Florfenicol soluble powder and preparation method thereof

A florfenicol and soluble technology, applied in the field of florfenicol soluble powder and its preparation, can solve the problem that the antibacterial effect of the drug does not significantly help and improve, affects product dispersion, dissolution speed and release speed, and clinical use. Inconvenience and other problems, to achieve the effect of prolonging the action time of the drug, avoiding the low bulk density of conventional production, and prolonging the action time
CN108969486AInactive Publication Date: 2018-12-11王琴
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
王琴
Publication Date
2018-12-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a florfenicol soluble powder and a preparation method thereof. The florfenicol soluble powder comprises the following components in parts by weight: 21.5-26.5 parts of florfenicol, 70.9-75.5% of inclusion agent, 0.8-1.5% of trimethoprim, 0.8-1 part of dispersing agent and 0.5-0.8 part of latent solvent. According to the florfenicol soluble powder and the preparation methodthereof disclosed by the invention, a molecular inclusion technology is adopted for solving the insoluble problem of florfenicol in water and greatly promoting the bioavailability of the product; through the improvement of technological parameters, the bulk density of common centrifugal spray technical products can be increased and the bulk density of products can reach up to the level more suitable for fodder enterprises and cultivation terminals; the product liquidity is promoted, the usage amount of packing materials is saved and the obvious social and economic benefits are created.
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Description

technical field

[0001] The invention belongs to the field of veterinary drug preparations, in particular to a florfenicol soluble powder and a preparation method thereof. Background technique

[0002] Florfenicol, also known as florfenicol, is an excellent broad-spectrum antibiotic for animals. It has the characteristics of broad antibacterial spectrum, good absorption, wide distribution in the body, safety and high efficiency, especially eliminates chloramphenicol that destroys bone marrow and hematopoiesis. Functional shortcomings, no potential aplastic anemia, teratogenic, carcinogenic and mutagenic effects. In veterinary medicine, it is widely used in the treatment of livestock and poultry bacterial diseases caused by sensitive bacteria, and the effect is remarkable. There is no problem of chloramphenicol residue, and it is not easy to produce drug resistance. It is the best substitute for thiamphenicol. However, the raw material of florfenicol is almost insoluble in wa...

Claims

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