Traditional Chinese medicine hemsley rockvine root processing method capable of keeping pharmaceutical-effect active ingredient

A technology of active ingredients and processing methods, which is applied in the field of traditional Chinese medicine trefoil processing that retains medicinal active ingredients, can solve problems such as high cost, high production cost, and loss of medicinal active ingredients, so as to prevent loss or damage and ensure Speed ​​and effect, boost retention effect

Active Publication Date: 2018-08-03
安吉三叶青生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This process improves the retention of medicinal active ingredients to a certain extent by rationally configuring parameters such as time, temperature, and pressure of vacuum freezing. However, a large amount of medicinal active ingredients are still lost during the drying process.
In addition, the large investment and high energy consumption of vacuum freeze-drying equipment lead to high production costs and limit the application of the technology to a certain extent.
[0008] One of the common usages of the traditional Chinese medicine Clover is decocted with water, but in the process of decocting with water, a large amount of active ingredients are either lost due to evaporation, or destroyed due to high temperature, oxidation and other reasons. 3-5% of the medicinal active ingredients are decocted in water, and a large amount of medicinal active ingredients are wasted
Another method is to make oral preparations, but the most critical steps of pulverization and wall breaking in the preparation process need to be manually ground, which has poor wall breaking effect and high cost; and the drug effect may be caused by excessive local temperature during the grinding process. Active ingredient lost or destroyed

Method used

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  • Traditional Chinese medicine hemsley rockvine root processing method capable of keeping pharmaceutical-effect active ingredient
  • Traditional Chinese medicine hemsley rockvine root processing method capable of keeping pharmaceutical-effect active ingredient
  • Traditional Chinese medicine hemsley rockvine root processing method capable of keeping pharmaceutical-effect active ingredient

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Step 1: Select fresh clover root tubers and wash them with water;

[0048] Step 2: Preliminarily dry the washed Pseudomonas clover root at 65°C under a nitrogen atmosphere, remove the water remaining on the surface due to water washing, and take it out after cooling;

[0049] Step 3: Cut off the inferior part, and cut the remaining part into thin slices with a thickness of 2.5mm;

[0050] Step 4: Dry the Clover flakes at 65°C under a nitrogen atmosphere for 20 minutes for the first time, and take them out after cooling;

[0051] Step 5: placing the first dried Clover flakes in a dry refrigerator and refrigerating them to 5°C;

[0052] Step 6: freezing with liquid nitrogen, freezing the refrigerated Clover flakes to below minus 55°C within 15 minutes;

[0053] Step 7: Blow a dry mixed gas of argon and helium with a molar ratio of 1:1 at 55°C on the surface of the frozen Clover flakes at a gas flow rate of 1.4m / s, and further dry to contain The water content is 2.15%, ...

Embodiment 2

[0055] Step 1: Select fresh clover root tubers and wash them with water;

[0056] Step 2: Preliminarily dry the washed Clover root at 55°C under a nitrogen atmosphere, remove the water remaining on the surface due to water washing, and take it out after cooling;

[0057] Step 3: Cut off the inferior part, and cut the remaining part into thin slices with a thickness of 1.5mm;

[0058] Step 4: Dry the Clover flakes at 60°C under a nitrogen atmosphere for 15 minutes for the first time, and take them out after cooling;

[0059] Step 5: placing the Clover flakes after the initial drying in a dry refrigerator to refrigerate to 3°C;

[0060] Step 6: Vitrification ultrafast freezing is used to freeze the refrigerated Clover flakes to minus 125°C within 3 minutes;

[0061] Step 7: Blow a dry mixed gas of argon and helium at a molar ratio of 0.5:1 at 35°C on the surface of the frozen Clover flakes at a gas flow rate of 0.5m / s, and further dry until the surface contains The water cont...

Embodiment 3

[0063] Step 1: Select fresh clover root tubers and wash them with water;

[0064] Step 2: Preliminarily dry the washed Pseudomonas clover root at 75°C under a nitrogen atmosphere, remove the water remaining on the surface due to water washing, and take it out after cooling;

[0065] Step 3: Cut off the inferior part, and cut the remaining part into slices with a thickness of 3.5mm;

[0066] Step 4: Dry the Clover flakes at 70°C under a nitrogen atmosphere for 25 minutes for the first time, and take them out after cooling;

[0067] Step 5: placing the Clover flakes after the initial drying in a dry refrigerator to refrigerate to 7°C;

[0068] Step 6: Using gas turbo expansion refrigeration, freezing the refrigerated Clover flakes to minus 25°C within 35 minutes;

[0069] Step 7: Blow a dry mixed gas of argon and helium with a molar ratio of 2:1 at 65°C on the surface of the frozen Clover flakes at a gas flow rate of 2 m / s, and further dry to the water content It is 2.9%, and...

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Abstract

The invention discloses a traditional Chinese medicine hemsley rockvine root processing method capable of keeping a pharmaceutical-effect active ingredient. The traditional Chinese medicine hemsley rockvine root processing method comprises the following steps: selecting fresh hemsley rockvine roots and washing; preliminarily drying the washed hemsley rockvine roots at a temperature being 55-75 DEGC under a nitrogen-gas atmosphere, removing water left after washing on the surface, and taking out after cooling; cutting off bad parts, and cutting the residual parts into slices with thicknesses being 1.5-3.5 mm; primarily drying hemsley rockvine root slices at a temperature being 60-70 DEG C, preliminarily drying for 15-25 minutes under nitrogen-gas atmosphere, and taking out after cooling; putting the preliminarily dried hemsley rockvine root slices into a drying and refrigerating room to refrigerate to 3-7 DEG C; adopting a quick freezing technology for freezing the refrigerated hemsleyrockvine root slices to a temperature being -25 DEG C to -125 DEG C within 3-35 minutes, blowing dried non-oxidative gas to the surfaces of frozen hemsley rockvine root slices, and further drying until moisture content is 1.4-2.9%. The drying technology, the freeze-drying technology and the gas-flow drying technology are comprehensively applied, and the atmosphere, the temperature and the time are controlled in each step, so that the retention effect of the traditional Chinese medicine active ingredient is greatly improved in a drying process.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine processing, in particular to a processing method of traditional Chinese medicine trefoil that retains medicinal active ingredients. Background technique [0002] Clover is the root or whole plant of Cliff Cliff vine in the family Vitis genus, also known as golden thread hanging gourd, silk thread hanging golden bell, three-leaf flat rattan, stone mouse, small flat rattan, stone monkey, soil classics Pills, three-leaf pairs, one-grain beads, etc., are mainly produced in Jiangsu, Zhejiang, Jiangxi, Fujian, Taiwan, Guangdong, Guangxi, Hubei, Hunan and other places. Its medicinal records were first seen in "Compendium of Materia Medica", which is called "Sanyegan climbing vine, bitter, pungent, cool in nature, clearing heat and cooling blood, promoting blood circulation and expelling wind". Clover is recorded in "National Chinese Herbal Medicine Compilation", "Chinese Medicine Chronicles",...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61K125/00
CPCA61K36/87A61K2236/13A61K2236/15A61K2236/17
Inventor 李熙华方志财单雪峰陈静范仲华
Owner 安吉三叶青生物科技有限公司
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