Medicine for external use for phlegm dampness stasis heat alopecia seborrheica

A technology for seborrheic alopecia and external use of drugs, which can be used in drug combinations, pharmaceutical formulations, plant raw materials, etc., and can solve problems such as poor efficacy and dull pain.

Active Publication Date: 2018-07-20
霸王(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, western medicine uses hormone drugs, but the curative effect is not good,...

Method used

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  • Medicine for external use for phlegm dampness stasis heat alopecia seborrheica
  • Medicine for external use for phlegm dampness stasis heat alopecia seborrheica
  • Medicine for external use for phlegm dampness stasis heat alopecia seborrheica

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Example 1 (tincture)

[0014] Take 10g of ginger, 12g of butterbur, 12g of Digupi, 15g of plantain, 15g of Phellodendron 15g, 15g of white mustard seed, and 21g of polygala, add 8 times the amount of water, soak for 30 minutes, reflux extraction for 1.5 hours, extract twice, filter, Combine the filtrates, concentrate to 100ml, add 100ml of absolute ethanol, let stand overnight, and filter. Add 100 g of propylene glycol to the filtrate and mix uniformly to obtain a tincture.

Embodiment 2

[0015] Embodiment 2 (lotion)

[0016] Take 8g of ginger, 10g of butterbur, 13g of Digupi, 15g of plantain, 15g of Cortex Phellodendri, 18g of white mustard seed, and 21g of polygala, add 12 times the amount of water, soak for 30 minutes, reflux extraction for 1.5 hours, extract twice, filter, Combine the filtrates, concentrate to 100ml, and filter to obtain lotion.

Embodiment 3

[0017] Embodiment 3 (cream)

[0018] Take 12g of ginger, 10g of butterbur, 10g of Digupi, 10g of plantain, 18g of Phellodendron cortex, 12g of white mustard seed, and 28g of polygala, add 12 times the amount of water, soak for 30min, heat and reflux for extraction for 2 hours, and keep slightly boiling. Filter at room temperature, steam in a water bath at 100°C to form a thick paste.

[0019] Water phase: Take 8.0g of the above thick paste, add 6.0g of azone, 20.0g of glycerin, 7.0g of propylene glycol, 1.5ml of Tween-60 and 0.5ml of K-12, and then add distilled water to 73.5ml.

[0020] Oil phase: Add 6.5g of stearyl alcohol, 6.0g of white oil, 4.5g of glyceryl monostearate, 2.5g of isopropyl palmitate, 7.0g of Danthrene, 0.15ml of methylparaben, and propylparaben Ester 0.05ml and CY 0.05ml.

[0021] Put the water phase and the oil phase in a container respectively, heat the water phase to 85-95°C, heat the oil phase until it melts, and slowly add the oil phase to the water...

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PUM

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Abstract

The invention relates to a medicine for external use for phlegm dampness stasis heat alopecia seborrheica. The medicine comprises active ingredients and medically acceptable adjuvant, wherein the active ingredients are composed of aqueous extracts of following crude drug substances consisting of, by weight, 5-15% of fresh ginger, 5-20% of butterbur, 10-20% of cortex lycii radicis, 10-20% of plantain, 12-20% of golden cypress, 12-25% of semen brassicae and 10-30% of polygala root. The composition for external use of traditional Chinese medicine has the effects of clearing away heat and detoxifying, clearing away heat and drying dampness, dissipating phlegm for resuscitation, dispersing blood stasis and swelling and the like, and has remarkable effects on the phlegm dampness stasis heat alopecia seborrheica.

Description

technical field [0001] The invention relates to a medicinal preparation containing an undetermined structure from plants, which can prevent and treat seborrheic alopecia of phlegm-dampness-stasis-heat type. Background technique [0002] Modern scientific research thinks that seborrheic alopecia is also called androgenetic alopecia, male pattern alopecia. Occurs in young males, has a genetic susceptibility and is also affected by androgen. Modern medicine believes that seborrheic alopecia is the result of a combination of many factors, including genetics, immune regulation, and changes in hormones, cytokines, growth factors, neuropeptides, and neurotrophic factors in the body. According to reports, more than 70% of the patients with seborrheic alopecia have obvious family medical history. Studies in recent years have shown that AGA belongs to autosomal dominant genetic inheritance, and people with genetic susceptibility are prone to hair loss. There are six treatment method...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P17/14
CPCA61K36/28A61K36/31A61K36/68A61K36/69A61K36/756A61K36/815A61K36/9068A61K2300/00
Inventor 陈启源张榕文刘强朱红霞
Owner 霸王(广州)有限公司
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