Glass simulating sponge support and preparing method thereof

A technology of sponge and glass, which is applied in the field of medical stents, can solve the problems of limited applicability of Ni-Ti shape memory alloy stents, the size of the diseased part changes the size of the structure itself, and so on, so as to save treatment costs, relieve obstruction, and avoid extrusion Effect

Inactive Publication Date: 2018-10-02
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The present invention aims to solve the problem that the current alloy stent cannot change the size of the structure itse

Method used

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  • Glass simulating sponge support and preparing method thereof
  • Glass simulating sponge support and preparing method thereof
  • Glass simulating sponge support and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0039] Specific implementation mode one: combine Figure 1 to Figure 9 To describe this embodiment,

[0040] A kind of imitation glass sponge support, including bionic tissue engineering support 1 and ribs 2, described bionic tissue engineering support 1 is composed of a group of axial support meridians 5 and two sets of helically surrounded support base lines 4 with a through-hole The cylindrical wall of the hole 3, and the two groups of bracket baselines 4 are two-way circles (cross-connection will occur during the circle process), that is, the two groups of bracket baselines 4 are respectively circled clockwise and counterclockwise; at the same time, the brackets with the same direction There is a distance between the helices formed around the baseline 4, and the distance between the corresponding helixes intersected by the stent meridian 5 and the stent baseline 4 forms a through hole 3; the through hole 3 can be triangular, quadrilateral, pentagonal, hexagonal, Octagon, ...

specific Embodiment approach 2

[0047] The printing material described in this embodiment also contains medicine.

[0048] Other structures and materials are the same as those in Embodiment 1.

[0049] After shape-memory polycaprolactone, shape-memory polylactic acid, and shape-memory polyurethane are used as printing materials to print scaffolds and implant them in the body, since this printing material has the characteristics of degradation in the body, it is added to the printing material to treat the affected area. The corresponding drugs need to be added according to the actual situation of the affected area. Then as the stent degrades in the body, the drug in the stent is released and promotes endothelialization and tissue growth at the site. That is, the stent of the present invention can be loaded with drugs and implanted.

specific Embodiment approach 3

[0050] When one or more of shape-memory polycaprolactone, shape-memory polylactic acid, and shape-memory polyurethane is used as the printing material in this embodiment, a reinforcing material is added to the printing material, and the reinforcing material includes starch, cellulose, One or more of chitin, lignin, hyaluronic acid and alginic acid.

[0051] Other structures and materials are the same as those in Embodiment 1 or Embodiment 2.

[0052] The strength of the present invention is not only related to the structure of the imitation glass sponge, but also related to the printing material itself. The reinforcing material can not only increase the strength of the stent, but also help the corresponding printing material of the shape memory polymer to adjust the appropriate glass transition temperature, so that the stent can change shape and size according to the preset temperature in the human body.

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Abstract

The invention discloses a glass simulating sponge support and a preparing method thereof, and relates to a medical support and the preparing method thereof. The problem that the structural size of anexisting alloy support cannot be changed according to the size of an affected part and the problem that the applicability of a Ni-Ti shape memory alloy support is limited are solved. A bionic tissue engineering scaffold of the support is a cylinder wall with a through hole, wherein the cylinder wall is composed of an auxiliary support warp and two spirally-surrounding support base yarns, the two support base yarns are bidirectionally surrounding, and ribs are spirally arranged on the outer wall of the bionic tissue engineering scaffold. The peripheral wall of the cylinder structure composed ofthe bionic tissue engineering scaffold and the ribs is a whole, or an opening is formed in the peripheral wall. The bionic tissue engineering scaffold and the ribs are formed through 3D printing witha shape memory polymer as the printing material, and the shape memory polymer is one or more of shape memory polycaprolactone, shape memory polylactic acid and shape memory polyurethane. The glass simulating sponge support is used for designing and manufacturing a medical stent.

Description

technical field [0001] The invention relates to the field of medical stents, in particular to a medical stent and a preparation method thereof. Background technique [0002] With the development of society, health has become an issue of increasing concern to people. Faced with the threat of luminal diseases, medical stents have become an indispensable device and played a vital role. During the treatment of luminal diseases, medical stents made of stainless steel or nickel-titanium alloy without or with a recovery device are generally implanted into the lesion in the lumen through the original in vivo channel, so as to effectively treat the stenosis. Relieve the obstruction, block the fistula, and improve the quality of life of the patient. [0003] In order to ensure the support of the lesion area and the stability of the stent, the current stents are all alloy stents. The alloy stent has poor biocompatibility, complicated manufacturing process, and cannot change the size o...

Claims

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Application Information

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IPC IPC(8): A61F2/88B33Y10/00B33Y80/00A61L27/06A61L27/18A61L27/50A61L27/54
CPCA61F2/885A61F2210/0014A61F2250/0067A61L27/06A61L27/18A61L27/50A61L27/54A61L2300/412A61L2400/16B33Y10/00B33Y80/00C08L67/04C08L75/04
Inventor 刘彦菊冷劲松辛晓洲赵伟刘立武张风华
Owner HARBIN INST OF TECH
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