Curcumin liquid crystal with improved medicine bioavailability
一种姜黄素、液晶的技术,应用在姜黄素制备领域,能够解决生物利用度低、口服吸收少、稳定性差等问题,达到增强疗效、增强免疫力、提高稳定性和溶解性的效果
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example 1
[0017] Take 2 pieces of ginger and put them into a jet grinder to grind them into minced ginger, put 20g of minced ginger into a 500mL beaker, add 200mL of sodium hydroxide solution with a concentration of 0.02mol / L, transfer it to a water bath, raise the temperature to 50°C, and let it stand for extraction for 3 hours , filtered to obtain the alkaline water extract; take 100mL and add 15mL of acetone to the above alkaline water extract, stir for 1h with a magnetic stirrer at a stirring speed of 300r / min, separate the organic layer after standing for 1h, and move it into a distillation device , heated up to 80°C to distill off acetone, adjusted its pH value to 1 with a hydrochloric acid solution with a concentration of 0.02mol / L, allowed to stand for 2 hours to precipitate curcumin, dried at 60°C to constant weight to obtain curcumin powder; weighed Put 2g of triglycerides into a 200mL vial, add 6g of curcumin powder and 2g of acarbose prepared above, add 20mL of absolute ethan...
example 2
[0020] Take 3 pieces of ginger and put them into a jet grinder to grind them into minced ginger, put 25g of minced ginger into a 500mL beaker, add 250mL of sodium hydroxide solution with a concentration of 0.02mol / L, transfer it to a water bath, raise the temperature to 55°C, and let it stand for extraction for 4h , filtered to obtain the alkaline water extract; take 150mL and add 18mL acetone to the above alkaline water extract, stir for 1h with a magnetic stirrer at a stirring speed of 350r / min, separate and obtain the organic layer after standing for 1h, and move it into a distillation device , heated up to 85°C to distill off acetone, adjusted its pH value to 1 with a hydrochloric acid solution with a concentration of 0.02mol / L, allowed to stand for 2 hours to precipitate curcumin, dried at 65°C to constant weight to obtain curcumin powder; weighed Put 2g of triglycerides into a 200mL vial, then add 8g of curcumin powder and 3g of acarbose prepared above, add 25mL of absolu...
example 3
[0023] Take 3 pieces of ginger and put them into a jet grinder to grind them into minced ginger, put 30g of minced ginger into a 500mL beaker, add 300mL of sodium hydroxide solution with a concentration of 0.02mol / L, transfer it to a water bath, raise the temperature to 60°C, and let it stand for extraction for 6h , filtered to obtain the alkaline water extract; take 200mL and add 30mL acetone to the above alkaline water extract, stir for 2h with a magnetic stirrer at a stirring speed of 400r / min, separate the organic layer after standing for 2h, and move it into a distillation device , heated up to 90°C to distill off acetone, adjusted its pH value to 2 with a hydrochloric acid solution with a concentration of 0.02mol / L, allowed to stand for 3 hours to precipitate curcumin, dried at 70°C to constant weight to obtain curcumin powder; Put 3g of triglycerides into a 200mL vial, then add 10g of curcumin powder and 5g of acarbose prepared above, add 30mL of absolute ethanol dropwis...
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