Unlock instant, AI-driven research and patent intelligence for your innovation.

Antibacterial silver-loaded silicone rubber material and preparation method thereof

A silicone rubber and silver-carrying technology, which is applied in the field of biomedical materials, can solve the problems of inability to achieve antibacterial effect and limited quantity of antibacterial substances, and achieve the effects of stable immobilization, simple and easy method, and uniform size.

Inactive Publication Date: 2018-09-21
SOUTH CHINA UNIV OF TECH
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the amount of antibacterial substances loaded by swelling silica gel is very limited, and a good antibacterial effect cannot be achieved.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Antibacterial silver-loaded silicone rubber material and preparation method thereof
  • Antibacterial silver-loaded silicone rubber material and preparation method thereof
  • Antibacterial silver-loaded silicone rubber material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] (1) Divide 20×20mm 2 The silicone rubber (heat-vulcanized silicone rubber purchased from Guangdong Biaomei Silicon Fluorine New Material Co., Ltd.) was placed on the Xe 2 * Excimer vacuum ultraviolet lamp (radiation wavelength 172nm, radiation intensity 90mW / cm 2 ), irradiated for 180s to obtain surface-activated silicone rubber;

[0042] (2) Soak the surface-activated silicone rubber in an aqueous solution of dopamine with a concentration of 2g / L (the pH of the solution is 8), react for 20 hours at 50°C, take it out, rinse it with deionized water for 3 times, and dry it with nitrogen to obtain activated silicone rubber. Polydopamine-coated silicone rubber, marked Activated-SF-PDA;

[0043](3) Soak the non-surface-activated silicone rubber in an aqueous solution of dopamine with a concentration of 2g / L (the pH of the solution is 8), react at 50°C for 20h, take it out, rinse it with deionized water for 3 times, and dry it with nitrogen to obtain The silicone rubber (...

Embodiment 2

[0048] (1) Divide 20×20mm 2 The silicone rubber (the heat-vulcanized silicone rubber purchased from Guangdong Caiyan Co., Ltd.) is placed under a vacuum ultraviolet lamp (irradiation wavelength 167.7nm, irradiation intensity 70mW / cm 2 ), irradiated for 60s to obtain surface-activated silicone rubber;

[0049] (2) Soak the surface-activated silicone rubber in an aqueous solution of dopamine (pH 7) with a concentration of 20 g / L, react at room temperature for 48 hours in an oxygen atmosphere, take it out, rinse it with deionized water for 3 times, and dry it with nitrogen gas to obtain activation. Polydopamine-coated silicone rubber, marked Activated-SF-PDA;

[0050] (3) Soak the silicone rubber without surface activation treatment directly in the dopamine aqueous solution (pH 7) with a concentration of 20g / L, react at room temperature under an oxygen atmosphere for 48 hours, take it out, rinse it with deionized water three times, and blow it with nitrogen. Dry, obtain the sil...

Embodiment 3

[0054] (1) Divide 20×20mm 2 The silicone rubber (Dow Corning sylgard 184 room temperature vulcanized silicone rubber) was placed under a vacuum ultraviolet lamp (irradiation wavelength 124nm, radiation intensity specifically 30mW / cm 2 ), irradiated for 10s to obtain surface-activated silicone rubber;

[0055] (2) Soak the surface-activated silicone rubber in a dopamine solution with a concentration of 15g / L (the pH of the solution is 12), react for 1 hour at 5°C in an oxygen atmosphere, take it out, rinse it with deionized water for 3 times, and blow it with nitrogen. Dry, obtain the silicone rubber of surface coating polydopamine;

[0056] (3) configure the silver nitrate solution of 15g / L, slowly add ammoniacal liquor dropwise to the solution and become clear and transparent, obtain the silver ammonia solution; the silicon rubber of the surface coating polydopamine of step (2) is soaked in the silver ammonia solution, 5 After reacting at ℃ for 1 hour, take it out, rinse wi...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
wavelengthaaaaaaaaaa
concentrationaaaaaaaaaa
concentrationaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the technical field of biomedical materials, and discloses an antibacterial silver-loaded silicone rubber material and a preparation method thereof. The method comprises the steps that 1, ultraviolet radiation is adopted, surface activation is conducted on silicone rubber, and activated silicon rubber is obtained; 2, the surface of the activated silicon rubber is wrapped by polydopamine, and silicon rubber with the surface wrapped by polydopamine is obtained; 3, silver nanoparticles are immobilized on the surface of the silicon rubber with the surface wrapped by polydopamine, and the antibacterial silver-loaded silicone rubber material is obtained. Accordingly, the method is simple and easy to implement; meanwhile, the silicon rubber and polydopamine can generate chemical bonding or hydrogen-bond interaction, and the surface of the silicon rubber is wrapped by polydopamine uniformly, firmly and compactly; the silver nanoparticles are immobilized on the surfaceof the silicon rubber through a reduction method, and the silver nanoparticles have very stable immobilization property; in addition, the prepared antibacterial silver-loaded silicone rubber has the outstanding and everlasting antibacterial effect.

Description

technical field [0001] The invention belongs to the technical field of biomedical materials, and in particular relates to an antibacterial silver-loaded silicone rubber material with nano-silver particles deposited on the surface and a preparation method thereof. Background technique [0002] Due to its good chemical stability, non-toxicity, non-sensitization, good biocompatibility and good processing performance, silicone rubber has a wide range of applications in the field of biomedicine. Common medical silicone rubber products include catheters, Cosmetic restoration implants, medical dressings, etc. However, the internal polarity of silicone rubber molecules is low, resulting in low surface energy and strong surface hydrophobicity of silicone rubber, which makes it easy for bacteria to adhere to the surface of silicone rubber materials. For patients, bacterial adhesion can easily cause wound infection and even lead to more serious consequences. Therefore, it is necessary...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C08J7/04C08J3/28
CPCC08J3/28C08J7/0423C08J2383/04C08J2479/04
Inventor 吴叔青曹琴
Owner SOUTH CHINA UNIV OF TECH