Method for extracting syringic acid and recovering ionic liquid by using ionic liquid aqueous two-phase system

A two-phase system, ionic liquid technology, applied in the separation/purification of carboxylic acid compounds, organic chemistry and other directions, can solve the problems of complex extraction and recovery system construction, less application of two-phase system, toxic recovery of ionic liquids, etc. Achieve the effect of easy operation, short phase separation time, and easy amplification

Inactive Publication Date: 2018-12-04
JIANGSU UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, ionic liquids are generally more expensive, and they still have certain pollution and poisonous effects on food, and it is difficult to recover ionic liquids, so they are not widely used at present.
[0004] The ionic liquid two-phase aqueous system is a hot topic in recent years. It is widely used in the extraction of biological substances due to its advantages such as good biocompatibility. However, the application of the two-phase aqueous system on phenolic acids is rarely due to The construction of the extraction and recovery system is complex; it is of great significance to apply the ionic liquid two-phase aqueous system to the extraction of phenolic acids, and at the same time improve the recovery system of ionic liquids on this basis. Recycling Opens New Paths

Method used

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  • Method for extracting syringic acid and recovering ionic liquid by using ionic liquid aqueous two-phase system
  • Method for extracting syringic acid and recovering ionic liquid by using ionic liquid aqueous two-phase system
  • Method for extracting syringic acid and recovering ionic liquid by using ionic liquid aqueous two-phase system

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Experimental program
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Effect test

Embodiment 1

[0028] (1) Take 1.0g of 1-butyl-3-methylimidazolium trifluoromethanesulfonate in a centrifuge tube, then weigh 0.8gNa 2 CO 3 Add to the centrifuge tube, followed by adding 1g concentration of 3×10 -3 mol / L syringic acid solution, and finally add 7.2g of distilled water to supplement the total mass of the two-phase system to 10g to obtain an ionic liquid / sodium carbonate two-phase system. In order to test the accuracy of the data, each sample was equipped with three groups for parallel experiments.

[0029] (2) Shake the ionic liquid / sodium carbonate two-phase system obtained in step (1) with a vortex shaker for 5 minutes, then put it in a constant temperature water bath at 25°C and let it stand for 24 hours. The system is divided into an ionic liquid enriched phase and an inorganic salt enriched phase; syringic acid is extracted into the inorganic salt phase, and the extraction rate of syringic acid in the inorganic salt enriched phase is further calculated; the ionic liquid...

Embodiment 2

[0031] (1) Take 2.0g of 1-butyl-3-methylimidazolium trifluoromethanesulfonate in a centrifuge tube, then weigh 1g of Na 2 CO 3 Add to the centrifuge tube, followed by adding 1g concentration of 3×10 -3 mol / L syringic acid solution, and finally add 6g of distilled water to supplement the total mass of the two-phase system to 10g to obtain an ionic liquid / sodium carbonate two-phase system. In order to test the accuracy of the data, each sample was equipped with three groups for parallel experiments.

[0032] (2) Shake the configured ionic liquid / sodium carbonate two-phase system with a vortex shaker for 5 minutes, put it in a constant temperature water bath at 25°C and let it stand for 24 hours. The system is divided into an ionic liquid enriched phase and an inorganic salt enriched phase The syringic acid is extracted to the inorganic salt phase, and the extraction rate of the syringic acid in the inorganic salt-rich phase is further calculated; the ionic liquid phase can be ...

Embodiment 3

[0034] (1) Take 2.2g of 1-butyl-3-methylimidazolium trifluoromethanesulfonate in a centrifuge tube, then weigh 1.6g of Na 2 CO 3 Add to the centrifuge tube, followed by adding 1g concentration of 3×10 -3 mol / L syringic acid solution, and finally add 5.2g of distilled water to replenish the total mass of the two-phase system to 10g, to obtain an ionic liquid / sodium carbonate two-phase system. In order to test the accuracy of the data, each sample was equipped with three groups for parallel experiments.

[0035] (2) Shake the completed ionic liquid / sodium carbonate two-phase system with a vortex shaker for 5 minutes, put it in a constant temperature water bath at 25°C and let it stand for 24 hours. The system is divided into an ionic liquid-rich phase and an inorganic salt-rich phase. Syringic acid is extracted into the inorganic salt phase, and the extraction rate of syringic acid in the inorganic salt enriched phase is further calculated, and the ionic liquid enriched phase ...

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Abstract

The invention belongs to the technical field of biochemical separation, and more specifically relates to a method for extracting syringic acid and recovering ionic liquid by using an ionic liquid two-aqueous phase system. The method comprises the following step: a syringic acid solution is prepared, the ionic liquid, sodium carbonate, water, and the syringic acid solution are added to obtain a mixed solution, the mixed solution is shaken, and placed in a constant-temperature water bath for a standing reaction to complete the system phase separation, the ionic liquid-rich phase and the sodium carbonate-rich phase solution are respectively weighed and the syringic acid concentration is measured, the extraction rate is calculated, the ionic liquid-rich phase is directly taken out, and the ionic liquid is recovered by vacuum drying. The method has higher extraction efficiency, shorter phase-separation time, simple experimental condition, easy operation of a whole process, and easy enlargement, and is in favor of industrialization.

Description

technical field [0001] The invention belongs to the technical field of biochemical separation, and in particular relates to extracting syringic acid and recovering the ionic liquid by using an ionic liquid two-phase aqueous system. Background technique [0002] Phenolic acids are a class of organic acids containing phenolic rings that are found in many plants, especially in higher concentrations in dried fruits. In terms of health care, phenolic acids can refresh the mind, reduce fatigue, and beautify the skin; in medicine, phenolic acids can be used to lower cholesterol in the human body, treat high blood pressure and prevent cardiovascular diseases. These effects are mainly related to the structure of phenols with anti-oxidation and free radical scavenging. Natural phenolics are more effective than synthetic alternatives in nutraceutical and cosmetic applications. Syringic acid is one of the representatives of phenolic acids, mainly extracted from rhododendron and other ...

Claims

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Application Information

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IPC IPC(8): C07C51/48C07C65/21
CPCC07C51/48C07C65/21
Inventor 周存山杨宏朋余筱洁张磊李墨
Owner JIANGSU UNIV
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