Aluminum Glycinate 0.1%, Sodium Hydroxide 0.08%, Glacial Acetic Acid 0.2%, Citric Acid 0.1%, Pentylene Glycol 2%, Hexylene Glycol 2% , glycerin 10%, p-hydroxyacetophenone 1% and water 56.51%; Wherein, the above-mentioned glacial acetic acid, citric acid, p-hydroxyacetophenone, hexanediol are added to water, stir to obtain A phase; Sodium polyacrylate, cross-linked polyacrylate, aluminum glycinate, sodium hydroxide are added to pentylene glycol and glycerin, and stirred evenly to ...

Embodiment 3

[0013] Embodiment 3: a kind of ointment for the treatment of knee osteoarthritis of the present invention is made of the following raw materials in percentage by weight: Aconitum aconitum 0.76%, Asarum 1.12%. Tongue grass 1.48%, Scutellaria barbata 1.48%, Papaya 1.48%, Sichuan pepper 1.48%, Dried ginger 1.48%, Zanthoxylum bungeanum 1.48%, Sperancus 1.48%, Qingfengteng 1.48%, Sappan 1.48%, Chuan Achyranthes bidentata 3.0 %, centipede 0.41%, sodium polyacrylate 6%, cross-linked polyacrylate 4%, aluminum glycinate 0.15%, sodium hydroxide 0.13%, glacial acetic acid 0.25%, citric acid 0.15%, pentylene glycol 2.5%, hexanediol 2.5%, 12% glycerin, 1.5% p-hydroxyacetophenone, and 61% water; wherein, the above-mentioned glacial acetic acid, citric acid, p-hydroxyacetophenone, and hexanediol were added to water, and stirred evenly to obtain phase A; Add the above-mentioned sodium polyacrylate, cross-linked polyacrylate, aluminum glycinate, and sodium hydroxide to pentylene glycol and gly...

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Abstract

The invention aims to provide an ointment for treating knee osteoarthritis. The ointment is prepared from the following raw materials: processed kusnezoff monkshood root, asarum herb, scorpio, resinagarciniae, spreading hedyotis herb, barbed skullcap herb, common flowering quince fruit, fructus zanthoxyli, dried ginger, pricklyash peel, tuberculate speranskia herb, caulis sinomenii, sappan wood,medicinal cyathula root, centipede, sodium polyacrylate, crosslinked polyacrylate, aluminum glycinate, sodium hydroxide, glacial acetic acid, citric acid, pentanediol, hexanediol, glycerol, p-hydroxyacetophenone, and water. The ointment provided by the invention has the advantages of scientific and reasonable formula, rich raw materials, simple preparation method, easy production, convenient administration, safety, reliability, exact curative effect, good effect and no side effect, is effectively used for treating knee osteoarthritis, is an innovation in medicines for treating knee osteoarthritis, and has good economic and social benefits.

Description

technical field [0001] The invention relates to traditional Chinese medicine, in particular to an ointment for treating knee osteoarthritis. Background technique [0002] Osteoarthritis (OA) is a chronic, degenerative arthritis disease characterized by degeneration and destruction of articular cartilage, hyperplasia of joint margins, subchondral bone, and inflammatory changes of intra-articular tissues. Knee osteoarthritis (KOA) is the most common clinically due to weight bearing, and it is more common in elderly women. Risk factors include obesity, knee trauma, and meniscectomy. Epidemiology shows that in my country its incidence rate is 50% over the age of 60 and 80% over the age of 75. [0003] Modern medicine believes that KOA is based on the degenerative changes of articular cartilage. Under the joint action of mechanics and biology, the degradation and synthesis of chondrocytes, extracellular matrix and subchondral bone are out of balance, especially in the elderly. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/06A61P19/08A61P19/02A61K35/646A61K35/648
CPCA61K9/06A61K35/646A61K35/648A61K36/185A61K36/21A61K36/268A61K36/38A61K36/47A61K36/48A61K36/539A61K36/59A61K36/714A61K36/732A61K36/748A61K36/758A61K36/9068A61K47/32A61K2300/00
Inventor 史兰史栋梁
Owner 史兰
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