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Preparation method and application of medical sweet potato leaf extracts with blood fat reducing effect

A blood lipid-lowering drug and sweet potato leaf technology are applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, and drug combinations, etc. problems such as low extraction efficiency, to achieve the effect of promoting thorough precipitation, improving extraction efficiency, and shortening extraction time

Inactive Publication Date: 2018-12-18
XUZHOU INST OF AGRI SCI IN JIANGSU XUHUAI DISTRICT (JIANGSU XUZHOU SWEETPOTATO CENT)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at the disadvantages of low extraction efficiency, incomplete precipitation and unclear function of sweet potato leaf alcohol-soluble components in the prior art. The present invention provides a preparation method and application of a medicinal sweet potato leaf extract with hypolipidemic effect. The technical scheme adopted is as follows:

Method used

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  • Preparation method and application of medical sweet potato leaf extracts with blood fat reducing effect
  • Preparation method and application of medical sweet potato leaf extracts with blood fat reducing effect
  • Preparation method and application of medical sweet potato leaf extracts with blood fat reducing effect

Examples

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Effect test

Embodiment 1

[0031] This embodiment provides a preparation method of medicinal sweet potato leaf extract with hypolipidemic effect, which is carried out according to the following steps:

[0032] Step 1: using fresh medicinal sweet potato Simeng No. 1 leaves as raw materials, after washing and removing impurities, freeze-drying in a freeze dryer, crushing, and passing through a 60-mesh sieve to obtain medicinal sweet potato leaf powder;

[0033] Step 2: Take the medicinal sweet potato leaf powder obtained in step 1, add 20% (v / v) ethanol solution to the medicinal sweet potato leaf powder according to the solid-liquid ratio of 1:8 (g / mL), and extract at an extraction temperature of 60 Under the condition of ℃ and ultrasonic power of 200W, start Jueng’s ultrasonic cycle extraction for 30min, filter to obtain filtrate I and residue;

[0034] Step 3: Take the residue obtained by filtering in Step 2, add 50% (v / v) ethanol solution according to the ratio of material to liquid of 1:8 (g / mL), and ...

Embodiment 2

[0040] The difference between this embodiment and Example 1 is that the quality of the medicinal sweet potato leaf extract (the supernatant finally obtained in step 6 in the above-mentioned medicinal sweet potato leaf extract method) is 100%, and the content of aspartame The addition amount is 0.3% (mass), and the addition amount of citric acid is 0.15% (mass). The oral liquid is brown in appearance without precipitation, the soluble solid content is 6.8°Brix, and the pH is 4.3.

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Abstract

The invention discloses a preparation method and application of medical sweet potato leaf extracts with a blood fat reducing effect, and belongs to the technical field of health care food. The methodcomprises the following steps that fresh medical sweet potato leaves are subjected to cleaning and impurity removal treatment and are then put into a freeze drying machine to be subjected to freeze drying; sieving is performed after the crushing; medical sweet potato leaveleaf powders are is obtained; after the gradient ethanol extraction and gradient extraction ultrasound extraction are performed, vacuum concentration is performed until the weight of the concentration liquid is 1.8 times of the weight of the medical sweet potato leaf powder; centrifugation is performed; liquid supernatant istaken; the medical sweet potato leaf extracts are obtained. The medical sweet potato leaf oral liquid has the effect of reducing the blood fat, and can be used for treating hyperlipidemia.

Description

technical field [0001] The invention relates to a preparation method and application of a medicinal sweet potato leaf extract with hypolipidemic effect, and belongs to the technical field of health food. Background technique [0002] Sweet potato leaves are rich in protein, cellulose, vitamins, calcium, phosphorus, iron, selenium and other minerals, as well as active ingredients such as flavonoids and carotenoids. The content of vitamin A is 4 times that of green amaranth, and vitamin B1 is 3.5 times that of spinach. The content of carotene is 3 times that of carrots. It is known as the "Queen of Vegetables" and "Longevity Food". cancer vegetables. [0003] Medicinal sweet potatoes, such as Simon No. 1, have much higher leaf nutritional components and bioactive substances than ordinary sweet potatoes. They not only contain all 8 essential amino acids needed by the human body, but also contain 112 μg of selenium, which is 200 times that of ordinary sweet potatoes. At presen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P3/06
CPCA61K9/0095A61K36/8945A61K47/183A61K2236/15A61K2236/17A61K2236/333A61K2236/39A61K2236/53A61P3/06
Inventor 钮福祥孙健张毅朱红徐飞岳瑞雪王洪云张文婷
Owner XUZHOU INST OF AGRI SCI IN JIANGSU XUHUAI DISTRICT (JIANGSU XUZHOU SWEETPOTATO CENT)
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